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The racemate of 12 was used in crystallization. As it is difficult to unambiguously discriminate between phosphorous and sulfur in X-ray crystallography, it remains uncertain whether the bound form was the less active R or indeed the more active S enantiomer of 12.
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The racemate of 12 was used in crystallization. As it is difficult to unambiguously discriminate between phosphorous and sulfur in X-ray crystallography, it remains uncertain whether the bound form was the less active R or indeed the more active S enantiomer of 12.
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