The study of the mechanism of the effect of heparin on tissue perfusion of sepsis patients

Chinese Critical Care Medicine

Volumn 20, Issue 9, 2008, Pages 550-552

  Yang, Chun Hua ^a   Guan, Xiang Dong ^a   Chen, Juan ^a   Ouyang, Bin ^a   Chen, Min Ying ^a   Li, Li Fen ^a   Huang, Shun Wei ^a   Kou, Qiu Ye ^a   Wu, Jian Feng ^a   Liu, Zi Meng ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

D dimer; Heparin; Lactic acid; Platelet count; Sepsis; Tissue perfusion

Indexed keywords

D DIMER; HEPARIN; LACTIC ACID;

ADOLESCENT; ADULT; AGED; ARTICLE; BLEEDING; BLEEDING TENDENCY; CLINICAL TRIAL; CONTINUOUS INFUSION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; DRUG RESPONSE; FEMALE; HUMAN; LACTATE BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; MICROVASCULATURE; PROTEIN BLOOD LEVEL; RANDOMIZED CONTROLLED TRIAL; SEPSIS; THROMBOCYTE COUNT; THROMBOCYTOPENIA; THROMBOSIS; TISSUE PERFUSION;

ADOLESCENT; ADULT; AGED; ANTICOAGULANTS; FEMALE; FIBRIN FIBRINOGEN DEGRADATION PRODUCTS; HEPARIN; HUMANS; LACTIC ACID; MALE; MIDDLE AGED; PLATELET COUNT; PROSPECTIVE STUDIES; SEPSIS; YOUNG ADULT;

EID: 54449086471     PISSN: 10030603     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (8)

1. Levy MM, Fink MP, Marshall JC, et al. 2001 SCCM/ESICMA/ACCP/ATS/SIS international sepsis definitions conference[J]. Crit Care Med, 2003, 31(4): 1250-1256.
2. Faust SN, Levin M, Harrison OB, et al. Dysfunction of endothelial protein C activation in severe meningococcal sepsis[J]. N Engl J Med, 2001, 345(6): 408-416.
3. Taylor FB Jr, Wada H, Kinasewitz G. Description of compensated and uncompensated disseminated intravascular coagulation (DIC) responses (non-overt and overt DIC) in baboon models of intravenous and intraperitoneal Escherichia coli sepsis and in the human model of endotoxemia: toward a better definition of DIC [J]. Crit Care Med, 2000, 28 (9 Suppl): S12-19.
4. Baughman RP, Lower EE, Flessa HC, et al. Thrombocytopenia in the intensive care unit[J]. Chest, 1993, 104(4): 1243-1247.
5. Stéphan F, Hollande J, Richard O, et al. Thrombocytopenia in a surgical ICU[J]. Chest, 1999, 115(5): 1363-1370.
6. Francois B, Trimoreau F, Vignon P, et al. Thrombocytopenia in the sepsis syndrome: role of hemophagocytosis and macrophage colony-stimulating factor [J]. Am J Med, 1997, 103(3): 114-420.
7. Chinese source.
8. Sakr Y, Dubois MJ, De backer D, et al. Persistent microcirculatory alterations are associated with organ failure and death in patients with septic shock[J]. Crit Care Med, 2004, 32(9): 1963-1964.