Separation, determination and identification of the diastereoisomers of podophyllotoxin and its esters by high-performance liquid chromatography/tandem mass spectrometry

Journal of Chromatography A

Volumn 1210, Issue 2, 2008, Pages 168-177

  Zhao, Lei ^a,b   Tian, Xuan ^a   Fan, Peng Cheng ^c   Zhan, Yun Jing ^b   Shen, Da Wei ^a   Jin, Yan ^a  

^a LANZHOU UNIVERSITY   (China)

^b GANSU UNIVERSITY OF CHINESE MEDICINE   (China)

^c LANZHOU GENERAL HOSPITAL   (China)

Author keywords

Diastereoisomers separation; HPLC ESI MS MS; Podophyllotoxin; Relative abundance

Indexed keywords

BIOCHEMISTRY; BODY FLUIDS; CHEMICAL REACTIONS; CHROMATOGRAPHIC ANALYSIS; CHROMATOGRAPHY; COLUMNS (STRUCTURAL); ELECTROLYSIS; ELECTROSPRAY IONIZATION; ESTERIFICATION; ESTERS; GRAFTING (CHEMICAL); HIGH PRESSURE LIQUID CHROMATOGRAPHY; IONIZATION OF LIQUIDS; IONS; ISOMERS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETERS; MASS SPECTROMETRY; ORGANIC COMPOUNDS; SEPARATION; SPECTROMETERS; SPECTROMETRY; SPECTRUM ANALYSIS; SYNTHESIS (CHEMICAL);

CHROMATOGRAPHIC CONDITIONS; DIASTEREOISOMERS; DIASTEREOISOMERS SEPARATION; DIODE ARRAY DETECTIONS; EPIMERIZATION; HIGH-PERFORMANCE; HIGH-PERFORMANCE LIQUID CHROMATOGRAPHIES; HPLC-ESI/MS/MS; HYPERSIL; LIGNANS; LIQUID CHROMATOGRAPHY/TANDEM MASS SPECTROMETRIES; NATURAL PRODUCTS; OPTIMUM CONDITIONS; PODOPHYLLOTOXIN; PROTONATED; RELATIVE ABUNDANCE; RELATIVE ABUNDANCES; SAMPLE SOLUTIONS; SEPARATION AND IDENTIFICATIONS; STEREOCHEMICAL EFFECTS; TANDEM MASS SPECTROMETRIES;

HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

ESTER; LIGNAN; PODOPHYLLOTOXIN; PROTON;

ARTICLE; ASSAY; CHEMICAL REACTION; DIASTEREOISOMER; ELECTROSPRAY MASS SPECTROMETRY; EPIMER; EPIMERIZATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METABOLISM; PRIORITY JOURNAL; SEPARATION TECHNIQUE; TANDEM MASS SPECTROMETRY;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ESTERS; PODOPHYLLOTOXIN; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; STEREOISOMERISM; TANDEM MASS SPECTROMETRY;

EID: 54449083746     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2008.09.057     Document Type: Article

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