-
1
-
-
33747368274
-
Expression of mammalian GPCRs in C. elegans generates novel behavioural responses to human ligands
-
Teng MS, et al. (2006) Expression of mammalian GPCRs in C. elegans generates novel behavioural responses to human ligands. BMC Biol 4:22.
-
(2006)
BMC Biol
, vol.4
, pp. 22
-
-
Teng, M.S.1
-
2
-
-
31544457058
-
Dietary choice behavior in Caenorhabditis elegans
-
Shtonda BB, Avery L (2006) Dietary choice behavior in Caenorhabditis elegans. J Exp Biol 209:89-102.
-
(2006)
J Exp Biol
, vol.209
, pp. 89-102
-
-
Shtonda, B.B.1
Avery, L.2
-
3
-
-
0028806172
-
BB-10010: An active variant of human macrophage inflammatory protein-1 alpha with improved pharmaceutical properties
-
Hunter MG, et al. (1995) BB-10010: An active variant of human macrophage inflammatory protein-1 alpha with improved pharmaceutical properties. Blood 86:4400-4408.
-
(1995)
Blood
, vol.86
, pp. 4400-4408
-
-
Hunter, M.G.1
-
4
-
-
0033522887
-
Identification of amino acid residues critical for aggregation of human CC chemokines macrophage inflammatory protein (MIP)-1alpha, MIP-1beta, and RANTES Characterization of active disaggregated chemokine variants
-
Czaplewski LG, et al. (1999) Identification of amino acid residues critical for aggregation of human CC chemokines macrophage inflammatory protein (MIP)-1alpha, MIP-1beta, and RANTES Characterization of active disaggregated chemokine variants. J Biol Chem 274:16077-16084.
-
(1999)
J Biol Chem
, vol.274
, pp. 16077-16084
-
-
Czaplewski, L.G.1
-
5
-
-
33747172021
-
Diverse signalling by different chemokines through the chemokine receptor CCR5
-
Mueller A, Mahmoud NG, Strange PG (2006) Diverse signalling by different chemokines through the chemokine receptor CCR5. Biochem Pharmacol 72:739-748.
-
(2006)
Biochem Pharmacol
, vol.72
, pp. 739-748
-
-
Mueller, A.1
Mahmoud, N.G.2
Strange, P.G.3
-
6
-
-
0029010408
-
Structure-activity relationships of chemokines
-
Clark-Lewis I, et al. (1995) Structure-activity relationships of chemokines. J Leukocyte Biol 57:703-711.
-
(1995)
J Leukocyte Biol
, vol.57
, pp. 703-711
-
-
Clark-Lewis, I.1
-
7
-
-
0024403619
-
High-resolution epitope mapping of hGH-receptor interactions by alanine-scanning mutagenesis
-
Cunningham BC, Wells JA (1989) High-resolution epitope mapping of hGH-receptor interactions by alanine-scanning mutagenesis. Science 244:1081-1085.
-
(1989)
Science
, vol.244
, pp. 1081-1085
-
-
Cunningham, B.C.1
Wells, J.A.2
-
8
-
-
0026350498
-
Systematic mutational analyses of protein-protein interfaces
-
Wells JA (1991) Systematic mutational analyses of protein-protein interfaces. Methods Enzymol 202:390-411.
-
(1991)
Methods Enzymol
, vol.202
, pp. 390-411
-
-
Wells, J.A.1
-
9
-
-
0031260472
-
A bioluminescent assay for agonist activity at potentially any G-protein-coupled receptor
-
Stables J, et al. (1997) A bioluminescent assay for agonist activity at potentially any G-protein-coupled receptor. Anal Biochem 252:115-126.
-
(1997)
Anal Biochem
, vol.252
, pp. 115-126
-
-
Stables, J.1
-
10
-
-
0034694019
-
Natural proteolytic processing of hemofiltrate CC chemokine 1 generates a potent CC chemokine receptor (CCR)1 and CCR5 agonist with anti-HIV properties
-
Detheux M, et al. (2000) Natural proteolytic processing of hemofiltrate CC chemokine 1 generates a potent CC chemokine receptor (CCR)1 and CCR5 agonist with anti-HIV properties. J Exp Med 192:1501-1508.
-
(2000)
J Exp Med
, vol.192
, pp. 1501-1508
-
-
Detheux, M.1
-
11
-
-
0037137183
-
Characterization of the role of the N-loop of MIP-1 beta in CCR5 binding
-
Bondue A, et al. (2002) Characterization of the role of the N-loop of MIP-1 beta in CCR5 binding. Biochemistry 41:13548-13555.
-
(2002)
Biochemistry
, vol.41
, pp. 13548-13555
-
-
Bondue, A.1
-
12
-
-
0034724373
-
CC chemokine MIP-1 beta can function as a monomer and depends on Phe13 for receptor binding
-
Laurence JS, et al. (2000) CC chemokine MIP-1 beta can function as a monomer and depends on Phe13 for receptor binding. Biochemistry 39:3401-3409.
-
(2000)
Biochemistry
, vol.39
, pp. 3401-3409
-
-
Laurence, J.S.1
-
13
-
-
15844391876
-
RANTES and MCP-3 antagonists bind multiple chemokine receptors
-
Gong JH, et al. (1996) RANTES and MCP-3 antagonists bind multiple chemokine receptors. J Biol Chem 271:10521-10527.
-
(1996)
J Biol Chem
, vol.271
, pp. 10521-10527
-
-
Gong, J.H.1
-
14
-
-
0028952523
-
Antagonists of monocyte chemoattractant protein 1 identified by modification of functionally critical NH2-terminal residues
-
Gong JH, Clark-Lewis I (1995) Antagonists of monocyte chemoattractant protein 1 identified by modification of functionally critical NH2-terminal residues. J Exp Med 181:631-640.
-
(1995)
J Exp Med
, vol.181
, pp. 631-640
-
-
Gong, J.H.1
Clark-Lewis, I.2
-
15
-
-
0030811908
-
Distinct but overlapping epitopes for the interaction of a CC-chemokine with CCR1, CCR3 and CCR5
-
Pakianathan DR, et al. (1997) Distinct but overlapping epitopes for the interaction of a CC-chemokine with CCR1, CCR3 and CCR5. Biochemistry 36:9642-9648.
-
(1997)
Biochemistry
, vol.36
, pp. 9642-9648
-
-
Pakianathan, D.R.1
-
16
-
-
0029670775
-
Deletion of the NH2-terminal residue converts monocyte chemotactic protein 1 from an activator of basophil mediator release to an eosinophil chemoattractant
-
Weber M, et al. (1996) Deletion of the NH2-terminal residue converts monocyte chemotactic protein 1 from an activator of basophil mediator release to an eosinophil chemoattractant. J Exp Med 183:681-685.
-
(1996)
J Exp Med
, vol.183
, pp. 681-685
-
-
Weber, M.1
-
17
-
-
0344528793
-
Dynamics study on the anti-human immunodeficiency virus chemokine viral macrophage-inflammatory protein-II (VMIP-II) reveals a fully monomeric protein
-
LiWang AC, et al. (1999) Dynamics study on the anti-human immunodeficiency virus chemokine viral macrophage-inflammatory protein-II (VMIP-II) reveals a fully monomeric protein. Biochemistry 38:442-453.
-
(1999)
Biochemistry
, vol.38
, pp. 442-453
-
-
LiWang, A.C.1
-
18
-
-
0035845586
-
Structural comparison of monomeric variants of the chemokine MIP-1beta having differing ability to bind the receptor CCR5
-
Kim S, Jao S, Laurence JS, LiWang PJ (2001) Structural comparison of monomeric variants of the chemokine MIP-1beta having differing ability to bind the receptor CCR5. Biochemistry 40:10782-10791.
-
(2001)
Biochemistry
, vol.40
, pp. 10782-10791
-
-
Kim, S.1
Jao, S.2
Laurence, J.S.3
LiWang, P.J.4
-
19
-
-
0033515588
-
Epitope mapping of CCR5 reveals multiple conformational states and distinct but overlapping structures involved in chemokine and coreceptor function
-
Lee B, et al. (1999) Epitope mapping of CCR5 reveals multiple conformational states and distinct but overlapping structures involved in chemokine and coreceptor function. J Biol Chem 274:9617-9626.
-
(1999)
J Biol Chem
, vol.274
, pp. 9617-9626
-
-
Lee, B.1
-
20
-
-
0030763382
-
The second extracellular loop of CCR5 is the major determinant of ligand specificity
-
Samson M, et al. (1997) The second extracellular loop of CCR5 is the major determinant of ligand specificity. J Biol Chem 272:24934-24941.
-
(1997)
J Biol Chem
, vol.272
, pp. 24934-24941
-
-
Samson, M.1
-
21
-
-
0030779808
-
Interaction of chemokine receptor CCR5 with its ligands: Multiple domains for HIV-1 gp120 binding and a single domain for chemokine binding
-
Wu L, et al. (1997) Interaction of chemokine receptor CCR5 with its ligands: Multiple domains for HIV-1 gp120 binding and a single domain for chemokine binding. J Exp Med 186:1373-1381.
-
(1997)
J Exp Med
, vol.186
, pp. 1373-1381
-
-
Wu, L.1
-
22
-
-
0031984539
-
Amino-terminal substitutions in the CCR5 coreceptor impair gp120 binding and human immunodeficiency virus type 1 entry
-
Dragic T, et al. (1998) Amino-terminal substitutions in the CCR5 coreceptor impair gp120 binding and human immunodeficiency virus type 1 entry. J Virol 72:279-285.
-
(1998)
J Virol
, vol.72
, pp. 279-285
-
-
Dragic, T.1
-
23
-
-
0033520930
-
Multiple charged and aromatic residues in CCR5 amino-terminal domain are involved in high affinity binding of both chemokines and HIV-1 Env protein
-
Blanpain C, et al. (1999) Multiple charged and aromatic residues in CCR5 amino-terminal domain are involved in high affinity binding of both chemokines and HIV-1 Env protein. J Biol Chem 274:34719-34727.
-
(1999)
J Biol Chem
, vol.274
, pp. 34719-34727
-
-
Blanpain, C.1
-
24
-
-
0035942317
-
Importance of basic residues and quaternary structure in the function of MIP-1 beta: CCR5 binding and cell surface sugar interactions
-
Laurence JS, et al. (2001) Importance of basic residues and quaternary structure in the function of MIP-1 beta: CCR5 binding and cell surface sugar interactions. Biochemistry 40:4990-4999.
-
(2001)
Biochemistry
, vol.40
, pp. 4990-4999
-
-
Laurence, J.S.1
-
25
-
-
0033566956
-
Structure and function of the glycosaminoglycan binding site of chemokine macrophage-inflammatory protein-1 beta
-
Koopmann W, Ediriwickrema C, Krangel MS (1999) Structure and function of the glycosaminoglycan binding site of chemokine macrophage-inflammatory protein-1 beta. J Immunol 163:2120-2127.
-
(1999)
J Immunol
, vol.163
, pp. 2120-2127
-
-
Koopmann, W.1
Ediriwickrema, C.2
Krangel, M.S.3
-
26
-
-
33646933785
-
A small-molecule screen in C. elegans yields a new calcium channel antagonist
-
Kwok TC, et al. (2006) A small-molecule screen in C. elegans yields a new calcium channel antagonist. Nature 441:91-95.
-
(2006)
Nature
, vol.441
, pp. 91-95
-
-
Kwok, T.C.1
-
28
-
-
34248598584
-
Invertebrate animal models of diseases as screening tools in drug discovery
-
Segalat L (2007) Invertebrate animal models of diseases as screening tools in drug discovery. ACS Chem Biol 2:231-236.
-
(2007)
ACS Chem Biol
, vol.2
, pp. 231-236
-
-
Segalat, L.1
-
29
-
-
35348861272
-
Drug discovery: Here comes the worm
-
Segalat L (2006) Drug discovery: Here comes the worm. ACS Chem Biol 1:277-278.
-
(2006)
ACS Chem Biol
, vol.1
, pp. 277-278
-
-
Segalat, L.1
-
30
-
-
0037470996
-
Identification of a testicular odorant receptor mediating human sperm chemotaxis
-
Spehr M, et al. (2003) Identification of a testicular odorant receptor mediating human sperm chemotaxis. Science 299:2054-2058.
-
(2003)
Science
, vol.299
, pp. 2054-2058
-
-
Spehr, M.1
-
31
-
-
0037147674
-
Functional expression of a mammalian olfactory receptor in Caenorhabditis elegans
-
Milani N, et al. (2002) Functional expression of a mammalian olfactory receptor in Caenorhabditis elegans. NeuroReport 13:2515-2520.
-
(2002)
NeuroReport
, vol.13
, pp. 2515-2520
-
-
Milani, N.1
-
32
-
-
34247640671
-
Evolving the lock to fit the key to create a family of G protein-coupled receptors potently activated by an inert ligand
-
Armbruster BN, et al. (2007) Evolving the lock to fit the key to create a family of G protein-coupled receptors potently activated by an inert ligand. Proc Natl Acad Sci USA 104:5163-5168.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 5163-5168
-
-
Armbruster, B.N.1
-
33
-
-
33947399187
-
Rapid identification of functionally critical amino acids in a G protein-coupled receptor
-
Li B, et al. (2007) Rapid identification of functionally critical amino acids in a G protein-coupled receptor. Nat Methods 4:169-174.
-
(2007)
Nat Methods
, vol.4
, pp. 169-174
-
-
Li, B.1
-
34
-
-
0025942107
-
Efficient gene transfer in C.elegans: Extrachromosomal maintenance and integration of transforming sequences
-
Mello CC, Kramer JM, Stinchcomb D, Ambros V (1991) Efficient gene transfer in C.elegans: Extrachromosomal maintenance and integration of transforming sequences. EMBO J 10:3959-3970.
-
(1991)
EMBO J
, vol.10
, pp. 3959-3970
-
-
Mello, C.C.1
Kramer, J.M.2
Stinchcomb, D.3
Ambros, V.4
-
35
-
-
0016063911
-
The genetics of Caenorhabditis elegans
-
Brenner S (1974) The genetics of Caenorhabditis elegans. Genetics 77:71-94.
-
(1974)
Genetics
, vol.77
, pp. 71-94
-
-
Brenner, S.1
-
36
-
-
33845913565
-
A simple vector system to improve performance and utilisation of recombinant antibodies
-
Martin CD, et al. (2006) A simple vector system to improve performance and utilisation of recombinant antibodies. BMC Biotechnol 6:46.
-
(2006)
BMC Biotechnol
, vol.6
, pp. 46
-
-
Martin, C.D.1
-
37
-
-
0023613953
-
Rapid and efficient site-specific mutagenesis without phenotypic selection
-
Kunkel TA, Roberts JD, Zakour RA (1987) Rapid and efficient site-specific mutagenesis without phenotypic selection. Methods Enzymol 154:367-382.
-
(1987)
Methods Enzymol
, vol.154
, pp. 367-382
-
-
Kunkel, T.A.1
Roberts, J.D.2
Zakour, R.A.3
-
38
-
-
14844294424
-
Protein production by auto-induction in high density shaking cultures
-
Studier FW (2005) Protein production by auto-induction in high density shaking cultures. Protein Expr Purif 41:207-234.
-
(2005)
Protein Expr Purif
, vol.41
, pp. 207-234
-
-
Studier, F.W.1
-
39
-
-
0033567969
-
CCR5 binds multiple CC-chemokines: MCP-3 acts as a natural antagonist
-
Blanpain C, et al. (1999) CCR5 binds multiple CC-chemokines: MCP-3 acts as a natural antagonist. Blood 94:1899-1905.
-
(1999)
Blood
, vol.94
, pp. 1899-1905
-
-
Blanpain, C.1
|