Trace determination of anthracyclines in urine: A new high-performance liquid chromatography/tandem mass spectrometry method for assessing exposure of hospital personnel

Rapid Communications in Mass Spectrometry

Volumn 18, Issue 20, 2004, Pages 2426-2436

  Sottani, Cristina ^a   Tranfo, Giovanna ^b   Bettinelli, Maurizio ^a   Faranda, Paolo ^b   Spagnoli, Mariangela ^b   Minoia, Claudio ^a  

^a IRCCS   (Italy)

^b ISPESL   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BODY FLUIDS; DICHLOROMETHANE; DRUG DOSAGE; DRUG PRODUCTS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; TRACE ANALYSIS;

ANALYTES; ANTHRACYCLINES; BIOLOGICAL MONITORING; DAUNORUBICIN; DOXORUBICIN; EPIRUBICIN; HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY; NEW HIGH; RELATIVE STANDARDS DEVIATIONS; TRACE DETERMINATION;

PHASE SEPARATION;

2 PROPANOL; ANTHRACYCLINE DERIVATIVE; ANTINEOPLASTIC AGENT; DAUNORUBICIN; DAUNORUBICIN DERIVATIVE; DICHLOROMETHANE; DOXORUBICIN; EPIDAUNORUBICIN; EPIRUBICIN; IDARUBICIN; UNCLASSIFIED DRUG;

ACCURACY; ANALYTIC METHOD; ARTICLE; BIOLOGICAL MONITORING; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG DETERMINATION; DRUG URINE LEVEL; EVALUATION; EVAPORATION; HEALTH CARE PERSONNEL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HOSPITAL PERSONNEL; HUMAN; LOW DRUG DOSE; OCCUPATIONAL EXPOSURE; PARAMETER; QUANTITATIVE ANALYSIS; SAMPLING; SENSITIVITY AND SPECIFICITY; SOLID PHASE EXTRACTION; STANDARD; TANDEM MASS SPECTROMETRY; TECHNIQUE; URINALYSIS; VALIDATION PROCESS;

EID: 5444254948     PISSN: 09514198     EISSN: None     Source Type: Journal    
DOI: 10.1002/rcm.1642     Document Type: Article

References (24)

1. Hortobágyi GN. Drugs 1977; 54(suppl 4): 1.
2. Weiss RB. Semin. Oncol. 1992; 19: 670.
3. Cassinelli G, Ballabio M, Arcamone F, Casazza AM, Podesta A. J. Antibiot. 1985; 38: 856.
4. Moro E, Bellotti V, Jannuzzo MG, Stegnjaich S, Valzelli G. J. Chromatogr. 1983; 274: 281.
5. Oosterbaan MJ, Dirks RJ, Vree TB, van der Kleijn E. J. Chromatogr. 1984; 306: 323.
6. Cummings J. J. Chromatogr. 1985; 341: 401.
7. Cummings J, Milroy R, Banham SW, Kaye SB. Cancer Chemother. Pharmacol. 1987; 19: 296.
8. Camaggi CM, Carisi P, Strocchi E, Pannuti F. Cancer Chemother. Pharmacol. 1992; 30: 303.
9. Eksborg S, Nilsson B. J. Chromatogr. 1989; 488: 427.
10. Kuhulmann O, Hofmann S, Weiss M. J. Chromatogr. B 1999; 728: 279.
11. Perez-Rulz T, Martinez-Lozano C, Sanz A, Bravo E. Elelectrophoresis 2001; 22: 134.
12. Fogli S, Danesi R, Innocenti F, Di Paolo A, Bocci G, Barbara C, Del Tacca M. Ther. Drag Monit. 1999; 21: 367.
13. de Bruijn P, Verweij J, Loos WJ, Kolker HJ, Planting AST, Nooter K, Storter G, Sparreboom A. Anal. Biochem. 1999; 266: 216.
14. Nicholls G, Clark BJ, Brown JE. J. Pharmaceut. Biomed. Anal. 1993; 10: 949.
15. van Aspern J, van Tellingen O, Beijnen JH. J. Chromatogr. B 1998; 712: 129.
16. Andersen A, Warren JD, Slørdal L. Ther. Drug Monit. 1993; 15: 455.
17. Camaggi CM, Carisi P, Strocchi E, Pannuti F. Cancer Chemother. Pharmacol. 1992; 30: 303.
18. Beijnen JH, Meenhorst PL, van Gijn R, Fromme M, Rosing H, Underberg WJM. J. Pharmaceut. Biomed. Anal. 1991; 9: 995.
19. Angerer J, Schaller K-H (eds). Analyses of Hazardous Substances in Biological Materials, vol. 7. Wiley-VCH: Weinheim, 2001; 119-141.
20. Barker KI, Crawford SM, Fell AF. J. Chromatogr. B 1996; 681: 323.
21. Dodde WIW, Maring JG, Hendriks G, Wachters FM, Groen HJM, de Vries GEE, Uges DRA. Ther. Drug Monit. 2003; 25: 433.
22. Lachâtre F, Parquet P, Ragot S, Gaulier JM, Cardot P, Dupuy JL. J. Chromatogr. B 2000; 738: 281.
23. TLVs and BEIs. Threshold limit values for chemical substances and physical agents and biological exposure indices. ACGIH: Cincinnati, Ohio, 2001.
24. EURACHEM/CITAC. EURACHEM/CITAC Guide-Quantifying uncertainty in analytical measurement (2nd edn). Final Draft, EURACHEM, 2000.