Nosocomial plasmids responsible for multiresistance of bacterial isolates at different wards of the Children's University Hospital in Bratislava, Slovakia

Journal of Applied Research

Volumn 4, Issue 2, 2004, Pages 312-320

  Vrabelova M ^a   Kollarova K ^a   Michalkova Papajova, D ^a   Hanzen, J ^b   Milosovic P ^b   Macickova T ^c   Kettner, M ^a  

^a Physics and Informatics   (Slovakia)

^b HPL spol s ro   (Slovakia)

^c INSTITUTE OF EXPERIMENTAL PHARMACOLOGY AND TOXICOLOGY   (Slovakia)

Author keywords

Antibiotic resistance; Enterobacteriaceae; Nosocomial plasmids

Indexed keywords

AMIKACIN; AMINOGLYCOSIDE; AMPICILLIN; AZTREONAM; BETA LACTAMASE; CEFEPIME; CEFOTAXIME; CEFOXITIN; CEFTAZIDIME; CEFTRIAXONE; CEPHALOSPORIN DERIVATIVE; CIPROFLOXACIN; GENTAMICIN; ISEPAMICIN; MEROPENEM; NETILMICIN; OFLOXACIN; PLASMID DNA; QUINOLINE DERIVED ANTIINFECTIVE AGENT; TOBRAMYCIN;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIUM ISOLATE; ENTEROBACTERIACEAE; HOSPITAL INFECTION; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MULTIDRUG RESISTANCE; NONHUMAN; PLASMID; SLOVAKIA; UNIVERSITY HOSPITAL; WARD;

EID: 5444252744     PISSN: 1537064X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Ford-Jones EL, Mindorff CM, Langley JM, et al. Epidemiologic study of 4684 hospital-acquired infections in pediatric patients. Pediatr Infect Dis J. 1989;8:668-675.
2. Appelgren P, Hellström I, Weitzberg E, Söderlund V, Bindslev V, Ransjö U. Risk factors for nosocomial intensive care infection: a long-term prospective analysis. Acta Anaesthesiol Scand. 2001;45:710-719.
3. Stover BH, Shulman ST, Bratcher DF, Brady MT, Levine GL, Jarvis WR. Nosocomial infections rates in US children's hospitals neonatal and pediatric intensive care units. Am J Infect Control. 2001;29:152-157.
4. st century: characterization, epidemiology and detection of this important resistance threat. Clin Microbiol Rev. 2001;14:933-951.
5. Jones RN. Resistance patterns among nosocomial pathogens. Chest. 2001;119:3978-4048.
6. National Committee for Clinical Laboratory Standards (NCCLS). Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically. Approved standard M7-A5; 2000. Wayne, Penn.
7. Kettner M, Navarová J, Rydl Z, Knothe H, Lebek G, Krěméry V. Occurrence of aminoglycoside-modifying enzymes in resistant strains of enterobacteria and Pseudomonas aeruginosa from several countries. J Antimicrob Chemother. 1981;8:175-185.
8. Shaw KJ, Rather PN, Hare RS, Miller GH. Molecular genetics of aminoglycoside resistance genes and familial relationships of the aminoglycoside-modifying enzymes. Microbiol Rev. 1993;57:138-163.
9. O'Callaghan CH, Morris A, Kirby SM, Shingler AH. Novel method for detection of beta-lactamase by using a chromogenic cephalosporin substrate. Antimicrob Agents Chemother. 1972;1:283-288.
10. Jarlier V, Nicolas M, Fournier G, Philippon A. Extended broad-spectrum beta-lactamases conferring transferable resistance to newer beta-lactam agents in Enterobacteriaceae: hospital prevalence and susceptibility patterns. Rev Infect Dis. 1988;10:867-878.
11. Stapleton P, Wu PJ, King A, Shannon K, French G, Phillips I. Incidence and mechanisms of resistance to the combination of amoxicillin and clavulanic acid in Escherichia coli. Antimicrob Agents Chemother. 1995;39:2478-2483.
12. Vrábelová M, Černická J, Kvač kajová J, et al. Occurrence of aminoglycoside-modifying enzymes and beta-lactamases in Acinetobacter spp., isolated from different hospitals in Bratislava. Biologia. 2003;58:1087-1094.
13. Kettner M, Milošovič P, Hletková M. Kallová J. Incidence and mechanism of aminoglycoside resistance in Pseudomonas aeruginosa serotype O11 isolates. Infection. 1995;23:380-383.
14. Takahashi S, Nagano Y. Rapid procedure for isolation of plasmid DNA and application to epidemiological analysis. J Clin Microbiol. 1984;20:608-613.
15. Qiagen. Qiagen Plasmid Purification Handbook. 2000;09:16-19.
16. Struelens MJ. The epidemiology of antimicrobial resistance in hospital-acquired infections: problems and possible solutions. British Med J. 1998;317:652-654.
17. Milošovič P, Mačičková T, Kettner M, Kallová J. Development of amikacin resistance in bacterial isolates in Slovakia (1990-1992). Int J Antimicrob Agents. 1994;4:69-71.
18. Bradford PA, Cherubin CE, Idemyor V, Rasmussen BA, Bush K. Multiply resistant K. pneumoniae strains from two Chicago Hospitals: identification of the extended-spectrum TEM-12 and TEM-10 ceftazidime-hydrolyzing beta-lactamases in a single isolate. Antimicrob Agents Chemother. 1994;38:761-766.
19. Peňa C, Pujol M, Ricart A, et al. Risk factors for fecal carriage of Klebsiella pneumoniae producing ESBL in the intensive care unit. J Hosp Infect. 1997;35:9-16.
20. Rice LB. Successful intervention for Gram-negative resistance to extended-spectrum beta-lactam antibiotics. Pharmacotherapy. 1999;19:1205-1285.
21. Rupp ME, Fey PD. Extended-spectrum beta-lactamase-producing Enterobacteriaceae consideration for diagnosis, prevention and drug treatment. Drugs. 2003;63:353-365.
22. Araque M, Nieves B, Ruiz O, Dagert M. Characterization of plasmids which mediate resistance to multiple antibiotics in Gram-negative bacteria of nosocomial origin. Enferm Infec Microbiol Clin. 1997;15:299-305.
23. Marchandin H, Carriere C, Sirot D, Jean-Pierre H, Darbas H. TEM-24 produced by four different species of Enterobacteriaceae, including Providencia rettgeri. in a single patient. Antimicrob Agents Chemother. 1999;43:2069-2073.
24. Jalaluddin S, Devaster J, Scheen R, Gerard M, Butller JP. Molecular epidemiological study of nosocomial Enterobacter aerogenex isolates in a Belgian Hospital. J Clin Microbiol. 1998;36:1846-1852.