Use of 99mTc-sestamibi gated SPECT to assess the influence of anterograde flow before primary coronary angioplasty on tissue salvage and functional recovery in acute myocardial infarction

European Journal of Nuclear Medicine and Molecular Imaging

Volumn 31, Issue 10, 2004, Pages 1378-1385

  Leoncini, Mario ^a   Bellandi, Francesco ^a   Sciagrà, Roberto ^b   Maioli, Mauro ^a   Toso, Anna ^a   Sestini, Stelvio ^a   Coppola, Angela ^a   Mennuti, Alberto ^a   Dabizzi, Roberto Piero ^a   Pupi, Alberto ^b  

^a MISERICORDIA E DOLCE HOSPITAL   (Italy)

^b UNIVERSITY OF FLORENCE   (Italy)

Author keywords

Abciximab; Angioplasty; Myocardial infarction; Scintigraphy

Indexed keywords

ABCIXIMAB; ACETYLSALICYLIC ACID; CLOPIDOGREL; HEPARIN; METHOXY ISOBUTYL ISONITRILE TECHNETIUM TC 99M; DIAGNOSTIC AGENT; RADIOPHARMACEUTICAL AGENT;

ACUTE HEART INFARCTION; ADULT; AGED; ARTICLE; BLOOD CLOT LYSIS; CLINICAL ARTICLE; CORONARY STENT; FEMALE; HEART LEFT VENTRICLE; HEART LEFT VENTRICLE EJECTION FRACTION; HEART MUSCLE PERFUSION; HEART MUSCLE REPERFUSION; HEART VENTRICLE ENDDIASTOLIC PRESSURE; HEART VENTRICLE VOLUME; HEART VENTRICLE WALL MOTION; HUMAN; MALE; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; TRANSLUMINAL CORONARY ANGIOPLASTY; BLOOD FLOW VELOCITY; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CONVALESCENCE; CORONARY ARTERY BLOOD FLOW; CORONARY BLOOD VESSEL; GATED IMAGING; HEART INFARCTION; HEART LEFT VENTRICLE FUNCTION; HEART VENTRICLE; METHODOLOGY; MIDDLE AGED; PATHOPHYSIOLOGY; PHYSIOLOGY; PREOPERATIVE CARE; PROGNOSIS; REPRODUCIBILITY; RISK ASSESSMENT; RISK FACTOR; SALVAGE THERAPY; SCINTISCANNING; SENSITIVITY AND SPECIFICITY; TREATMENT OUTCOME; VALIDATION STUDY;

ANGIOPLASTY, TRANSLUMINAL, PERCUTANEOUS CORONARY; BLOOD FLOW VELOCITY; CORONARY CIRCULATION; CORONARY VESSELS; FEMALE; GATED BLOOD-POOL IMAGING; HEART VENTRICLES; HUMANS; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; PREOPERATIVE CARE; PROGNOSIS; RADIOPHARMACEUTICALS; RECOVERY OF FUNCTION; REPRODUCIBILITY OF RESULTS; RISK ASSESSMENT; RISK FACTORS; SALVAGE THERAPY; SENSITIVITY AND SPECIFICITY; TECHNETIUM TC 99M SESTAMIBI; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON; TREATMENT OUTCOME; VENTRICULAR DYSFUNCTION, LEFT;

EID: 5444251570     PISSN: 16197070     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00259-004-1595-9     Document Type: Article

References (30)

1. 99mTc- hexakis-2-methoxy-2-methylpropyl-isonitrile imaging for the assessment of myocardial area at risk and the effect of treatment in acute myocardial infarction. Circulation 1989;80:1277-85
2. Santoro GM, Bisi G, Sciagrà R, Leoncini M, Fazzini PF, Meldolesi U Single photon emission tomography with technetium-99m hexakis 2-methoxyisobutyl isonitrile in acute myocardial infarction before and after thrombolytic treatment. assessment of salvaged myocardium and prediction of late functional recovery. J Am Coll Cardiol 1990;150:301-14
3. Gibbons RJ, Holmes DR, Reeder GS, Bailey KR, Hopfenspinger MR, Gersh BJ Immediate angioplasty compared with the administration of thrombolytic agent followed by conservative treatment for myocardial infarction. The Mayo Coronary Care Unit and Catheterization Laboratory Groups. N Engl J Med 1993;328:685-91
4. Schomig A, Kastrati A, Dirschinger J, Mehilli J, Schricke U, Pache J, Martinoff S, Neumann FJ, Schwaiger M Coronary stenting plus platelet glycoprotein IIb/IIIa blockade compared with tissue plasminogen activator in acute myocardial infarction. Stent versus Thrombolysis for Occluded Coronary Arteries in Patients with Acute Myocardial Infarction Study Investigators. N Engl J Med 2000;343:385-91
5. Kastrati A, Mehilli J, Dirschinger J, Schricke U, Neverve J, Pache J, Martinoff S, Neumann FJ, Nekolla S, Blasini R, Seyfarth M, Schwaiger M, Schomig A; Stent versus Thrombolysis for Occluded Coronary Arteries in Patients With Acute Myocardial Infarction (STOPAMI-2) Study. Myocardial salvage after coronary stenting plus abciximab versus fibrinolysis plus abciximab in patients with acute myocardial infarction: a randomised trial Lancet 2002;359:920-25
6. Germano G, Erel J, Lewin H, Kavanagh PB, Berman DS. Automatic quantitation of regional myocardial wall motion and thickening from gated technetium-99m sestamibi myocardial perfusion single-photon emission computed tomography. J Am Coll Cardiol 1997;30:1360-67
7. Mansoor MR, Heller GV. Gated SPECT imaging. Semin Nucl Med 1999;29:271-78
8. Castro PF, Corbalan R, Baeza R, Nazzal C, Greig DP, Miranda FP, Gonzalez R, Marchant E, Olea E, Larrain G. Effect of primary coronary angioplasty on left ventricular function and myocardial perfusion as determined by Tc-99m sestamibi scintigraphy. Am J Cardiol 2001;87:1181-84
9. Brodie BR, Stuckey TD, Hansen C, Muncy D Benefit of coronary reperfusion before intervention on outcomes after primary angioplasty for acute myocardial infarction. Am J Cardiol 2000;85:13-8
10. Stone GW, Cox D, Garcia E, Brodie BR, Morice MC, Griffin J, Mattos L, Lansky AJ, O'Neill WW, Grines CL. Normal flow (TIMI 3) before mechanical reperfusion therapy is an independent determinant of survival in acute myocardial infarction. Analysis from the Primary Angioplasty in Myocardial Infarction trials. Circulation 2001;104:636-41
11. Ishihara M, Inoue I, Kawagoe T, Shimatani Y, Kunsu S, Nishioka K, Umemura T, Nakamura S, Yoshida M Impact of spontaneous anterograde flow of the infarct artery on left ventricular function in patients with a first anterior wall acute myocardial infarction. Am J Cardiol 2002;90.5-9
12. Clements IP, Christian TF, Higano ST, Gibbons RJ, Gersh BJ. Residual flow to the infarct zone as a determinant of infarct size after direct angioplasty. Circulation 1993;88:1527-33
13. The TIMI Study Group. The Thrombolysis in Myocardial Infarction (TIMI) trial: phase 1 findings N Engl J Med 1985;312:932-36
14. Poli A, Fetiveau R, Vandom P, del Rosso G, D'Urbano M, Seveso G, Cafiero F, De Servi S. Integrated analysis of myocardial blush and ST-segment elevation recovery after successful primary angioplasty. Real-time grading of microvascular reperfusion and prediction of early and late recovery of left ventricular function. Circulation 2002;106:313-18
15. Segar D, Brown SE, Sawada SG, Ryan T, Feigenbaum H. Dobutamine stress echocardiography: correlation with coronary lesion seventy as determined by quantitative angiography. J Am Coll Cardiol 1992;19:1197-1202
16. Chua T, Kiat H, Germano G, Maurer G, van Train K, Friedman J, Berman D Gated technetium-99m sestamibi for simultaneous assessment of stress myocardial perfusion, postexercise regional ventricular function and myocardial viability Correlation with echocardiography and rest thallium-201 scintigraphy. J Am Coll Cardiol 1994;23:1107-14
17. Leoncini M, Marcucci G, Sciagrà R, Frascarelli F, Traini AM, Mondanelli D, Magni M, Bini L, Bellandi F, Mennuti A, Dabizzi RP. Nitrate-enhanced gated Tc-99m sestamibi SPECT for evaluating regional wall motion at baseline and during low dose dobutamine infusion in patients with chronic coronary artery disease and left ventricular dysfunction. Comparison with two-dimensional echocardiography. J Nucl Cardiol 2000;7:426-31
18. Leoncini M, Marcucci G, Sciagrà R, Frascarelli F, Simonetti I, Bini L, Maioli M, Mennuti A, Dabizzi RP. Prediction of functional recovery in patients with chronic coronary artery disease and left ventricular dysfunction combining the evaluation of myocardial perfusion and contractile reserve using nitrate-enhanced technetium-99m sestamibi gated single-photon emission computed tomography and dobutamine stress. Am J Cardiol 2001;87:1346-50
19. Meluzin J, Cerny J, Frelich M, Stetka F, Spinarova L, Popelova J, Stipal R. Prognostic value of the amount of dysfunctional but viable myocardium in revascularized patients with coronary artery disease and left ventricular dysfunction. J Am Coll Cardiol 1998;32:912-20
20. Montalescot G, Barragan P, Wittenberg O, Ecollan P, Elhadad S, Villain P, Boulenc JM, Morice MC, Maillard L, Pansieri M, Choussat R, Pinton P; ADMIRAL Investigators. Abciximab before direct angioplasty and stenting in myocardial infarction regarding acute and long-term follow-up. Platelet glycoprotein IIb/IIIa inhibitors with coronary stenting for acute myocardial infarction. N Engl J Med 2001;1344:1895-1903
21. Hamada S, Nishiue T, Nakamura S, Sugiura T, Kamihata H, Miyoshi H, Imuro Y, Iwasaka T. TIMI frame count immediately after primary coronary angioplasty as a predictor of functional recovery in patients with TIMI 3 reperfused acute myocardial infarction. J Am Coll Cardiol 2001;38:666-71
22. Gibbons RJ, Christian TF, Hopfenspringer M, Hodge DO, Bailey KR Myocardium at risk and infarct size after thrombolytic therapy for acute myocardial infarction: implications for the design of randomized trial of acute interventions. J Am Coll Cardiol 1994;24:616-23
23. Touboul P, Andre-Fouet X, Leizorovicz A, Itti R, Lopez M, Sayegh Y, Milon H, Kirkorian G Risk stratification after myocardial infarction. A reappraisal in the era of thrombolysis. The Groupe d'Etude du Pronostic de l'Infarctus du Myocarde (GREPI). Eur Heart J 1997;18:99-107
24. Sharir T, Germano G, Kavanagh PB, Lai S, Cohen I, Lewin HC, Friedman JD, Zellweger MJ, Berman DS. Incremental prognostic value of post-stress left ventricular ejection fraction and volume by gated myocardial perfusion single photon emission computed tomography. Circulation 1999;100:1035-42
25. Bolognese L, Carrabba N, Parodi G, Santoro GM, Buonamici P, Cerisano G, Antoniucci D. Impact of microvascular dysfunction on left ventricular remodeling and long-term clinical outcome after primary coronary angioplasty for acute myocardial infarction. Circulation 2004;109:1121-26
26. 99mTc-sestamibi myocardial SPECT. J Nucl Med 2001;42:695-700
27. Cullom SJ, Case JA, Bateman TM. Electrocardiographically gated myocardial perfusion SPECT: technical principles and quality control considerations. J Nucl Cardiol 1998;5:418-25
28. 99mTc- sestamibi gated single-photon emission computed tomography in patients treated with primary percutaneous coronary intervention. Eur J Nucl Med Mol Imaging 2004 Mar 5 (Epub ahead of print) DOI 10.1007/s00259-004-1482-4
29. Johnson LL, Verdesca SA, Aude WY, Xavier RC, Nott LT, Campanella MW, Germano G. Postischemic stunning can affect left ventricular ejection fraction and regional wall motion on post-stress gated sestamibi tomograms. J Am Coll Cardiol 1997;30:1641-48
30. Christian TF, O'Connor MK, Glynn RB, Rogers PJ, Gibbons RJ. The influence of gating on measurements of myocardium at risk and infarct size during acute myocardial infarction by tomographic technetium 99m-labelled sestamibi imaging. J Nucl Cardiol 1995;2:207-16