Steroid degradation gene cluster of Comamonas testosteroni consisting of 18 putative genes from meta-cleavage enzyme gene tesB to regulator gene tesR

Biochemical and Biophysical Research Communications

Volumn 324, Issue 2, 2004, Pages 597-604

  Horinouchi, Masae ^a   Kurita, Tomokazu ^b   Yamamoto, Takako ^b   Hatori, Emi ^b   Hayashi, Toshiaki ^a   Kudo, Toshiaki ^a,c,d  

^a RIKEN   (Japan)

^b TOYO UNIVERSITY   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^d YOKOHAMA CITY UNIVERSITY   (Japan)

Author keywords

Comamonas testosteroni; Steroid; Testosterone

Indexed keywords

BACTERIAL ENZYME; OXIDOREDUCTASE; STEROID;

ARTICLE; BACTERIAL GENE; COMAMONAS TESTOSTERONI; DNA FLANKING REGION; GENE CLUSTER; GENE CONTROL; GENE IDENTIFICATION; GENE INDUCTION; GENETIC CODE; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PRIORITY JOURNAL; TESB GENE; TESR GENE; TRANSPOSON;

COMAMONAS TESTOSTERONI; TRANSPOSONS;

EID: 5444248632     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2004.09.096     Document Type: Article

References (25)

1. R.M. Dodson, and R.D. Muir Microbiological transformations. II. Microbiological aromatization of steroids J. Am. Chem. Soc. 80 1958 5004 5005
2. R.M. Dodson, and R.D. Muir Microbiological transformations. III. The hydroxylation of steroids at C-9 J. Am. Chem. Soc. 80 1958 6148
3. R.M. Dodson, and R.D. Muir Microbiological transformations. IV. The microbiological aromatization of steroids J. Am. Chem. Soc. 83 1961 4627 4631
4. C.J. Sih, and K.C. Wang Mechanisms of steroid oxidation by microorganisms. II. Isolation and characterization of 3aα-H-4α- [3′-propionic acid]-7aβ-methylhezahydro-1,5-indanedione J. Am. Chem. Soc. 85 1963 2135 2137
5. C.J. Sih, K.C. Wang, D.T. Gibson, and H.W.J. Whitlock On the mechanism of ring A cleavage in the degradation of 9,10-seco steroids by microorganisms J. Am. Chem. Soc. 87 1965 1386 1387
6. C.J. Sih, S.S. Lee, Y.K. Tsong, and K.C. Wang 3,4-Dihydroxy- 9,10-secoandrosta-1,3,5(10)-triene-9,17-dione. An intermediate in the microbiological degradation of ring A of androst-4-ene-3,17-dione J. Am. Chem. Soc. 87 1965 1385 1386
7. D.T. Gibson, K.C. Wang, C.J. Sih, and H. Whitlock Jr. Mechanisms of steroid oxidation by microorganisms. IX. On the mechanism of ring A cleavage in the degradation of 9,10-seco steroids by microorganisms J. Biol. Chem. 241 1966 551 559
8. C.J. Sih, S.S. Lee, Y.K. Tsong, and K.C. Wang Mechanisms of steroid oxidation by microorganisms. VIII. 3,4-Dihydroxy-9,10-secoandrosta-1,3,5(10)- triene-9,17-dione, an intermediate in the microbiological degradation of ring A of androst-4-ene-3,17-dione J. Biol. Chem. 241 1966 540 550
9. A.W. Coulter, and P. Talalay Studies on the microbial degradation of steroid ring A J. Biol. Chem. 243 1968 3238 3247
10. J.H. Abalain, S. Di Stefano, Y. Amet, E. Quemener, M.L. Abalain-Colloc, and H.H. Floch Cloning, DNA sequencing and expression of (3â€" 17)b hydroxysteroid dehydrogenase from Pseudomonas testosteroni J. Steroid Biochem. Mol. Biol. 44 1993 133 139
11. S. Genti-Raimondi, M.E. Tolmasky, L.C. Patrito, A. Flury, and L.A. Actis Molecular cloning and expression of the β-hydroxysteroid dehydrogenase gene from Pseudomonas testosteroni Gene 105 1991 43 49
12. J.E. Cabrera, J.L. Pruneda Paz, and S. Genti-Raimondi Steroid-inducible transcription of the 3β/17β-hydroxysteroid dehydrogenase gene (3β/17β-hsd) in Comamonas testosteroni J. Steroid Biochem. Mol. Biol. 73 2000 147 152
13. P. Plesiat, M. Grandguillot, S. Harayama, S. Vragar, and Y. Michel-Briand Cloning, sequencing, and expression of the Pseudomonas testosteroni gene encoding 3-oxosteroid Î"1-dehydrogenase J. Bacteriol. 173 1991 7219 7227
14. U.C. Oppermann, and E. Maser Characterization of a 3α- hydroxysteroid dehydrogenase/carbonyl reductase from the gram-negative bacterium Comamonas testosteroni Eur. J. Biochem. 241 1996 744 749
15. E. Mobus, and E. Maser Molecular cloning, overexpression, and characterization of steroid-inducible 3α-hydroxysteroid dehydrogenase/carbonyl reductase from Comamonas testosteroni. A novel member of the short-chain dehydrogenase/reductase superfamily J. Biol. Chem. 273 1998 30888 30896
16. E. Maser, E. Mobus, and G. Xiong Functional expression, purification, and characterization of 3α-hydroxysteroid dehydrogenase/carbonyl reductase from Comamonas testosteroni Biochem. Biophys. Res. Commun. 272 2000 622 628
17. E. Maser, G. Xiong, C. Grimm, R. Ficner, and K. Reuter 3α-Hydroxysteroid dehydrogenase/carbonyl reductase from Comamonas testosteroni: biological significance, three-dimensional structure and gene regulation Chem. Biol. Interact. 130â€"132 2001 707 722
18. G. Xiong, H. Martin, A. Blum, C. Schafers, and E. Maser A model on the regulation of 3α-hydroxysteroid dehydrogenase/carbonyl reductase expression in Comamonas testosteroni Chem. Biol. Interact. 130†"132 2001 723 736
19. G. Xiong, and E. Maser Regulation of the steroid-inducible 3α-hydroxysteroid dehydrogenase/carbonyl reductase gene in Comamonas testosteroni J. Biol. Chem. 276 2001 9961 9970
20. G. Xiong, S. Markowetz, and E. Maser Regulation of 3α- hydroxysteroid dehydrogenase/carbonyl reductase in Comamonas testosteroni: function and relationship of two operators Chem. Biol. Interact. 143â€"144 2003 411 423
21. G. Xiong, H.J. Martin, and E. Maser Identification and characterization of a novel translational repressor of the steroid-inducible 3α- hydroxysteroid dehydrogenase/carbonyl reductase gene in Comamonas testosteroni J. Biol. Chem. 278 2003 47400 47407
22. J.L. Pruneda-Paz, M. Linares, J.E. Cabrera, and S. Genti-Raimondi TeiR a LuxR-type transcription factor required for testosterone degradation in Comamonas testosteroni J. Bacteriol. 186 2004 1430 1437
23. M. Horinouchi, T. Yamamoto, K. Taguchi, H. Arai, and T. Kudo Meta-cleavage enzyme gene tesB is necessary for testosterone degradation in Comamonas testosteroni TA441 Microbiology 147 2001 3367 3375
24. M. Horinouchi, T. Hayashi, H. Koshino, T. Yamamoto, and T. Kudo Gene encoding the hydrolase for the product of the meta-cleavage reaction in testosterone degradation by Comamonas testosteroni Appl. Environ. Microbiol. 69 2003 2139 2152
25. M. Horinouchi, T. Hayashi, T. Yamamoto, and T. Kudo A new bacterial steroid degradation gene cluster which consists of aromatic compound degradation genes for seco-steroids and 3-ketosteroid dehydrogenase genes in Comamonas testosteroni TA441 Appl. Environ. Microbiol. 69 2003 4421 4430