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Volumn 3, Issue 1, 2004, Pages 29-34

Mitochondrial influence on aging rate in Caenorhabditis elegans

Author keywords

Aging; C. elegans; Coenzyme Q; Longevity; Mitochondria; Ubiquinone

Indexed keywords

ANTIMYCIN A1; REACTIVE OXYGEN METABOLITE; UBIQUINONE; CAENORHABDITIS ELEGANS PROTEIN; CLK 1 PROTEIN, C ELEGANS; CLK-1 PROTEIN, C ELEGANS;

EID: 5444247439     PISSN: 14749718     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1474-9728.2003.00077.x     Document Type: Review
Times cited : (25)

References (38)
  • 1
    • 0037127026 scopus 로고    scopus 로고
    • Regulation of life-span by germ-line stem cells in Caenorhabditis elegans
    • Arantes-Oliveira N, Apfeld J, Dillin A, Kenyon C (2002) Regulation of life-span by germ-line stem cells in Caenorhabditis elegans. Science 295, 502-505.
    • (2002) Science , vol.295 , pp. 502-505
    • Arantes-Oliveira, N.1    Apfeld, J.2    Dillin, A.3    Kenyon, C.4
  • 2
    • 0033529032 scopus 로고    scopus 로고
    • Apparent uncoupling of energy production and consumption in long-lived Clk mutants of Caenorhabditis elegans
    • Braeckman BP, Houthoofd K, De Vreese A, Vanfleteren JR (1999) Apparent uncoupling of energy production and consumption in long-lived Clk mutants of Caenorhabditis elegans. Curr. Biol. 9, 493-496.
    • (1999) Curr. Biol. , vol.9 , pp. 493-496
    • Braeckman, B.P.1    Houthoofd, K.2    De Vreese, A.3    Vanfleteren, J.R.4
  • 3
    • 0036236006 scopus 로고    scopus 로고
    • The mitochondrial-lysosomal axis theory of aging: Accumulation of damaged mitochondria as a result of imperfect autophagocytosis
    • Brunk UT, Terman A (2002) The mitochondrial-lysosomal axis theory of aging: accumulation of damaged mitochondria as a result of imperfect autophagocytosis. Eur. J. Biochem. 269, 1996-2002.
    • (2002) Eur. J. Biochem. , vol.269 , pp. 1996-2002
    • Brunk, U.T.1    Terman, A.2
  • 4
    • 0017643661 scopus 로고
    • The aging process of the nematode Caenorhabditis elegans in bacterial and axenic culture
    • Croll NA, Smith JM, Zuckerman BM (1977) The aging process of the nematode Caenorhabditis elegans in bacterial and axenic culture. Exp. Aging Res. 3, 175-189.
    • (1977) Exp. Aging Res. , vol.3 , pp. 175-189
    • Croll, N.A.1    Smith, J.M.2    Zuckerman, B.M.3
  • 5
    • 0036198149 scopus 로고    scopus 로고
    • Multiple stressors in Caenorhabditis elegans induce stress hormesis and extended longevity
    • Cypser JR, Johnson TE (2002) Multiple stressors in Caenorhabditis elegans induce stress hormesis and extended longevity. J. Gerontol. A Biol. Sci. Med. Sci. 57, B109-B114.
    • (2002) J. Gerontol. A. Biol. Sci. Med. Sci. , vol.57
    • Cypser, J.R.1    Johnson, T.E.2
  • 7
    • 0031030678 scopus 로고    scopus 로고
    • Structural and functional conservation of the Caenorhabditis elegans timing gene clk-l
    • Ewbank JJ, Barnes TM, Lakowski B, Lussier M, Bussey H, Hekimi S (1997) Structural and functional conservation of the Caenorhabditis elegans timing gene clk-l. Science 275, 980-983.
    • (1997) Science , vol.275 , pp. 980-983
    • Ewbank, J.J.1    Barnes, T.M.2    Lakowski, B.3    Lussier, M.4    Bussey, H.5    Hekimi, S.6
  • 8
    • 0033118981 scopus 로고    scopus 로고
    • CLK-1 controls respiration, behavior and aging in the nematode Caenorhabditis elegans
    • Felkai S, Ewbank JJ, Lemieux J, Labbe JC, Brown GG, Hekimi S (1999) CLK-1 controls respiration, behavior and aging in the nematode Caenorhabditis elegans. EMBO J. 18, 1783-1792.
    • (1999) EMBO J. , vol.18 , pp. 1783-1792
    • Felkai, S.1    Ewbank, J.J.2    Lemieux, J.3    Labbe, J.C.4    Brown, G.G.5    Hekimi, S.6
  • 9
    • 0035515923 scopus 로고    scopus 로고
    • Mitochondrial electron transport is a key determinant of life span in Caenorhabditis elegans
    • Feng J, Bussiere F, Hekimi S (2001) Mitochondrial electron transport is a key determinant of life span in Caenorhabditis elegans. Dev. Cell 1, 633-644.
    • (2001) Dev. Cell , vol.1 , pp. 633-644
    • Feng, J.1    Bussiere, F.2    Hekimi, S.3
  • 10
    • 0031081410 scopus 로고    scopus 로고
    • A proposed refinement of the mitochondrial free radical theory of aging
    • de Grey AD (1997) A proposed refinement of the mitochondrial free radical theory of aging. Bioessays 19, 161-166.
    • (1997) Bioessays , vol.19 , pp. 161-166
    • de Grey, A.D.1
  • 11
    • 0015319592 scopus 로고
    • The biologic clock: The mitochondria?
    • Harman D (1972) The biologic clock: the mitochondria? J. Am. Geriatr. Soc. 20, 145-147.
    • (1972) J. Am. Geriatr. Soc. , vol.20 , pp. 145-147
    • Harman, D.1
  • 12
    • 0036975161 scopus 로고    scopus 로고
    • Axenic growth up-regulates mass-specific metabolic rate, stress resistance, and extends life span in Caenorhabditis elegans
    • Houthoofd K, Braeckman BP, Lenaerts I, Brys K, De Vreese A, Van Eygen S, Vanfleteren JR (2002) Axenic growth up-regulates mass-specific metabolic rate, stress resistance, and extends life span in Caenorhabditis elegans. Exp. Gerontol. 37, 1371-1378.
    • (2002) Exp. Gerontol. , vol.37 , pp. 1371-1378
    • Houthoofd, K.1    Braeckman, B.P.2    Lenaerts, I.3    Brys, K.4    De Vreese, A.5    Van Eygen, S.6    Vanfleteren, J.R.7
  • 15
    • 0021686137 scopus 로고
    • Arresting development arrests aging in the nematode Caenorhabditis elegans
    • Johnson TE, Mitchell DH, Kline S, Kemal R, Foy J (1984) Arresting development arrests aging in the nematode Caenorhabditis elegans. Mech. Ageing Dev. 28, 23-40.
    • (1984) Mech. Ageing Dev. , vol.28 , pp. 23-40
    • Johnson, T.E.1    Mitchell, D.H.2    Kline, S.3    Kemal, R.4    Foy, J.5
  • 16
    • 0019480519 scopus 로고
    • Monitoring of relative mitochondrial membrane potential in living cells by fluorescence microscopy
    • Johnson LV, Walsh ML, Bockus BJ, Chen LB (1981) Monitoring of relative mitochondrial membrane potential in living cells by fluorescence microscopy. J. Cell Biol. 88, 526-535.
    • (1981) J. Cell Biol. , vol.88 , pp. 526-535
    • Johnson, L.V.1    Walsh, M.L.2    Bockus, B.J.3    Chen, L.B.4
  • 17
    • 0345803002 scopus 로고    scopus 로고
    • Reproductive fitness and quinone content of C. elegans clk-1 mutants fed coenzyme Q isoforms of varying length
    • in press
    • Jonassen T, Davis DE, Larsen PL, Clarke CF (2003) Reproductive fitness and quinone content of C. elegans clk-1 mutants fed coenzyme Q isoforms of varying length. J. Biol. Chem. 6, in press.
    • (2003) J. Biol. Chem. , vol.6
    • Jonassen, T.1    Davis, D.E.2    Larsen, P.L.3    Clarke, C.F.4
  • 18
    • 0035895199 scopus 로고    scopus 로고
    • A dietary source of coenzyme Q is essential for growth of long-lived Caenorhabditis elegans clk-l mutants
    • Jonassen T, Larsen PL, Clarke CF (2001) A dietary source of coenzyme Q is essential for growth of long-lived Caenorhabditis elegans clk-l mutants. Proc. Natl Acad. Sci. USA 98, 421-426.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 421-426
    • Jonassen, T.1    Larsen, P.L.2    Clarke, C.F.3
  • 20
    • 0027771804 scopus 로고
    • A C. elegans mutant that lives twice as long as wild-type
    • Kenyon C, Chang J, Gensch E, Rudner A, Tabtiang R. (1993) A C. elegans mutant that lives twice as long as wild-type. Nature 366, 461-464.
    • (1993) Nature , vol.366 , pp. 461-464
    • Kenyon, C.1    Chang, J.2    Gensch, E.3    Rudner, A.4    Tabtiang, R.5
  • 21
    • 2442692102 scopus 로고    scopus 로고
    • Hydroxyurea arrests DNA replication by a mechanism that preserves basal dNTP pools
    • in press
    • Koc A, Wheeler LJ, Mathews CK, Merrill GF (2003) Hydroxyurea arrests DNA replication by a mechanism that preserves basal dNTP pools. J. Biol. Chem. 21, in press.
    • (2003) J. Biol. Chem. , vol.21
    • Koc, A.1    Wheeler, L.J.2    Mathews, C.K.3    Merrill, G.F.4
  • 22
    • 0029776793 scopus 로고    scopus 로고
    • Determination of life-span in Caenorhabditis elegans by four clock genes
    • Lakowski B, Hekimi S (1996) Determination of life-span in Caenorhabditis elegans by four clock genes. Science 272, 1010-1013.
    • (1996) Science , vol.272 , pp. 1010-1013
    • Lakowski, B.1    Hekimi, S.2
  • 23
    • 0037016442 scopus 로고    scopus 로고
    • Extension of life-span in Caenorhabditis elegans by a diet lacking coenzyme Q
    • Larsen PL, Clarke CF (2002) Extension of life-span in Caenorhabditis elegans by a diet lacking coenzyme Q. Science 295, 120-123.
    • (2002) Science , vol.295 , pp. 120-123
    • Larsen, P.L.1    Clarke, C.F.2
  • 24
    • 0037228016 scopus 로고    scopus 로고
    • A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity
    • Lee SS, Lee RY, Fraser AG, Kamath RS, Ahringer J, Ruvkun G (2003) A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity. Nat. Genet. 33, 40-48.
    • (2003) Nat. Genet. , vol.33 , pp. 40-48
    • Lee, S.S.1    Lee, R.Y.2    Fraser, A.G.3    Kamath, R.S.4    Ahringer, J.5    Ruvkun, G.6
  • 25
    • 0029123058 scopus 로고
    • Thermotolerance and extended life-span conferred by single-gene mutations and induced by thermal stress
    • Lithgow GJ, White TM, Melov S, Johnson TE (1995) Thermotolerance and extended life-span conferred by single-gene mutations and induced by thermal stress. Proc. Natl Acad. Sci. USA 92, 7540-7544.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 7540-7544
    • Lithgow, G.J.1    White, T.M.2    Melov, S.3    Johnson, T.E.4
  • 26
    • 0022346645 scopus 로고
    • Characterization of the deoxynucleoside-dependent reversal of hypoxia-induced inhibition of cell cycle progression in Ehrlich ascites tumor cells
    • Loffler M (1985) Characterization of the deoxynucleoside-dependent reversal of hypoxia-induced inhibition of cell cycle progression in Ehrlich ascites tumor cells. Eur. J. Cell Biol. 39, 198-204.
    • (1985) Eur. J. Cell Biol. , vol.39 , pp. 198-204
    • Loffler, M.1
  • 27
    • 0042691506 scopus 로고    scopus 로고
    • Autophagy genes are essential for dauer development and life-span extension in C. elegans
    • Melendez A, Talloczy Z, Seaman M, Eskelinen EL, Hall DH, Levine B (2003) Autophagy genes are essential for dauer development and life-span extension in C. elegans. Science 301, 1387-1391.
    • (2003) Science , vol.301 , pp. 1387-1391
    • Melendez, A.1    Talloczy, Z.2    Seaman, M.3    Eskelinen, E.L.4    Hall, D.H.5    Levine, B.6
  • 29
    • 0030014296 scopus 로고    scopus 로고
    • A genetic pathway conferring life extension and resistance to UV stress in Caenorhabditis elegans
    • Murakami S, Johnson TE (1996) A genetic pathway conferring life extension and resistance to UV stress in Caenorhabditis elegans. Genetics 143, 1207-1218.
    • (1996) Genetics , vol.143 , pp. 1207-1218
    • Murakami, S.1    Johnson, T.E.2
  • 30
    • 0037771389 scopus 로고    scopus 로고
    • Are mitochondria a spontaneous and permanent source of reactive oxygen species?
    • Nohl H, Gille L, Kozlov A, Staniek K (2003) Are mitochondria a spontaneous and permanent source of reactive oxygen species? Redox Rep. 8, 135-141.
    • (2003) Redox Rep. , vol.8 , pp. 135-141
    • Nohl, H.1    Gille, L.2    Kozlov, A.3    Staniek, K.4
  • 31
    • 0034661024 scopus 로고    scopus 로고
    • Superoxides from mitochondrial complex III: The role of manganese superoxide dismutase
    • Raha S, McEachern GE, Myint AT, Robinson BH (2000) Superoxides from mitochondrial complex III: the role of manganese superoxide dismutase. Free Radic. Biol. Med. 29, 170-180.
    • (2000) Free Radic. Biol. Med. , vol.29 , pp. 170-180
    • Raha, S.1    McEachern, G.E.2    Myint, A.T.3    Robinson, B.H.4
  • 32
    • 0041440219 scopus 로고    scopus 로고
    • A metabolic model for life span determination in Caenorhabditis elegans
    • Rea S, Johnson TE (2003) A metabolic model for life span determination in Caenorhabditis elegans. Dev. Cell 5, 197-203.
    • (2003) Dev. Cell , vol.5 , pp. 197-203
    • Rea, S.1    Johnson, T.E.2
  • 33
    • 0035834789 scopus 로고    scopus 로고
    • A defect in the cytochrome b large subunit in complex II causes both superoxide anion overproduction and abnormal energy metabolism in Caenorhabditis elegans
    • Senoo-Matsuda N, Yasuda K, Tsuda M, Ohkubo T, Yoshimura S, Nakazawa H, Hartman PS, Ishii N (2001) A defect in the cytochrome b large subunit in complex II causes both superoxide anion overproduction and abnormal energy metabolism in Caenorhabditis elegans. J. Biol. Chem. 276, 41 553-41 558.
    • (2001) J. Biol. Chem. , vol.276 , pp. 41553-41558
    • Senoo-Matsuda, N.1    Yasuda, K.2    Tsuda, M.3    Ohkubo, T.4    Yoshimura, S.5    Nakazawa, H.6    Hartman, P.S.7    Ishii, N.8
  • 34
    • 0035823556 scopus 로고    scopus 로고
    • A new member of the family of di-iron carboxylate proteins. Coq7 (clk-1), a membrane-bound hydroxylase involved in ubiquinone biosynthesis
    • Stenmark P, Grunler J, Mattsson J, Sindelar PJ, Nordlund P, Berthold DA (2001) A new member of the family of di-iron carboxylate proteins. Coq7 (clk-1), a membrane-bound hydroxylase involved in ubiquinone biosynthesis. J. Biol. Chem. 276, 33297-33300.
    • (2001) J. Biol. Chem. , vol.276 , pp. 33297-33300
    • Stenmark, P.1    Grunler, J.2    Mattsson, J.3    Sindelar, P.J.4    Nordlund, P.5    Berthold, D.A.6
  • 35
    • 0035941485 scopus 로고    scopus 로고
    • Ingestion of bacterially expressed dsRNAs can produce specific and potent genetic interference in Caenorhabditis elegans
    • Timmons L, Court DL, Fire A (2001) Ingestion of bacterially expressed dsRNAs can produce specific and potent genetic interference in Caenorhabditis elegans. Gene 263, 103-112.
    • (2001) Gene , vol.263 , pp. 103-112
    • Timmons, L.1    Court, D.L.2    Fire, A.3
  • 36
    • 0033832593 scopus 로고    scopus 로고
    • Broad oxygen tolerance in the nematode Caenorhabditis elegans
    • Van Voorhies WA, Ward S (2000) Broad oxygen tolerance in the nematode Caenorhabditis elegans. J. Exp. Biol. 203, 2467-2478.
    • (2000) J. Exp. Biol. , vol.203 , pp. 2467-2478
    • Van Voorhies, W.A.1    Ward, S.2
  • 37
    • 0034613164 scopus 로고    scopus 로고
    • Regulation of C. elegans life-span by insulinlike signaling in the nervous system
    • Wolkow CA, Kimura KD, Lee MS, Ruvkun G (2000) Regulation of C. elegans life-span by insulinlike signaling in the nervous system. Science 290, 147-150.
    • (2000) Science , vol.290 , pp. 147-150
    • Wolkow, C.A.1    Kimura, K.D.2    Lee, M.S.3    Ruvkun, G.4
  • 38
    • 0028950419 scopus 로고
    • Mutations in the clk-1 gene of Caenorhabditis elegans affect developmental and behavioral timing
    • Wong A, Boutis P, Hekimi S (1995) Mutations in the clk-1 gene of Caenorhabditis elegans affect developmental and behavioral timing. Genetics 139, 1247-1259.
    • (1995) Genetics , vol.139 , pp. 1247-1259
    • Wong, A.1    Boutis, P.2    Hekimi, S.3


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