Native E2F/RBF complexes contain Myb-interacting proteins and repress transcription of developmentally controlled E2F target genes

Cell

Volumn 119, Issue 2, 2004, Pages 181-193

  Korenjak, Michael ^a   Taylor Harding, Barbie ^b   Binné, Ulrich K ^b   Satterlee, John S ^b   Stevaux, Olivier ^b   Aasland, Rein ^c   White Cooper, Helen ^d   Dyson, Nick ^b   Brehm, Alexander ^a  

^a UNIVERSITY OF MUNICH   (Germany)

^b MASSACHUSETTS GENERAL HOSPITAL CANCER CENTER   (United States)

^c UNIVERSITY OF BERGEN   (Norway)

^d UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

RETINOBLASTOMA PROTEIN; TRANSCRIPTION FACTOR E2F;

ANIMAL CELL; ARTICLE; CAENORHABDITIS ELEGANS; CELL DIFFERENTIATION; CHROMATIN STRUCTURE; CONTROLLED STUDY; DNA REPLICATION; DROSOPHILA; EMBRYO; GENE CONTROL; GENE REPRESSION; GENE TARGETING; GENETIC TRANSCRIPTION; NONHUMAN; ONCOGENE MYB; OVARY FOLLICLE CELL; POLYTENE CHROMOSOME; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN PURIFICATION; SPEECH ARTICULATION; TISSUE DIFFERENTIATION; TRANSCRIPTION REGULATION; VULVA;

ANIMALIA; CAENORHABDITIS; CAENORHABDITIS ELEGANS; DROSOPHILA;

EID: 5444237176     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cell.2004.09.034     Document Type: Article

References (46)

1. Aggarwal B.D., Calvi B.R. Chromatin regulates origin activity in Drosophila follicle cells. Nature. 430:2004;372-376
2. Ait-Si-Ali S., Guasconi V., Fritsch L., Yahi H., Sekhri R., Naguibneva I., Robin P., Cabon F., Polesskaya A., Harel-Bellan A. A Suv39h-dependent mechanism for silencing S-phase genes in differentiating but not in cycling cells. EMBO J. 23:2004;605-615
3. Angus S.P., Mayhew C.N., Solomon D.A., Braden W.A., Markey M.P., Okuno Y., Cardoso M.C., Gilbert D.M., Knudsen E.S. RB reversibly inhibits DNA replication via two temporally distinct mechanisms. Mol. Cell. Biol. 24:2004;5404-5420
4. Avni D., Yang H., Martelli F., Hofmann F., ElShamy W.M., Ganesan S., Scully R., Livingston D.M. Active localization of the retinoblastoma protein in chromatin and its response to S phase DNA damage. Mol. Cell. 12:2003;735-746
5. Beall E.L., Manak J.R., Zhou S., Bell M., Lipsick J.S., Botchan M.R. Role for a Drosophila Myb-containing protein complex in site-specific DNA replication. Nature. 420:2002;833-837
6. Beall, E.L., Bell, M., Georlette, D., and Botchan, M.R. (2004). Myb mutant lethality in Drosophila is dependent upon Mip130: positive and negative regulation of DNA replication. Genes Dev.
7. Becker P.B., Hörz W. ATP-dependent nucleosome remodeling. Annu. Rev. Biochem. 71:2002;247-273
8. Bosco G., Du W., Orr-Weaver T.L. DNA replication control through interaction of E2F-RB and the origin recognition complex. Nat. Cell Biol. 3:2001;289-295
9. Bouazoune K., Mitterweger A., Langst G., Imhof A., Akhtar A., Becker P.B., Brehm A. The dMi-2 chromodomains are DNA binding modules important for ATP-dependent nucleosome mobilization. EMBO J. 21:2002;2430-2440
10. Calvi B.R., Lilly M.A., Spradling A.C. Cell cycle control of chorion gene amplification. Genes Dev. 12:1998;734-744
11. Cam H., Dynlacht B.D. Emerging roles for E2F. beyond the G1/S transition and DNA replication Cancer Cell. 3:2003;311-316
12. Cayirlioglu P., Bonnette P.C., Dickson M.R., Duronio R.J. Drosophila E2f2 promotes the conversion from genomic DNA replication to gene amplification in ovarian follicle cells. Development. 128:2001;5085-5098
13. Ceol C.J., Horvitz H.R. dpl-1 DP and efl-1 E2F act with lin-35 Rb to antagonize Ras signaling in C. elegans vulval development. Mol. Cell. 7:2001;461-473
14. Ceol C.J., Horvitz H.R. A new class of C. elegans synMuv genes implicates a Tip60/NuA4-like HAT complex as a negative regulator of Ras signaling. Dev. Cell. 6:2004;563-576
15. Clarke A.R., Maandag E.R., van Roon M., van der Lugt N.M., van der Valk M., Hooper M.L., Berns A., te Riele H. Requirement for a functional Rb-1 gene in murine development. Nature. 359:1992;328-330
16. Cloud J.E., Rogers C., Reza T.L., Ziebold U., Stone J.R., Picard M.H., Caron A.M., Bronson R.T., Lees J.A. Mutant mouse models reveal the relative roles of E2F1 and E2F3 in vivo. Mol. Cell. Biol. 22:2002;2663-2672
17. DeGregori J. The genetics of the E2F family of transcription factors. shared functions and unique roles Biochim. Biophys. Acta. 1602:2002;131-150
18. Dimova D.K., Stevaux O., Frolov M.V., Dyson N.J. Cell cycle-dependent and cell cycle-independent control of transcription by the Drosophila E2F/RB pathway. Genes Dev. 17:2003;2308-2320
19. Frolov M.V., Dyson N.J. Molecular mechanisms of E2F-dependent activation and pRB-mediated repression. J. Cell Sci. 117:2004;2173-2181
20. Frolov M.V., Huen D.S., Stevaux O., Dimova D., Balczarek-Strang K., Elsdon M., Dyson N.J. Functional antagonism between E2F family members. Genes Dev. 15:2001;2146-2160
21. Frolov M.V., Stevaux O., Moon N.S., Dimova D., Kwon E.J., Morris E.J., Dyson N.J. G1 cyclin-dependent kinases are insufficient to reverse dE2F2-mediated repression. Genes Dev. 17:2003;723-728
22. Jacks T., Fazeli A., Schmitt E.M., Bronson R.T., Goodell M.A., Weinberg R.A. Effects of an Rb mutation in the mouse. Nature. 359:1992;295-300
23. Joaquin M., Bessa M., Saville M.K., Watson R.J. B-Myb overcomes a p107-mediated cell proliferation block by interacting with an N-terminal domain of p107. Oncogene. 21:2002;7923-7932
24. Kennedy B.K., Barbie D.A., Classon M., Dyson N., Harlow E. Nuclear organization of DNA replication in primary mammalian cells. Genes Dev. 14:2000;2855-2868
25. Knudsen E.S., Buckmaster C., Chen T.T., Feramisco J.R., Wang J.Y. Inhibition of DNA synthesis by RB. effects on G1/S transition and S-phase progression Genes Dev. 12:1998;2278-2292
26. Lee E.Y., Chang C.Y., Hu N., Wang Y.C., Lai C.C., Herrup K., Lee W.H., Bradley A. Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis. Nature. 359:1992;288-294
27. Lee M.H., Williams B.O., Mulligan G., Mukai S., Bronson R.T., Dyson N., Harlow E., Jacks T. Targeted disruption of p107. functional overlap between p107 and Rb Genes Dev. 10:1996;1621-1632
28. Lindeman G.J., Dagnino L., Gaubatz S., Xu Y., Bronson R.T., Warren H.B., Livingston D.M. A specific, nonproliferative role for E2F-5 in choroid plexus function revealed by gene targeting. Genes Dev. 12:1998;1092-1098
29. Lu X., Horvitz H.R. lin-35 and lin-53, two genes that antagonize a C. elegans Ras pathway, encode proteins similar to Rb and its binding protein RbAp48. Cell. 95:1998;981-991
30. Narita M., Nunez S., Heard E., Lin A.W., Hearn S.A., Spector D.L., Hannon G.J., Lowe S.W. Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence. Cell. 113:2003;703-716
31. Nicolas E., Morales V., Magnaghi-Jaulin L., Harel-Bellan A., Richard-Foy H., Trouche D. RbAp48 belongs to the histone deacetylase complex that associates with the retinoblastoma protein. J. Biol. Chem. 275:2000;9797-9804
32. Owen A.B., Stuart J., Mach K., Villeneuve A.M., Kim S. A gene recommender algorithm to identify coexpressed genes in C. elegans. Genome Res. 13:2003;1828-1837
33. Qian Y.W., Wang Y.C., Hollingsworth R.E. Jr., Jones D., Ling N., Lee E.Y. A retinoblastoma-binding protein related to a negative regulator of Ras in yeast. Nature. 364:1993;648-652
34. Royzman I., Austin R.J., Bosco G., Bell S.P., Orr-Weaver T.L. ORC localization in Drosophila follicle cells and the effects of mutations in dE2F and dDP. Genes Dev. 13:1999;827-840
35. Schneider R., Bannister A.J., Kouzarides T. Unsafe SETs. histone lysine methyltransferases and cancer Trends Biochem. Sci. 27:2002;396-402
36. Shen W.H. The plant E2F-Rb pathway and epigenetic control. Trends Plant Sci. 7:2002;505-511
37. Stevaux O., Dyson N.J. A revised picture of the E2F transcriptional network and RB function. Curr. Opin. Cell Biol. 14:2002;684-691
38. Stevaux O., Dimova D., Frolov M.V., Taylor-Harding B., Morris E., Dyson N. Distinct mechanisms of E2F regulation by Drosophila RBF1 and RBF2. EMBO J. 21:2002;4927-4937
39. Storre J., Elsasser H.P., Fuchs M., Ullmann D., Livingston D.M., Gaubatz S. Homeotic transformations of the axial skeleton that accompany a targeted deletion of E2f6. EMBO Rep. 3:2002;695-700
40. Sullivan W., Ashburner M., Hawley R.S. Drosophila Protocols. 2000;Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
41. Taylor-Harding B., Binne U.K., Korenjak M., Brehm A., Dyson N.J. p55, the Drosophila ortholog of RbAp46/RbAp48, is required for the repression of dE2F2/RBF-related genes. Mol. Cell. Biol. 24:2004;9124-9136
42. Trimarchi J.M., Lees J.A. Sibling rivalry in the E2F family. Nat. Rev. Mol. Cell Biol. 3:2002;11-20
43. Walhout A.J., Sordella R., Lu X., Hartley J.L., Temple G.F., Brasch M.A., Thierry-Mieg N., Vidal M. Protein interaction mapping in C. elegans using proteins involved in vulval development. Science. 287:2000;116-122
44. Weinberg R.A. The retinoblastoma protein and cell cycle control. Cell. 81:1995;323-330
45. White-Cooper H., Leroy D., MacQueen A., Fuller M.T. Transcription of meiotic cell cycle and terminal differentiation genes depends on a conserved chromatin associated protein, whose nuclear localisation is regulated. Development. 127:2000;5463-5473
46. Zhang H.S., Dean D.C. Rb-mediated chromatin structure regulation and transcriptional repression. Oncogene. 20:2001;3134-3138