Synthesis and characterization of a new series of hydroxy pyrazolines

Synthetic Communications

Volumn 38, Issue 22, 2008, Pages 3973-3983

  Parveen, Humaira ^a   Iqbal, Prince Firdoos ^a   Azam, Amir ^a  

^a JAMIA MILLIA ISLAMIA CENTRAL UNIVERSITY   (India)

Author keywords

Chalcone; Chalcone dibromide; Hydroxy pyrazoline; Pyrazoline

Indexed keywords

3 PHENYL 1 (THIOPHEN 2 YL)PROP 2 EN 1 ONE; ALCOHOL; BENZALDEHYDE; PYRAZOLINE DERIVATIVE; THIOPHENE DERIVATIVE; THIOSEMICARBAZIDE; TRIETHYLAMINE; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL ANALYSIS; INFRARED RADIATION; POLYMERIZATION; PROTON NUCLEAR MAGNETIC RESONANCE; SYNTHESIS;

EID: 54349108411     PISSN: 00397911     EISSN: 15322432     Source Type: Journal    
DOI: 10.1080/00397910802241407     Document Type: Article

References (11)

1. Elguero, J. In Comprehensive Heterocyclic Chemistry; A. R. Katritzky, C. W. Rees (Eds.); Pergamon: Oxford, 1984; vol. 5, pp. 167-302.
2. Elguero, J. In Comprehensive Heterocyclic Chemistry II; A. R. Katritzky, C. W. Rees, E. F. Scriven (Eds.); Pergamon: Oxford, 1996; vol. 3, pp. 1-75.
3. Taylor, E. C.; Patel, H.; Kumar, H. Synthesis of pyrazolo 3,4-dpyrimidine analogues of the potent agent N-4-2-2-amino-4 3H-oxo-7H-pyrrolo 2,3-d pyrimidin-5-yl ethylbenzoyl-L- glutamic acid (LY231514). Tetrahedron. 1992, 48, 8089-8100.
4. Karthikeyan, M. S.; Holla, B. S.; Kumari, N. S. Synthesis and antimicrobial studies on novel chloro-fluorine containing hydroxy pyrazolines. Eur. J. Med. Chem. 2007, 42, 30-36.
5. 2-pyrazolines. Farmaco 2000, 55, 256-263.
6. Bansal, E.; Srivatsava, V. K.; Kumar, A. Synthesis and anti-inflammatory activity of 1-acetyl-5-substitute daryl-3-(β-aminonaphthyl)-2-pyrazolines and β-(substitute daminoethyl) amidonaphthalenes. Eur. J. Med. Chem. 2001, 36, 81-92.
7. Manna, F.; Chimenti, F.; Fioravanti, R.; Bolasco, A.; Seecci, D.; Chimenti, P.; Ferlini, C.; Scambia, G. Synthesis of some pyrazole derivatives and preliminary investigation of their affinity binding to P-glycoprotein. Bioorg. Med. Chem. Lett. 2005, 15, 4632-4635.
8. Ahn, J. H.; Kim, H. M.; Jung, S. H.; Kang, S. K.; Kim, K. R.; Rhee, S. D.; Yang, S. D.; Cheon, H. G.; Kim, S. S. Synthesis and DP-IV inhibition of cyano-pyrazoline derivatives as potent anti-diabetic agents. Bioorg. Med. Chem. Lett. 2004, 14, 4461-4465.
9. Rajendera Prasad, Y.; Lakshmana Rao, A.; Prasoona, L.; Murali, K.; Ravi Kumar, P. Synthesis and antidepressant activity of some 1,3,5-triphenyl-2- pyrazolines and 3-(2″-hydroxy naphthalen-1″-yl)-1,5-diphenyl-2- pyrazolines. Bioorg. Med. Chem. Lett. 2005, 15, 5030-5034.
10. Zelenin, K. N.; Tugusheva, A. R.; Yakimovich, S. I.; Alekseev, V. V.; Zerova, E. V. 5-Hydroxy-2-pyrazolines and their 1-substituted analogs. Chem. Heterocyc. Comp. 2002, 38, 668-676.
11. Budakoti, A.; Abid, M.; Azam, A. Synthesis and antiamoebic activity of new 1-N-substituted thiocarbamoyl-3,5-diphenyl-2-pyrazoline derivatives and their Pd(II) complexes. Eur. J. Med. Chem. 2006, 41, 63-70.