The heterozygous disproportionate micromelia (Dmm) mouse: Morphological changes in fetal cartilage precede postnatal dwarfism and compared with lethal homozygotes can explain the mild phenotype

Journal of Histochemistry and Cytochemistry

Volumn 56, Issue 11, 2008, Pages 1003-1011

  Seegmiller, Robert E ^a   Bomsta, Brandon D ^a   Bridgewater, Laura C ^a   Niederhauser, Cindy M ^a   Montaño, Carolina ^a   Sudweeks, Sterling ^a   Eyre, David R ^b   Fernandes, Russell J ^b  

^a BRIGHAM YOUNG UNIVERSITY   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

Author keywords

C propeptide; Chondrodysplasia; Col2a1; Disproportionate micromelia; Extracellular matrix

Indexed keywords

AGGRECAN; MESSENGER RNA; PEPTIDE DERIVATIVE; PROCOLLAGEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARTILAGE CELL; CELL DENSITY; CELL STRUCTURE; COMPARATIVE STUDY; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOPLASM; DWARFISM; ELECTRON MICROSCOPY; ENDOPLASMIC RETICULUM; EXTRACELLULAR MATRIX; FEMALE; FETUS; FIBER; HETEROZYGOTE; HOMOZYGOTE; HYPOTHESIS; MICROMELIA; MORPHOLOGY; MOUSE; MUTATION; NONHUMAN; PERINATAL PERIOD; PHENOTYPE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RIB CARTILAGE; SKELETON; SYNTHESIS; WILD TYPE;

AGGRECANS; ANIMALS; ANIMALS, NEWBORN; CARTILAGE; CHONDROCYTES; COLLAGEN TYPE II; DWARFISM; EXTRACELLULAR MATRIX; HETEROZYGOTE; HOMOZYGOTE; MICE; MICE, MUTANT STRAINS; MUTATION;

ANIMALIA;

EID: 54349105636     PISSN: 00221554     EISSN: None     Source Type: Journal    
DOI: 10.1369/jhc.2008.951673     Document Type: Article

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