Fetal cerebrovascular circulation: A review of prenatal ultrasound assessment

Gynecologic and Obstetric Investigation

Volumn 66, Issue 3, 2008, Pages 184-196

  Degani, S ^a,b  

^a TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

^b BNAI ZION MEDICAL CENTER   (Israel)

Author keywords

Cerebral arterial Doppler waveforms; Cerebral blood flow in normal pregnancy; Complicated pregnancies and deliveries; Doppler flow studies; Fetal cerebrovascular circulation; Prenatal ultrasound assessment; Venous cerebral blood flow

Indexed keywords

GLUCOSE;

ANEMIA; ARTERIOVENOUS MALFORMATION; BLOOD VISCOSITY; BRAIN BLOOD FLOW; BRAIN BLOOD VESSEL; BRAIN CIRCULATION; BRAIN DAMAGE; BRAIN HEMORRHAGE; BREATHING MECHANICS; DOPPLER FLOWMETRY; ECHOENCEPHALOGRAPHY; FETUS BREATHING; FETUS DEATH; FETUS DISTRESS; FETUS HEART RATE; GLUCOSE BLOOD LEVEL; HEMODYNAMIC PARAMETERS; HUMAN; INTERNAL CAROTID ARTERY; INTRACRANIAL PRESSURE; MEDICAL ASSESSMENT; MIDDLE CEREBRAL ARTERY; NONHUMAN; POSTERIOR COMMUNICATING ARTERY; PRENATAL DEVELOPMENT; PRIORITY JOURNAL; REVIEW; TWIN PREGNANCY; ULTRASOUND; VASCULAR RESISTANCE;

AORTA, THORACIC; BLOOD FLOW VELOCITY; BRAIN; CEREBROVASCULAR CIRCULATION; FEMALE; FETUS; HUMANS; INFANT, NEWBORN; PREGNANCY; ULTRASONOGRAPHY, DOPPLER, COLOR; ULTRASONOGRAPHY, PRENATAL;

EID: 54349098996     PISSN: 03787346     EISSN: None     Source Type: Journal    
DOI: 10.1159/000143157     Document Type: Review

References (98)

1. Kiserud T, Acharya G: The fetal circulation. Prenat Diagn 2004;24:1049-1059.
2. Bada HS, Hajjar W, Chua C, et al: Noninvasive diagnosis of neonatal asphyxia and intraventricular hemorrhage by Doppler ultrasound recording of flow velocity in basal cerebral arteries. J Neurosurg 1979;57:769-774.
3. Stoeter P, Voigt K: Prenatal neuroradiology: comparative radiological investigations of the embryonal and fetal brain. Neuroradiology 1978;16:54-57.
4. Neas JF: Cardiovascular System: Development of Vessels and Circulation. Embryology Atlas. Upper Saddle River/NJ, Pearson Education Inc., 2003.
5. Alpers BJ, Berry RG, Paddison RM: Anatomical studies of the circle of Willis in normal brain. Arch Neurol Psychiatry 1959;81:409-418.
6. Milenkovic Z, Vucetic R, Puzic M: Asymmetry and anomalies of the circle of Willis in fetal brain. Microsurgical study and functional remarks. Surg Neurol 1985;24:563-570.
7. Van Overbeeke JJ, Hillen B, Tulleken CA: A comparative study of the circle of Willis in fetal and adult life. The configuration of the posterior bifurcation of the posterior communicating artery. J Anat 1991;176:45-54.
8. Wismer GL: Circle of Willis variant analogous to fetal type primitive trigeminal artery. Neuroradiology 1989;31:366-398.
9. Gailloud P, Albayram S, Fasel JH, Beauchamp NJ, Murphy KJ: Angiographic and embryologic considerations in five cases of middle cerebral artery fenestration. Am J Neuroradiol 2002;23:585-587.
10. Arnold WH, Sperber GH, Machin GA: Anatomy of the circle of Willis in three cases of human fetal synophthalmic holoprosencephaly. Ann Anat 1996;178:553-558.
11. Pilu G, Falco P, Milano V, Perolo A, Bovicelli L: Prenatal diagnosis of microcephaly assisted by vaginal sonography and power Doppler. Ultrasound Obstet Gynecol 1998;11:357-360.
12. Okudera T, Huang YP, Ohta T, Yokota A, Nakamura Y, Maehara F, Utsunomiya H, Uemura K, Fukasawa H: Development of posterior fossa dural sinuses, emissary veins, and jugular bulb: morphological and radiologic study. Am J Neuroradiol 1994;15:1871-1883.
13. Wladimiroff JW, Tonge HM, Stewart PA: Doppler ultrasound assessment of cerebral blood flow in the human fetus. Br J Obstet Gynaecol 1986;93:471-475.
14. Woo JK, Liang ST, Lo RS, et al: Middle cerebral artery Doppler flow velocity waveforms. Obstet Gynecol 1987;70:613-616.
15. Mari G, Moise KJ, Deter RL, et al: Doppler assessment of the pulsatility index in cerebral circulation of the human fetus. Am J Obstet Gynecol 1989;160:698-703.
16. Arbeille PH, Tranquart F, Benson M, et al: Visualization of the fetal circle of Willis and intracerebral arteries by color-coded Doppler. Eur J Obstet Gynecol Reprod Biol 1989;32:195-198.
17. Mirro R, Gonzalez A: Perinatal anterior cerebral artery Doppler flow indexes: methods and preliminary results. Am J Obstet Gynecol 1987;156:1227-1231.
18. Arbeille P, Roncin A, Berson M, et al: Exploration of the fetal cerebral blood flow by duplex Doppler-linear assay system in normal and pathological pregnancies. Ultrasound Med Biol 1987;13:329-337.
19. Meerman RJ, Van Bel F, Van Zuiten PH, et al: Fetal and neonatal cerebral blood velocity in the normal fetus and neonate. Early Hum Dev 1990;24:209-217.
20. Gosling RG, King DH: Ultrasound angiology; in Marcus AW, Adamson L (eds): Arteries and Veins. Edinburgh, Churchill-Livingstone, 1975, pp 61-75.
21. Fong K, Ryan ML, Cohen H, et al: Doppler velocimetry of the fetal middle cerebral and renal arteries: interobserver reliability. J Ultrasound Med 1996;15:317-321.
22. Alcazar JL: Intraobserver variability of pulsatility index measurements in three fetal vessels in the first trimester. J Clin Ultrasound 1997;25:366-371.
23. Arbeille P, Body G, Saliba E, et al: Fetal cerebral circulation assessment by Doppler ultrasound in normal and pathological pregnancies. Eur J Obstet Gynecol Reprod Biol 1988;29:261-273.
24. Arabin B, Mohnhaupt A, Becker R, et al: Comparison of the prognostic value of pulsed Doppler blood flow parameters to predict SGA and fetal distress. Ultrasound Obstet Gynecol 1992;2:272-278.
25. Vyas S, Nicolaides KH, Bower S, et al: Middle cerebral artery flow velocity waveforms in fetal hypoxaemia. Br J Obstet Gynaecol 1990;97:797-803.
26. Laurichesse-Delmass H, Grimaud O, Moscoso G, et al: Color Doppler study of the venous circulation in the fetal brain and hemodynamic study of the cerebral transverse sinus. Ultrasound Obstet Gynecol 1999;13:34-42.
27. Pooh RK, Aono T: Transvaginal power Doppler angiography of the fetal brain. Ultrasound Obstet Gynecol 1996;8:417-421.
28. Hernandez-Andrade E, Jansson T, Figueroa-Diesel H, et al: Evaluation of fetal regional cerebral blood perfusion using power Doppler ultrasound and the estimation of fractional moving blood volume. Ultrasound Obstet Gynecol 2007;29:556-561.
29. Pooh RK, Pooh KH: The assessment of fetal brain morphology and circulation by transvaginal 3D sonography and power Doppler. J Perinat Med 2002;30:48-56.
30. Kurjak A, Predonic M, Kupesic S, et al: Transvaginal color Doppler study of middle cerebral blood flow in early normal and abnormal pregnancy. Ultrasound Obstet Gynecol 1992;2:424-428.
31. Wladimiroff JW, van den Wijngaard JAGW, Degani S, et al: Cerebral and umbilical arterial blood flow velocity waveforms in normal and growth-retarded pregnancies. Obstet Gynecol 1987;69:705-709.
32. Hata K, Hata T, Makihara K, et al: Fetal intracranial arterial hemodynamics assessed by color and pulsed Doppler ultrasound. Int J Gynecol Obstet 1991;35:139-145.
33. Arduini D, Rizzo G: Normal values of pulsatility index from fetal vessels: a cross-sectional study on 1,556 healthy fetuses. J Perinat Med 1990;18:165-172.
34. Mari G, Deter RL: Middle cerebral artery flow velocity waveforms in normal and small-for-gestational-age fetuses. Am J Obstet Gynecol 1992;166:1262-1270.
35. Degani S, Gonen R, Shapiro I, et al: Doppler flow velocity waveform analysis in fetal surveillance of twins: a prospective longitudinal study. J Ultrasound Med 1992;11:537-541.
36. Peeters LLH, Sheldon RE, Jones MD, et al: Blood flow to fetal organs as a function of arterial oxygen content. Am J Obstet Gynecol 1979;135:637-646.
37. Wladimiroff JW, Van Bel F: Fetal and neonatal cerebral blood flow. Semin Perinatol 1987;11:335-346.
38. Mari S, Moise KJ Jr, Deter RL, et al: Fetal heart rate influence on the pulsatility index in the middle cerebral artery. J Clin Ultrasound 1991;19:149-153.
39. Nijhuis JG, Prechtl HFR, Martin CB Jr: Are there behavioral states in the human fetus? Early Hum Dev 1982;6:177-195.
40. Van Eyck J, Wladimiroff JW, van den Wijngaard JA, et al: The blood flow velocity waveform in the fetal internal carotid and umbilical artery: its relation to fetal behavioural states in normal pregnancy at 37-38 weeks. Br J Obstet Gynaecol 1987;94:736-741.
41. Degani S, Paltiely Y, Gonen R, et al: Fetal internal carotid artery pulsed Doppler velocity waveforms and maternal plasma glucose levels. Obstet Gynecol 1991;7:379-381.
42. Pryds O, Greisen G, Friis-Hansen B: Compensatory increase of CBF in preterm infants during hypoglycemia. Acta Peadiatr Scand 1988;77:632-637.
43. Fendel H, Funk A, Jorn J: Cerebral blood flow during labour. Z Geburtsh Perinatol 1990;194:272-274.
44. Yagel S, Anteby E, Levy Y, et al: Fetal middle cerebral artery blood flow during normal active labour and in labour with variable decelerators. Br J Obstet Gynaecol 1992;99:483-485.
45. Mirro R, Gonzalez A: Perinatal anterior cerebral artery Doppler flow indexes: methods and preliminary results. Am J Obstet Gynecol 1987;156:1227-1231.
46. Rizzo G, Capponi A, Arduini D, et al: Uterine and fetal blood flows in pregnancies complicated by preterm labor. Gynecol Obstet Invest 1996;42:163-166.
47. Maesel A, Sladkevicius P, Valentin L, et al: Fetal cerebral blood flow velocity during labor and the early neonatal period. Ultrasound Obstet Gynecol 1995;4:372-376.
48. Ipsiroglu OS, Stockler S, Hausler MCH, et al: Cerebral blood flow velocities in the first minutes of life. Eur J Pediatr 1993;152:269-271.
49. Pooh RK, Aono T: Transvaginal power Doppler angiography of the fetal brain. Ultrasound Obstet Gynecol 1996;8:417-421.
50. Pooh RK, Pooh KH, Nakagawa Y, Maeda K, Fukui R, Aono T: Transvaginal Doppler assessment of fetal intracranial venous flow. Obstet Gynecol 1999;93:697-701.
51. Cheema R, Dubiel M, Breborowicz G, Gudmundsson S: Fetal cerebral venous Doppler velocimetry in normal and high-risk pregnancy. Ultrasound Obstet Gynecol 2004;24:147-153.
52. Laurichesse-Delmas H, Grimaud O, Moscoso G, Ville Y: Color Doppler study of the venous circulation in the fetal brain and hemodynamic study of the cerebral transverse sinus. Ultrasound Obstet Gynecol 1999;13:34-42.
53. Vyas S, Nicolaides KH, Campbell S: Doppler examination of the middle cerebral artery in anemic fetuses. Am J Obstet Gynecol 1990;162:1066-1068.
54. Mari G, Adrignolo A, Abuhamed AZ, et al: Diagnosis of fetal anemia with Doppler ultrasound in the pregnancy complicated by maternal blood group immunization. Ultrasound Obstet Gynecol 1995;5:400-405.
55. Imbar T, Lev-Sagie A, Cohen S, Yanai N, Yagel S: Diagnosis, surveillance, and treatment of the anemic fetus using middle cerebral artery peak systolic velocity measurement. Prenat Diagn 2006;26:45-51.
56. Escribano D, Galindo A, Arbues J, Puente JM, De la Fuente P: Prenatal management of placental chorioangioma: value of the middle cerebral artery peak systolic velocity. Fetal Diagn Ther 2006;21:489-493.
57. Senat MV, Loizeau S, Couderc S, Bernard JP, Ville Y: The value of middle cerebral artery peak systolic velocity in the diagnosis of fetal anemia after intrauterine death of one monochorionic twin. Am J Obstet Gynecol 2003;189:1320-1324.
58. Wong G, Levine D: Increased systolic peak velocity in fetal middle cerebral artery blood flow shown by Doppler sonography in acute fetomaternal hemorrhage. J Ultrasound Med 2005;24:243-246.
59. Cosmi E, Mari G, Delle Chiaie L, Detti L, Akiyama M, Murphy J, Stefos T, Ferguson JE 2nd, Hunter D, Hsu CD, Abuhamad A, Bahado-Singh R: Noninvasive diagnosis by Doppler ultrasonography of fetal anemia resulting from parvovirus infection. Am J Obstet Gynecol 2002;187:1290-1293.
60. 450. Ultrasound Obstet Gynecol 2005;25:331-334.
61. Bartha JL, Abdel-Fattah SA, Hunter A, Denbow M, Kyle P, Soothill PW: Optimal interval between middle cerebral artery velocity measurements when monitoring pregnancies complicated by red cell alloimmunization. Fetal Diagn Ther 2006;21:22-25.
62. Fouron JC, Teyssier G, Maroto E, et al: Diastolic circulatory dynamics in the presence of elevated placental resistance and retrograde diastolic flow in the umbilical artery: a Doppler echographic study in lambs. Am J Obstet Gynecol 1991;164:195-203.
63. Fouron JC, Teyssier G, Shalaby L, Lessard M, et al: Fetal central blood flow alterations in human fetus with umbilical artery reversed diastolic flow. Am J Perinatol 1993;10:197-207.
64. Bilardo CM, Nicolaides KH, Campbell S: Doppler measurements of fetal and uteroplacental circulations: relationship with umbilical venous blood gases measured at cordocentesis. Am J Obstet Gynecol 1990;162:115-120.
65. Akalin Sel T, Nicolaides KH, Peacock J, et al: Doppler dynamics and their complex interrelation with fetal oxygen pressure, carbon dioxide pressure and pH in growth-retarded fetuses. Obstet Gynecol 1994;84:439-444.
66. Degani S, Paltiely Y, Lewinsky R, et al: Fetal blood flow velocity waveforms in pregnancies complicated by intrauterine growth retardation. Isr J Med Sci 1990;26:250-254.
67. Bahado-Singh RO, Kovanci E, Jeffres A, et al: The Doppler cerebroplacental ratios and perinatal outcome in intrauterine growth restriction. Am J Obstet Gynecol 1999;180:750-756.
68. Degani S, Sharf M: Predictive values of Doppler criteria for intrauterine growth retardation in non-umbilical fetal vessels. Isr J Obstet Gynecol 1991;2:138-142.
69. Noordam MJ, Heydanus R, Hop WC, et al.: Doppler color flow imaging of fetal intracerebral arteries and umbilical artery in the small for gestational age fetus. Br J Obstet Gynaecol 1994;101:504-508.
70. Gaziano E, Gaziano C, Brandt D, et al: Doppler velocimetry determined redistribution of fetal blood flow: correlation with growth retardation in diamniotic monochorionic and dizygotic twins. Am J Obstet Gynecol 1998;178:1359-1367.
71. Degani S, Leibovitz Z, Shapiro I, Gonen R, Ohel G: Instability of Doppler cerebral blood flow in monochorionic twins. J Ultrasound Med 2006;25:449-454.
72. Hill A, Volpe JJ: Decrease in pulsatile flow in the anterior cerebral arteries is infantile hydrocephelus. Pediatrics 1982;69:4-7.
73. Degani S, Lewinsky R, Shapiro I, et al: Decrease in pulsatile flow in the internal carotid artery in fetal hydrocephalus. Br J Obstet Gynaecol 1988;95:138-141.
74. Kirkinen P, Muller R, Baumann H, et al: Cerebral blood flow velocity waveforms in hydrocephalic fetuses. J Clin Ultrasound 1988;16:493-498.
75. Mari G, Abuhamad AZ, Keller M, Verpairojkit B, Ment L, Copel JA: Is the fetal brain-sparing effect a risk factor for the development of intraventricular hemorrhage in the preterm infant? Ultrasound Obstet Gynecol 1996;8:329-332.
76. Guerriero S, Ajossa V, Mais A, et al: Color Doppler energy imaging in the diagnosis of fetal intracranial hemorrhage in the second trimester. Ultrasound Obstet Gynecol 1997;10:205-208.
77. De Spirlet M, Goffinet F, Philippe HJ, Bailly M, Couderc S, Nisand I: Prenatal diagnosis of a subdural hematoma associated with reverse flow in the middle cerebral artery: case report and literature review. Ultrasound Obstet Gynecol 2000;16:72-76.
78. Sibony O, Fondacci C, Oury JF, et al: In utero fetal cerebral intraparenchymal hemorrhage associated with an abnormal cerebral Doppler. Fetal Diagn Ther 1993;8:126-128.
79. Rizzo G, Arduini D, Colosimo C Jr, et al: Abnormal fetal cerebral blood flow velocity waveforms as a sign of an aneurysm of the vein of Galen. Fetal Ther 1987;2:75-79.
80. Jeanty P, Kepple D, Roussis P, et al: In utero detection of cardiac failure from an aneurysm of the vein of Galen. Am J Obstet Gynecol 1990;163:50-51.
81. Sepulveda W, Platt CC, Fisk NM: Prenatal diagnosis of arteriovenous malformation using color Doppler ultrasonography: case report and review of the literature. Ultrasound Obstet Gynecol 1995;6:282-286.
82. Goelz R, Mielke G, Gonser M, et al: Prenatal assessment of shunting blood flow in vein of Galen malformation. Ultrasound Obstet Gynecol 1996;8:210-212.
83. Ruano R, Benachi A, Aubry MC, Brunelle F, Dumez Y, Dommergues M: Perinatal threedimensional color power Doppler ultrasonography of vein of Galen aneurysms. J Ultrasound Med 2003;22:1357-1362.
84. Gramellini D, Folli MC, Raboni S, et al: Cerebral umbilical Doppler ratio as a predictor of adverse perinatal outcome. Obstet Gynecol 1992;79:416-420.
85. Arduini D, Rizzo G, Romanini C: Changes of pulsatility index from fetal vessels preceding the onset of late decelerations in growth-retarded fetuses. Obstet Gynecol 1992;79:605-610.
86. Weiner Z, Farmakides G, Schulman H, et al: Central and peripheral hemodynamic changes in fetuses with absent end-diastolic velocity in umbilical artery: correlation with computerized fetal heart rate pattern. Am J Obstet Gynecol 1994;170:509-515.
87. Cynober E, Cabrol D, Uzan M: Fetal cerebral blood flow velocity during labor. Fetal Diagn Ther 1992;7:93-101.
88. Chandran R, Serra-Serra V, Sellers SM, et al: Fetal cerebral Doppler in the recognition of fetal compromise. Br J Obstet Gynaecol 1993;100:139-144.
89. Richardson BS, Carmichael L, Homan L, et al: Fetal cerebral circulatory and metabolic responses during heart rate decelerations with umbilical cord compression. Am J Obstet Gynecol 1996;175:929-936.
90. Gudmundsson S, Tulzer G, Huhta JC, et al: Venous Doppler in the fetus with absent enddiastolic flow in the umbilical artery. Ultrasound Obstet Gynecol 1996;7:262-267.
91. Gembruch U, Baschat AA: Demonstration of fetal coronary blood flow by color-coded and pulsed wave Doppler sonography: a possible indicator of severe compromise and impending demise in intrauterine growth retardation. Ultrasound Obstet Gynecol 1996;7:10-16.
92. Krampl E, Chalubinski K, Schatten C, Husslein P: Does acute hypoxia cause fetal arterial blood flow redistribution? Ultrasound Obstet Gynecol 2001;18:175-177.
93. Sepulveda W, Shennan AH, Peek MJ: Reverse end-diastolic flow in the middle cerebral artery: an agonal pattern in the human fetus. Am J Obstet Gynecol 1996;174:1645-1647.
94. Mari G, Wasserstrum N: Fetal flow velocity waveforms of the fetal circulation preceding fetal death in a case of lupus anticoagulant. Am J Obstet Gynecol 1991;164:776-778.
95. Chandran R, Serra, W, Sellers SM, et al: Fetal middle cerebral artery flow velocity waveforms - a terminal pattern, case report. Br J Obstet Gyneacol 1991;98:937-938.
96. Rizzo G, Capponi A, Pietropolli A, et al: Fetal cardiac and extracardiac flows preceding intrauterine death. Ultrasound Obstet Gynecol 1994;4:139-142.
97. Nijhuis JG, Crevels AJ, van Dongen PW: Fetal brain death: the definition of a fetal heart pattern and its clinical consequences. Obstet Gynecol Surv 1990;45:229-232.
98. Degani S, Lewinsky RM, Shapiro I: Doppler studies in fetal cerebral blood flow. Ultrasound Obstet Gynecol 1994;4:158-165.