Evaluation of a proposed therapeutic protocol in 12 dogs with tentative degenerative myelopathy

Acta Veterinaria Hungarica

Volumn 56, Issue 3, 2008, Pages 293-301

  Polizopoulou, Zoe S ^a   Koutinas, Alexander F ^a   Patsikas, Michael N ^a   Soubasis, Nektarios ^a  

^a ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

Author keywords

Degenerative myelopathy; Dog; Treatment

Indexed keywords

ANIMAL; ANIMAL DISEASE; ANIMAL EXPERIMENT; ANIMAL LAMENESS; ARTICLE; DEGENERATIVE DISEASE; DISEASE COURSE; DOG; DOG DISEASE; FEMALE; GENETIC PREDISPOSITION; HOSPITALIZATION; LUMBAR VERTEBRA; MALE; MYELOGRAPHY; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOLOGY; PHYSIOLOGY; RADIOGRAPHY; TREATMENT FAILURE; VERTEBRA;

ANIMALS; DISEASE PROGRESSION; DOG DISEASES; DOGS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; LAMENESS, ANIMAL; LUMBAR VERTEBRAE; MAGNETIC RESONANCE IMAGING; MALE; MYELOGRAPHY; NEURODEGENERATIVE DISEASES; PHYSICAL CONDITIONING, ANIMAL; SEVERITY OF ILLNESS INDEX; THORACIC VERTEBRAE; TREATMENT FAILURE;

ANIMALIA; CANIS FAMILIARIS;

EID: 54349097827     PISSN: 02366290     EISSN: 15882705     Source Type: Journal    
DOI: 10.1556/AVet.56.2008.3.3     Document Type: Article

References (21)

1. Averill, D. R. Jr. (1973): Degenerative myelopathy in the aging German shepherd dog: clinical and pathologic findings. J. Am. Vet. Med. Assoc. 162, 1045-1051.
2. Bagley, R. (2005): Paraparesis. In: Bagley, R. (ed.) Fundamentals of Veterinary Clinical Neurology. Blackwell, Ames. pp. 152-153.
3. Barclay, K. B. and Haines, D. M. (1994): Immunohistochemical evidence for immunoglobulin and complement deposition in spinal cord lesions in degenerative myelopathy in German shepherd dogs. Can. J. Vet. Res. 58, 20-24.
4. Bichsel, P. and Vandevelde, M. (1983): Degenerative myelopathy in a family of Siberian Husky dogs. J. Am. Vet. Med. Assoc. 183, 998-1000.
5. Boothe, D. M. (2001): Drugs acting on coagulation and clotting. In: Boothe, D. M. (ed.) Small Animal Clinical Pharmacology and Therapeutics. W. B. Saunders, Philadelphia. pp. 107-124.
6. Braund, K. G. (2003): Degenerative disorders of the central nervous system. In: Vite, C. H. (ed.) Braund's Clinical Neurology in Small Animals: Localization, Diagnosis and Treatment. International Veterinary Information Service (www.ivis.org), Ithaca, Document No. A3220.0303.
7. Braund, K. G. and Vandevelde, M. (1978): German shepherd dog myelopathy - a morphologic and morphometric study. Am. J. Vet. Res. 39, 1309-1315.
8. Clemmons, R. M. (1989): Degenerative myelopathy. In: Kirk, R. (ed.) Current Veterinary Therapy X. Small Animal Practice. W. B. Saunders, Philadelphia. pp. 830-833.
9. Clemmons, R. M. (1992): Degenerative myelopathy. Vet. Clin. North Am. Small Anim. Pract. 22, 965-971.
10. Coates, J. R. (2004): Degenerative myelopathy. In: Platt, S. R. and Olby, N. J. (eds) Manual of Canine and Feline Neurology. 3rd edition. BSAVA Publications. pp. 242-243.
11. Griffiths, I. R. and Duncan, I. D. (1975): Chronic radiculomyelopathy in the dog. J. Small Anim. Pract. 16, 461-471.
12. Johnston, P. E., Barrie, J. A., McCulloch, M. C., Anderson, T. J. and Griffiths, I. R. (2000): Central nervous system pathology in 25 dogs with chronic degenerative radiculomyelopathy. Vet. Rec. 146, 629-633.
13. Jones, J. C. and Inzana, K. D. (2000): Subclinical CT abnormalities in the lumbosacral spine of older large-breed dogs. Vet. Radiol. Ultrasound 41, 19-26.
14. Jones, J. C., Inzana, K. D., Rossmeisl, J. H., Bergman, R. L., Wells, T. and Butler, K. (2005): CT myelography of the thoraco-lumbar spine in 8 dogs with degenerative myelopathy. J. Vet. Sci. 6, 341-348.
15. Kathman, I., Cizinauskas, S., Doherr, M. G., Steffen, F. and Jaggy, A. (2006): Daily controlled physiotherapy increases survival time in dogs with suspected degenerative myelopathy. J. Vet. Int. Med. 20, 927-932.
16. Longhofer, S. L., Duncan, I. D. and Messing, A. (1990): A degenerative myelopathy in young German shepherd dogs. J. Small Anim. Pract. 31, 199-203.
17. Olby, N. J. (2004): Tetraparesis. In: Platt, S. R. and Olby, N. J. (eds) Manual of Canine and Feline Neurology. 3rd edition. BSAVA Publications. pp. 218-220.
18. Polizopoulou, Z. S., Koutinas, A. F., Patsikas, M. N., Soubasis, N. and Danourdis, T. (2006): Long-term assessment of a currently recommended therapeutic protocol in 12 dogs with tentative degenerative myelopathy: a retrospective study. J. Vet. Int. Med. 20, 1282.
19. Summers, B. A., Cummings, J. A. and DeLahunta, A. (1995): Degenerative myelopathy of old animals. In: Summers, B. A., Cummings, J. A. and DeLahunta, A. (eds) Veterinary Neuropathology. Mosby, St. Louis. pp. 319-321.
20. Waxman, F. J., Clemmons, R. M., Johnson, G., Evermann, J. F., Johnson, M. I., Roberts, C. and Hinrichs, D. J. (1980a): Progressive myelopathy in older German shepherd dogs. I. Depressed response to thymus-dependent mitogens. J. Immunol. 124, 1209-1215.
21. Waxman, F. J., Clemmons, R. M. and Hinrichs, D. J. (1980b): Progressive myelopathy in older German shepherd dogs. II. Presence of circulating suppressor cells. J. Immunol. 124, 1216-1222.