Heparanase expression, degradation of basement membrane and low degree of infiltration by immunocytes correlate with invasion and progression of human gastric cancer

World Journal of Gastroenterology

Volumn 14, Issue 24, 2008, Pages 3812-3818

  Xie, Zun Jiang ^a   Liu, Ying ^a   Jia, Li Min ^a   He, Ye Chun ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

Basement membrane; Gastric cancer; Heparanase; Tumor infiltrating dendritic cell; Tumor infiltrating lymphocyte

Indexed keywords

HEPARANASE; MESSENGER RNA; PROTEIN S 100;

ARTICLE; BASEMENT MEMBRANE; BASEMENT MEMBRANE DEGRADATION; CANCER GROWTH; CANCER INVASION; CANCER STAGING; CANCER TISSUE; CELL DENSITY; CELLULAR DISTRIBUTION; CLINICAL ARTICLE; DEGRADATION; DENDRITIC CELL; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; LYMPHOCYTIC INFILTRATION; METASTASIS; STOMACH CANCER; TRANSMISSION ELECTRON MICROSCOPY; TUMOR ASSOCIATED LEUKOCYTE;

EID: 54349097296     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.14.3812     Document Type: Article

References (37)

1. Poste G, Fidler IJ. The pathogenesis of cancer metastasis. Nature 1980; 263: 139-146
2. Ajani JA, Mansfield PF, Ota DM. Potentially resectable gastric carcinoma: current approaches to staging and preoperative therapy. World J Surg 1995; 19: 216-220
3. Grigioni WF, D'Errico A, Fortunato C, Fiorentino M, Mancini AM, Stetler-Stevenson WG, Sobel ME, Liotta LA, Onisto M, Garbisa S. Prognosis of gastric carcinoma revealed by interactions between tumor cells and basement membrane. Mod Pathol 1994; 7: 220-225
4. Nakajima M, Irimura T, Nicolson GL. Heparanases and tumor metastasis. J Cell Biochem 1988; 36: 157-167
5. Bernfield M, Gotte M, Park PW, Reizes O, Fitzgerald ML, Lincecum J, Zako M. Functions of cell surface heparan sulfate proteoglycans. Annu Rev Biochem 1999; 68: 729-777
6. Tang W, Nakamura Y, Tsujimoto M, Sato M, Wang X, Kurozumi K, Nakaharra M, Nakao K, Nakamura M, Mori I, Kakudo K. Heparanase: a key enzyme in invasion and metastasis of gastric carcinoma. Mod Pathol 2002; 15: 593-598
7. Ohkawa T, Naomoto Y, Takaoka M, Nobuhisa T, Noma K, Motoki T, Murata T, Uetsuka H, Kobayashi M, Shirakawa Y, Yamatsuji T, Matsubara N, Matsuoka J, Haisa M, Gunduz M, Tsujigiwa H, Nagatsuka H, Hosokawa M, Nakajima M, Tanaka N. Localization of heparanase in esophageal cancer cells: respective roles in prognosis and differentiation. Lab Invest 2004; 84: 1289-1304
8. Nobuhisa T, Naomoto Y, Ohkawa T, Takaoka M, Ono R, Murata T, Gunduz M, Shirakawa Y, Yamatsuji T, Haisa M, Matsuoka J, Tsujigiwa H, Nagatsuka H, Nakajima M, Tanaka N. Heparanase expression correlates with malignant potential in human colon cancer. J Cancer Res Clin Oncol 2005; 131: 229-237
9. Lipponen PK. The prognostic value of basement membrane morphology, tumour histology and morphometry in superficial bladder cancer. J Cancer Res Clin Oncol 1993; 119: 295-300
10. Xie ZJ, Jia LM, He YC, Gao JT. Morphological observation of tumor infiltrating immunocytes in human rectal cancer. World J Gastroenterol 2006; 12: 1757-1760
11. Zeid NA, Muller HK. S100 positive dendritic cells in human lung tumors associated with cell differentiation and enhanced survival. Pathology 1993; 25: 338-343
12. Tsujitani S, Kakeji Y, Watanabe A, Kohnoe S, Maehara Y, Sugimachi K. Infiltration of dendritic cells in relation to tumor invasion and lymph node metastasis in human gastric cancer. Cancer 1990; 66: 2012-2016
13. Lespagnard L, Gancberg D, Rouas G, Leclercq G, de Saint-Aubain Somerhausen N, Di Leo A, Piccart M, Verhest A, Larsimont D. Tumor-infiltrating dendritic cells in adenocarcinomas of the breast: a study of 143 neoplasms with a correlation to usual prognostic factors and to clinical outcome. Int J Cancer 1999; 84: 309-314
14. Iwamoto M, Shinohara H, Miyamoto A, Okuzawa M, Mabuchi H, Nohara T, Gon G, Toyoda M, Tanigawa N. Prognostic value of tumor-infiltrating dendritic cells expressing CD83 in human breast carcinomas. Int J Cancer 2003; 104: 92-97
15. Sandel MH, Dadabayev AR, Menon AG, Morreau H, Melief CJ, Offringa R, van der Burg SH, Janssen-van Rhijn CM, Ensink NG, Tollenaar RA, van de Velde CJ, Kuppen PJ. Prognostic value of tumor-infiltrating dendritic cells in colorectal cancer: role of maturation status and intratumoral localization. Clin Cancer Res 2005; 11: 2576-2582
16. Tsujihashi H, Uejima S, Akiyama T, Kurita T. Immunohistochemical detection of tissue-infiltrating lymphocytes in bladder tumors. Urol Int 1989; 44: 5-9
17. Eerola AK, Soini Y, Paakko P. A high number of tumor-infiltrating lymphocytes are associated with a small tumor size, low tumor stage, and a favorable prognosis in operated small cell lung carcinoma. Clin Cancer Res 2000; 6: 1875-1881
18. Tormanen-Napankangas U, Soini Y, Paakko P. High number of tumour-infiltrating lymphocytes is associated with apoptosis in non-small cell lung carcinoma. APMIS 2001; 109: 525-532
19. Sobin LH, Fleming ID. TNM Classification of Malignant Tumors, fifth edition (1997). Union Internationale Contre le Cancer and the American Joint Committee on Cancer. Cancer 1997; 80: 1803-1804
20. Koliopanos A, Friess H, Kleeff J, Shi X, Liao Q, Pecker I, Vlodavsky I, Zimmermann A, Buchler MW. Heparanase expression in primary and metastatic pancreatic cancer. Cancer Res 2001; 61: 4655-4659
21. Beckhove P, Helmke BM, Ziouta Y, Bucur M, Dorner W, Mogler C, Dyckhoff G, Herold-Mende C. Heparanase expression at the invasion front of human head and neck cancers and correlation with poor prognosis. Clin Cancer Res 2005; 11: 2899-2906
22. Takaoka M, Naomoto Y, Ohkawa T, Uetsuka H, Shirakawa Y, Uno F, Fujiwara T, Gunduz M, Nagatsuka H, Nakajima M, Tanaka N, Haisa M. Heparanase expression correlates with invasion and poor prognosis in gastric cancers. Lab Invest 2003; 83: 613-622
23. Kurokawa H, Katsube K, Podyma KA, Ikuta M, Iseki H, Nakajima M, Akashi T, Omura K, Takagi M, Yanagishita M. Heparanase and tumor invasion patterns in human oral squamous cell carcinoma xenografts. Cancer Sci 2003; 94: 277-285
24. Chauhan SS, Goldstein M, Gottesman MM. Expression of cathepsin L in human tumors. Cancer Res 1991; 51: 1478-1481
25. Perrot I, Blanchard D, Freymond N, Isaac S, Guibert B, Pacheco Y, Lebecque S. Dendritic cells infiltrating human non-small cell lung cancer are blocked at immature stage. J Immunol 2007; 178: 2763-2769
26. Matsuda H, Mori M, Tsujitani S, Ohno S, Kuwano H, Sugimachi K. Immunohistochemical evaluation of squamous cell carcinoma antigen and S-100 protein-positive cells in human malignant esophageal tissues. Cancer 1990; 65: 2261-2265
27. Tsujitani S, Kakeji Y, Watanabe A, Kohnoe S, Maehara Y, Sugimaghi K. Infiltration of S-100 protein positive dendritic cells and peritoneal recurrence in advanced gastric cancer. Int Surg 1992; 77: 238-241
28. Ambe K, Mori M, Enjoji M. S-100 protein-positive dendritic cells in colorectal adenocarcinomas. Distribution and relation to the clinical prognosis. Cancer 1989; 63: 496-503
29. Inoue K, Furihata M, Ohtsuki Y, Fujita Y. Distribution of S-100 protein-positive dendritic cells and expression of HLADR antigen in transitional cell carcinoma of the urinary bladder in relation to tumour progression and prognosis. Virchows Arch A Pathol Anal Histopathol 1993; 422: 351-355
30. Lipponen PK, Eskelinen MJ, Jauhiainen K, Harju E, Terho R. Tumour infiltrating lymphocytes as an independent prognostic factor in transitional cell bladder cancer. Eur J Cancer 1992; 29A: 69-75
31. Ropponen KM, Eskelinen MJ, Upponen PK, Alhava E, Kosma. VM. Prognostic value of tumour-infiltrating lymphocytes (TILs) in colorectal cancer. J Pathol 1997; 182: 318-324
32. Aaltomaa S, Lipponen P, Eskelinen M, Kosma VM, Marin S, Alhava E, Syrjanen K. Lymphocyte infiltrates as a prognostic variable in female breast cancer. Eur J Cancer 1992; 28A: 859-864
33. Suzuki A, Masuda A, Nagata H, Kameoka S, Kikawada Y, Yamakawa M, Kasajima T. Mature dendritic cells make clusters with T cells in the invasive margin pf colorectal carcinoma. J Pathol 2002; 196: 37-43
34. Schuler G, Steinman RM. Dendritic cells as adjuvants for immune-mediated resistance to tumors. J Exp Med 1997; 186: 1183-1187
35. Bell D, Chomarat P, Broyles D, Netto G, Harb GM, Lebecque S, Valladeau J, Davoust J, Palucka KA, Banchereau J. In breast carcinoma tissue, immature dendritic cells reside within the tumor, whereas mature dendritic cells are located in peritumoral areas. J Exp Med 1999; 190: 1417-1426
36. Flechner ER, Freudenthal PS, Kaplan G, Steinman RM. Antigen-specific T lymphocytes efficiently cluster with dendritic cells in the human primary mixed-leukocyte reaction. Cell Immunol 1988; 111: 183-195
37. Austyn JM, Weinstein DE, Steinman RM. Clustering with dendritic cells precedes and is essential for T-cell proliferation in a mitogenesis model. Immunology 1988; 63: 691-696