Fetal origins of perinatal morbidity and/or adult disease

Seminars in Reproductive Medicine

Volumn 26, Issue 5, 2008, Pages 436-446

  Rinaudo, Paolo F ^a   Lamb, Julie ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

ART; Barker hypothesis; Cardiovascular disease; Hypertension; Intrauterine stress; Low birth weight

Indexed keywords

ADULT DISEASE; CARDIOVASCULAR DISEASE; DIABETES MELLITUS; EMBRYO CULTURE; EMBRYO DEVELOPMENT; FETUS DEVELOPMENT; GENE EXPRESSION; HUMAN; HYPERTENSION; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; INFERTILITY THERAPY; KIDNEY DISEASE; METHYLATION; NONHUMAN; PERINATAL MORBIDITY; PRENATAL STRESS; REVIEW; STROKE;

ADULT; CARDIOVASCULAR DISEASES; DISEASE; ENDOCRINE SYSTEM DISEASES; FEMALE; FETAL DISEASES; HUMANS; HYPERTENSION; INFANT, NEWBORN; INFANT, NEWBORN, DISEASES; MODELS, BIOLOGICAL; MORBIDITY; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; STRESS, PHYSIOLOGICAL; STROKE;

EID: 54349095825     PISSN: 15268004     EISSN: 15264564     Source Type: Journal    
DOI: 10.1055/s-0028-1087109     Document Type: Review

References (86)

1. Barker DJ. Mothers, Babies and Health in Later Life. Glasgow, Scotland: Churchill Livingstone; 1998
2. Barker DJ, Winter PD, Osmond C, Margetts B, Simmonds SJ. Weight in infancy and death from ischaemic heart disease. Lancet 1989;2:577-580
3. Godfrey KM, Barker DJ. Fetal programming and adult health. Public Health Nutr 2001;4:611-624
4. Gluckman PD, Hanson MA. Developmental plasticity and human disease: research directions. J Intern Med 2007;261:461-471
5. O'Brien PMSWT, Barker DJP. Foetal Programming: Influences on Development and Disease in Later Life. London, United Kingdom: RCOG Press; 1999
6. Morley R. Fetal origins of adult disease. Semin Fetal Neonatal Med 2006;11:73-78
7. Lawlor DA, Ronalds G, Clark H, Smith GD, Leon DA. Birth weight is inversely associated with incident coronary heart disease and stroke among individuals born in the 1950s: findings from the Aberdeen Children of the 1950s prospective cohort study. Circulation 2005;112:1414-1418
8. Leon DA, Lithell HO, Vagero D, et al. Reduced fetal growth rate and increased risk of death from ischaemic heart disease: cohort study of 15 000 Swedish men and women born 1915-29. BMJ 1998;317:241-245
9. Rich-Edwards JW, Kleinman K, Michels KB, et al. Longitudinal study of birth weight and adult body mass index in predicting risk of coronary heart disease and stroke in women. BMJ 2005;330:1115-1118
10. Barker DJ, Eriksson JG, Forsen T, Osmond C. Fetal origins of adult disease: strength of effects and biological basis. Int J Epidemiol 2002;31:1235-1239
11. Hypponen E, Leon DA, Kenward MG, Lithell H. Prenatal growth and risk of occlusive and haemorrhagic stroke in Swedish men and women born 1915-29: historical cohort study. BMJ 2001;323:1033-1034
12. Law CM, Shiell AW. Is blood pressure inversely related to birth weight? The strength of evidence from a systematic review of the literature. J Hypertens 1996;14:935-941
13. Huxley R, Neil A, Collins R. Unravelling the fetal origins hypothesis: is there really an inverse association between birthweight and subsequent blood pressure? Lancet 2002;360:659-665
14. Cruickshank JK, Beith C, Koudsi A. Unravelling the fetal origins hypothesis. Lancet 2002;360:2073-2074; author reply 2074-2075
15. Holemans K, Caluwaerts S, Van Assche FA. Unravelling the fetal origins hypothesis. Lancet 2002;360:2073; author reply 2074-2075
16. Eriksson JG, Forsen T. Unravelling the fetal origins hypothesis. Lancet 2002;360:2072 author reply 2074-2075
17. Hennessy E. Unravelling the fetal origins hypothesis. Lancet 2002;360:2072-2073; author reply 2074-2075
18. Hemachandra AH, Klebanoff MA, Duggan AK, Hardy JB, Furth SL. The association between intrauterine growth restriction in the full-term infant and high blood pressure at age 7 years: results from the Collaborative Perinatal Project. Int J Epidemiol 2006;35:871-877
19. Menezes AM, Hallal PC, Horta BL, et al. Size at birth and blood pressure in early adolescence: a prospective birth cohort study. Am J Epidemiol 2007;165:611-616
20. Gamborg M, Byberg L, Rasmussen F, et al. Birth weight and systolic blood pressure in adolescence and adulthood: metaregression analysis of sex- and age-specific results from 20 Nordic studies. Am J Epidemiol 2007;166:634-645
21. Shankaran S, Das A, Bauer CR, et al. Fetal origin of childhood disease: intrauterine growth restriction in term infants and risk for hypertension at 6 years of age. Arch Pediatr Adolesc Med 2006;160:977-981
22. Davies AA, Smith GD, May MT, Ben-Shlomo Y. Association between birth weight and blood pressure is robust, amplifies with age, and may be underestimated. Hypertension 2006;48:431-436
23. Stein AD, Zybert PA, van der Pal-de Bruin K, Lumey LH. Exposure to famine during gestation, size at birth, and blood pressure at age 59 y: evidence from the Dutch Famine. Eur J Epidemiol 2006;21:759-765
24. Mzayek F, Hassig S, Sherwin R, et al. The association of birth weight with developmental trends in blood pressure from childhood through mid-adulthood: the Bogalusa Heart study. Am J Epidemiol 2007;166:413-420
25. Hardy R, Sovio U, King VJ, et al. Birthweight and blood pressure in five European birth cohort studies: an investigation of confounding factors. Eur J Public Health 2006;16:21-30
26. Gortner L. Intrauterine growth restriction and risk for arterial hypertension: a causal relationship? J Perinat Med 2007;35:361-365
27. Halvorsen CP, Andolf E, Hu J, Pilo C, Winbladh B, Norman M. Discordant twin growth in utero and differences in blood pressure and endothelial function at 8 years of age. J Intern Med 2006;259:155-163
28. Vehaskari VM, Woods LL. Prenatal programming of hypertension: lessons from experimental models. J Am Soc Nephrol 2005;16:2545-2556
29. Martyn CN, Greenwald SE. A hypothesis about a mechanism for the programming of blood pressure and vascular disease in early life. Clin Exp Pharmacol Physiol 2001;28:948-951
30. Barker DJHC, Fall CH, Osmond C, Phipps K, Clark P. Type 2 (non-insulin-dependent) diabetes mellitus, hypertension and hyperlipidaemia (syndrome X): relation to reduced fetal growth. Diabetologica 1993;36:62-67
31. Law CM, Gordon GS, Shiell AW, Barker DJ, Hales CN. Thinness at birth and glucose tolerance in seven-year-old children. Diabet Med 1995;12:24-29
32. Rich-Edwards JW, Colditz GA, Stampfer MJ, et al. Birthweight and the risk for type 2 diabetes mellitus in adult women. Ann Intern Med 1999;130:278-284
33. Hales CN, Barker DJ, Clark PM, et al. Fetal and infant growth and impaired glucose tolerance at age 64. BMJ 1991;303:1019-1022
34. Lithell HO, McKeigue PM, Berglund L, Mohsen R, Lithell UB, Leon DA. Relation of size at birth to non-insulin dependent diabetes and insulin concentrations in men aged 50-60 years. BMJ 1996;312:406-410
35. Forsen T, Eriksson J, Tuomilehto J, Reunanen A, Osmond C, Barker D. The fetal and childhood growth of persons who develop type 2 diabetes. Ann Intern Med 2000;133:176-182
36. Newsome CA, Shiell AW, Fall CH, Phillips DI, Shier R, Law CM. Is birth weight related to later glucose and insulin metabolism? A systematic review. Diabet Med 2003;20:339-348
37. Mackenzie HS, Brenner BM. Fewer nephrons at birth: a missing link in the etiology of essential hypertension? Am J Kidney Dis 1995;26:91-98
38. Brenner BM, Lawler EV, Mackenzie HS. The hyperfiltration theory: a paradigm shift in nephrology. Kidney Int 1996;49:1774-1777
39. Brenner BM, Chertow GM. Congenital oligonephropathy: an inborn cause of adult hypertension and progressive renal injury? Curr Opin Nephrol Hypertens 1993;2:691-695
40. Brenner BM, Chertow GM. Congenital oligonephropathy and the etiology of adult hypertension and progressive renal injury. Am J Kidney Dis 1994;23:171-175
41. Mackenzie HS, Lawler EV, Brenner BM. Congenital oligonephropathy: the fetal flaw in essential hypertension? Kidney Int Suppl 1996;55:S30-S34
42. Edwards CR, Benediktsson R, Lindsay RS, Seckl JR. Dysfunction of placental glucocorticoid barrier: link between fetal environment and adult hypertension? Lancet 1993;341:355-357
43. Jaddoe VW, Witteman JC. Hypotheses on the fetal origins of adult diseases: contributions of epidemiological studies. Eur J Epidemiol 2006;21:91-102
44. Weaver IC, Cervoni N, Champagne FA, et al. Epigenetic programming by maternal behavior. Nat Neurosci 2004;7:847-854
45. Francis DD, Caldji C, Champagne F, Plotsky PM, Meaney MJ. The role of corticotropin-releasing factor-norepinephrine systems in mediating the effects of early experience on the development of behavioral and endocrine responses to stress. Biol Psychiatry 1999;46:1153-1166
46. Francis DD, Diorio J, Plotsky PM, Meaney MJ. Environmental enrichment reverses the effects of maternal separation on stress reactivity. J Neurosci 2002;22:7840-7843
47. Meaney MJ, Bhatnagar S, Larocque S, et al. Individual differences in the hypothalamic-pituitary-adrenal stress response and the hypothalamic CRF system. Ann N Y Acad Sci 1993;697:70-85
48. Adamson GD, de Mouzon J, Lancaster P, Nygren KG, Sullivan E, Zegers-Hochschild F. World collaborative report on in vitro fertilization, 2000. Fertil Steril 2006;85:1586-1622
49. Kalra SK, Molinaro TA. The association of in vitro fertilization and perinatal morbidity. Semin Reprod Med 2008;26:423-435
50. Hansen M, Kurinczuk JJ, Bower C, Webb S. The risk of major birth defects after intracytoplasmic sperm injection and in vitro fertilization. N Engl J Med 2002;346:725-730
51. Schieve LA, Meikle SF, Ferre C, Peterson HB, Jeng G, Wilcox LS. Low and very low birth weight in infants conceived with use of assisted reproductive technology. N Engl J Med 2002;346:731-737
52. Stromberg B, Dahlquist G, Ericson A, Finnstrom O, Koster M, Stjernqvist K. Neurological sequelae in children born after in-vitro fertilisation: a population-based study. Lancet 2002;359:461-465
53. Kovalevsky G, Rinaudo P, Coutifaris C. Do assisted reproductive technologies cause adverse fetal outcomes? Fertil Steril 2003;79:1270-1272
54. Anthony S, Buitendijk SE, Dorrepaal CA, Lindner K, Braat DD, den Ouden AL. Congenital malformations in 4224 children conceived after IVF. Hum Reprod 2002;17:2089-2095
55. Wennerholm UB, Bergh C, Hagberg H, Sultan B, Wennergren M. Gestational age in pregnancies after in vitro fertilization: comparison between ultrasound measurement and actual age. Ultrasound Obstet Gynecol 1998;12:170-174
56. Bartolomei MS, Tilghman SM. Genomic imprinting in mammals. Annu Rev Genet 1997;31:493-525
57. Sutcliffe AG, Peters CJ, Bowdin S, et al. Assisted reproductive therapies and imprinting disorders - a preliminary British survey. Hum Reprod 2006;21:1009-1011
58. Maher ER, Brueton LA, Bowdin SC, et al. Beckwith-Wiedemann syndrome and assisted reproduction technology (ART). J Med Genet 2003;40:62-64
59. DeBaun MR, Niemitz EL, Feinberg AP. Association of in vitro fertilization with Beckwith-Wiedemann syndrome and epigenetic alterations of LIT1 and H19. Am J Hum Genet 2003;72:156-160
60. Chang AS, Moley KH, Wangler M, Feinberg AP, Debaun MR. Association between Beckwith-Wiedemann syndrome and assisted reproductive technology: a case series of 19 patients. Fertil Steril 2005;83:349-354
61. Gicquel C, Gaston V, Mandelbaum J, Siffroi JP, Flahault A, Le Bouc Y. In vitro fertilization may increase the risk of Beckwith-Wiedemann syndrome related to the abnormal imprinting of the KCN1OT gene. Am J Hum Genet 2003;72:1338-1341
62. Ludwig M, Katalinic A, Gross S, Sutcliffe A, Varon R, Horsthemke B. Increased prevalence of imprinting defects in patients with Angelman syndrome born to subfertile couples. J Med Genet 2005;42:289-291
63. Cox GF, Burger J, Lip V, et al. Intracytoplasmic sperm injection may increase the risk of imprinting defects. Am J Hum Genet 2002;71:162-164
64. Moll AIS, Cruysberg J, Schouten-van Meeteren A, Boers M, van Leeuwen F. Incidence of retinoblastoma in children born after in-vitro fertilization. Lancet 2003;361:309-310
65. Langley-Evans SC Sr, Welham SJM, Nwagwu MO, Gardner DS, Jackson AA. Intrauterine programming of hypertension: The role of renin-angiotensin system. Biochem Soc Trans 1999;27:88-93
66. Kwong WYWA, Roberts P, Willis AC, Fleming TP. Maternal undernutrition during the preimplantation period of rat development causes blastocyst abnormalities and programming of postnatal hypertension. Development 2000;127:4195-4202
67. Walker SK, Hartwich KM, Robinson JS. Long-term effects on offspring of exposure of oocytes and embryos to chemical and physical agents. Hum Reprod Update 2000;6:564-577
68. Ogonuki NIK, Yamamoto Y, Noguchi Y, et al. Early death of mice cloned from somatic cells. Nat Genet 2002;30:253-254
69. Edwards JSF, McCracken M, Amstel S, Hopkins F, Welborn M, Davies C. Cloning adult farm animals: a review of the possibilities and problems associated with somatic cell nuclear transfer. Am J Reprod Immunol 2003;50:113-123
70. Kruip TA. In vitro produced and cloned embryos: effect on pregnancy, parturition and offspring. Theriogenology 1997;47:43-52
71. Willadsen SM. The developmental capacity of blastomeres. J Embryol Exp Morphol 1981;57:165-172
72. Ecker DJ, Stein P, Xu Z, et al. Long-term effects of culture of preimplantation mouse embryos on behavior. Proc Natl Acad Sci U S A 2004;101:1595-1600
73. Fernandez-Gonzalez R, Moreira P, Bilbao A, et al. Long-term effect of in vitro culture of mouse embryos with serum on mRNA expression of imprinting genes, development, and behavior. Proc Natl Acad Sci U S A 2004;101:5880-5885
74. Dugan KJ, Shalika S, Smith RD, Padilla SL. Comparison of synthetic serum substitute and fetal cord serum as media supplements for in vitro fertilization: a prospective, randomized study. Fertil Steril 1997;67:166-168
75. Ertzeid G, Storeng R. The impact of ovarian stimulation on implantation and fetal development in mice. Hum Reprod 2001;16:221-225
76. Rinaudo PF, Giritharan G, Talbi S, Dobson AT, Schultz RM. Effects of oxygen tension on gene expression in preimplantation mouse embryos. Fertil Steril 2006;86(Suppl 4):1252-1265
77. Lonergan P, Rizos D, Gutierrez-Adan A, Fair T, Boland MP. Effect of culture environment on embryo quality and gene expression - experience from animal studies. Reprod Biomed Online 2003;7:657-663
78. Gutierrez-Adan A, Rizos D, Fair T, et al. Effect of speed of development on mRNA expression pattern in early bovine embryos cultured in vivo or in vitro. Mol Reprod Dev 2004;68:441-448
79. Rinaudo P, Schultz RM. Effects of embryo culture on global pattern of gene expression in preimplantation mouse embryos. Reproduction 2004;128:301-311
80. Giritharan G, Talbi S, Dobson AT, Rosen M, Di Sebastiano F, Rinaudo PF. Embryo culture results in altered expression of specific imprinted genes in mouse blastocysts. Presented at: European Society of Human Reproduction and Embryology; 2006; Prague, Czech Republic
81. Giritharan G, Talbi S, Donjacour A, Di Sebastiano F, Dobson AT, Rinaudo PF. Effect of in vitro fertilization on gene expression and development of mouse preimplantation embryos. Reproduction 2007;134:63-72
82. Monk M, Boubelik M, Lehnert S. Temporal and regional changes in DNA methylation in the embryonic, extraembryonic and germ cell lineages during mouse embryo development. Development 1987;99:371-382
83. Kafri T, Ariel M, Brandeis M, et al. Developmental pattern of gene-specific DNA methylation in the mouse embryo and germ line. Genes Dev 1992;6:705-714
84. Doherty AS, Mann MR, Tremblay KD, Bartolomei MS, Schultz RM. Differential effects of culture on imprinted H19 expression in the preimplantation mouse embryo. Biol Reprod 2000;62:1526-1535
85. Li T, Vu TH, Ulaner GA, et al. IVF results in de novo DNA methylation and histone methylation at an Igf2-H19 imprinting epigenetic switch. Mol Hum Reprod 2005;11:631-640
86. Shi W, Haaf T. Aberrant methylation patterns at the two-cell stage as an indicator of early developmental failure. Mol Reprod Dev 2002;63:329-334