Dissecting HDAC3-mediated tumor progression

Cancer Biology and Therapy

Volumn 7, Issue 10, 2008, Pages 1581-1583

  Mariadason, John M ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

Cancer; Colon; HDAC3; HDACi; Histone; VDR; Wnt

Indexed keywords

BETA CATENIN; CELL PROTEIN; CYTOPLASM PROTEIN; DNA; HISTONE; HISTONE ACETYLTRANSFERASE; HISTONE DEACETYLASE 1; HISTONE DEACETYLASE 2; HISTONE DEACETYLASE 3; HISTONE DEACETYLASE 4; HISTONE DEACETYLASE 5; HISTONE DEACETYLASE 6; HISTONE DEACETYLASE 7; HISTONE DEACETYLASE 8; HISTONE DEACETYLASE INHIBITOR; INTERFERON; LYSINE; PROTEIN; SHORT HAIRPIN RNA; T CELL FACTOR PROTEIN; TRANSFORMING GROWTH FACTOR BETA; VITAMIN D; VORINOSTAT; WNT1 PROTEIN;

APOPTOSIS; BINDING AFFINITY; BIOLOGICAL ACTIVITY; BREAST CANCER; CANCER CELL; CANCER CELL CULTURE; CANCER CHEMOTHERAPY; CANCER STAGING; CARCINOGENESIS; CELL CYCLE PROGRESSION; CELL DIFFERENTIATION; CELL PROLIFERATION; COLON CANCER; COLORECTAL CANCER; COMPLEX FORMATION; CONTROLLED STUDY; CUTANEOUS T CELL LYMPHOMA; DEACETYLATION; DROSOPHILA; ENZYME MECHANISM; FIBROBLAST; GENE EXPRESSION; HEMATOLOGIC MALIGNANCY; HUMAN; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; NOTE; PROMOTER REGION; PROSTATE CANCER; PROTEIN EXPRESSION; SOLID TUMOR; SURVIVAL; TUMOR GROWTH; VITAMIN SUPPLEMENTATION;

EID: 54349091299     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.7.10.6863     Document Type: Note

References (15)

1. Mariadason JM. HDACs and HDAC inhibitors in colon cancer. Epigenetics 2008; 3:28-37.
2. Chen L, Fischle W, Verdin E, Greene WC. Duration of nuclear NFkappaB action regulated by reversible acetylation. Science 2001; 293:1653-7.
3. Wilson AJ, Byun DS, Popova N, Murray LB, L'Italien K, Sowa Y, Arango D, Velcich A, Augenlicht LH, Mariadason JM. Histone deacetylase 3 (HDAC3) and other class I HDACs regulate colon cell maturation and p21 expression and are deregulated in human colon cancer. J Biol Chem 2006; 281:13548-58.
4. Spurling CC, Godman CA, Noonan EJ, Rasmussen TP, Rosenberg DW, Giardina C. HDAC3 overexpression and colon cancer cell proliferation and differentiation. Mol Carcinog 2008; 47:137-47.
5. Bhaskara S, Chyla BJ, Amann JM, Knutson SK, Cortez D, Sun ZW, Hiebert SW. Deletion of histone deacetylase 3 reveals critical roles in S phase progression and DNA damage control. Mol Cell 2008; 30:61-72.
6. Zhu CC, Bornemann DJ, Zhitomirsky D, Miller EL, O'Connor MB, Simon JA. Drosophila histone deacetylase-3 controls imaginal disc size through suppression of apoptosis. PLoS Genet 2008; 4:1000009.
7. Godman CA, Joshi R, Tierney BR, Greenspan E, Rasmussen TP, Wang H-W, Shin D-G, Rosenberg DW and Giardina C. HDAC3 impacts multiple oncogenic pathways in colon cancer cells with effects on Wnt and vitamin D signaling. Cancer Bio & Ther 2008; 7.
8. Huang W, Tan D, Wang X, Han S, Tan J, Zhao Y, Lu J, Huang B. Histone deacetylase 3 represses p15(INK4b) and p21(WAF1/cip1) transcription by interacting with Sp1. Biochem Biophys Res Commun 2006; 339:165-71.
9. Weichert W, Roske A, Niesporek S, Noske A, Buckendahl AC, Dietel M, Gekeler V, Boehm M, Beckers T, Denkert C. Class I histone deacetylase expression has independent prognostic impact in human colorectal cancer: specific role of class I histone deacetylases in vitro and in vivo. Clin Cancer Res 2008; 14:1669-77.
10. Wilson AJ, Byun DS, Nasser S, Murray L, Ayyanar K, Arango D, Figueroa M, Melnick A, Kao GD, Augenlicht LH, Mariadason JM. HDAC4 Promotes Growth of Colon Cancer Cells via Repression of p21. Mol Biol Cell 2008.
11. Palmer HG, Larriba MJ, Garcia JM, Ordonez-Moran P, Pena C, Peiro S, Puig I, Rodriguez R, de la Fuente R, Bernad A, Pollan M, Bonilla F, Gamallo C, de Herreros AG, Munoz A. The transcription factor SNAIL represses vitamin D receptor expression and responsiveness in human colon cancer. Nat Med 2004; 10:917-9.
12. Thorne J, Campbell MJ. The vitamin D receptor in cancer. Proc Nutr Soc 2008; 67:115-27.
13. Yang K, Yang W, Mariadason J, Velcich A, Lipkin M, Augenlicht L. Dietary components modify gene expression: implications for carcinogenesis. J Nutr 2005; 135:2710-4.
14. Khanim FL, Gommersall LM, Wood VH, Smith KL, Montalvo L, O'Neill LP, Xu Y, Peehl DM, Stewart PM, Turner BM, Campbell MJ. Altered SMRT levels disrupt vitamin D3 receptor signalling in prostate cancer cells. Oncogene 2004; 23:6712-25.
15. Gregoire S, Xiao L, Nie J, Zhang X, Xu M, Li J, Wong J, Seto E, Yang XJ. Histone deacetylase 3 interacts with and deacetylates myocyte enhancer factor 2. Mol Cell Biol 2007; 27:1280-95.