Effect of Panax ginseng supplementation on biomarkers of glucose tolerance, antioxidant status and oxidative stress in type 2 diabetic subjects: Results of a placebo-controlled human intervention trial

Diabetes, Obesity and Metabolism

Volumn 10, Issue 11, 2008, Pages 1125-1127

  Ma, S W ^a   Benzie, Iris F F ^a   Chu, T T W ^b   Fok, B S P ^b   Tomlinson, B ^b   Critchley, L A H ^b  

^a HONG KONG POLYTECHNIC UNIVERSITY   (Hong Kong)

^b CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

ALLANTOIN; ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; BIOLOGICAL MARKER; GINSENG EXTRACT; GLUCOSE; INSULIN; MALONALDEHYDE; ORAL ANTIDIABETIC AGENT; PLACEBO; URATE;

ADULT; ANTIOXIDANT ACTIVITY; ARTICLE; CARDIOVASCULAR RISK; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DIABETIC DIET; DIET SUPPLEMENTATION; DOUBLE BLIND PROCEDURE; ENZYME LINKED IMMUNOSORBENT ASSAY; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE; GLYCEMIC CONTROL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; IN VITRO STUDY; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; NON INSULIN DEPENDENT DIABETES MELLITUS; ORAL GLUCOSE TOLERANCE TEST; OXIDATIVE STRESS; PROTEIN BLOOD LEVEL; RANDOMIZED CONTROLLED TRIAL; TREATMENT DURATION; VITAMIN BLOOD LEVEL;

EID: 54249148934     PISSN: 14628902     EISSN: 14631326     Source Type: Journal    
DOI: 10.1111/j.1463-1326.2008.00858.x     Document Type: Article

References (12)

1. Vuksan V, Sievenpiper JL, Xu Z et al. Konjac-Mannan and American ginseng: Emerging alternative therapies for type 2 diabetes mellitus. J Am Coll Nutr 2001; 20: 370S-380S; discussion 381S-383S.
2. Vuksan V, Sievenpiper JL. Herbal remedies in the management of diabetes: lessons learned from the study of ginseng. Nutr Metab Cardiovasc Dis 2005; 15: 149-160.
3. Vuksan V, Sung MK, Sievenpiper JL et al. Korean red ginseng (Panax ginseng) improves glucose and insulin regulation in well-controlled, type 2 diabetes: Results of a randomized, double-blind, placebo-controlled study of efficacy and safety. Nutr Metab Cardiovasc Dis 2008; 18: 46-56.
4. Benzie IFF, Strain JJ. Ferric reducing/antioxidant power assay: Direct measure of total antioxidant activity of biological fluids and modified version for simultaneous measurement of total antioxidant power and ascorbate concentration. Methods Enzymol 1999; 299: 15-27.
5. Jentzsch AM, Bachmann H, Furst P, Biesalski HK. Improved analysis of malondialdehyde in human body fluids. Free Radic Biol Med 1996; 20: 251-256.
6. Benzie IFF, Chung WY, Tomlinson B. Simultaneous measurement of allantoin and urate in plasma: Analytical evaluation and potential clinical application in oxidant: Antioxidant balance studies. Clin Chem 1999; 45: 901-904.
7. Brandt RB, Kaugars GE, Riley WT et al. Evaluation of serum and tissue levels of α-tocopherol. Biochem Mol Med 1996; 57: 64-66.
8. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner DC. Homeostasis model assessment: Insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985; 28: 412-419.
9. Park MY, Lee KS, Sung MI. Effects of dietary mulberry, Korean red ginseng, and banaba on glucose homeostasis in relation to PPAR-α, PPAR-γ, and LPL mRNA expressions. Life Sci 2005; 77: 3344-3454.
10. Lee WK, Kao ST, Liu IM, Cheng JT. Increase of insulin secretion by ginsenoside Rh2 to lower plasma glucose in Wistar rats. Clin Exp Pharmacol Physiol 2006; 33: 27-32.
11. Xie JT, Mehendale S, Yuan CS. Ginseng and diabetes. Am J Chin Med 2005; 33: 397-404.
12. Szeto YT, Tomlinson B, Benzie IFF. Total antioxidant and ascorbate content of fresh fruits and vegetables: Implications for dietary planning and food preservation. Br J Nutr 2002; 87: 55-59.