Computationally identified novel diphenyl- and phenylpyridine androgen receptor antagonist structures

Journal of Chemical Information and Modeling

Volumn 48, Issue 9, 2008, Pages 1882-1890

  Söderholm, Annu A ^a,b   Viiliäinen, Johanna ^c   Lehtovuori, Pekka T ^a   Eskelinen, Hanna ^c   Roell, Daniela ^d   Baniahmad, Aria ^c,d   Nyrönen, Tommi H ^a  

^a IT Center for Science   (Finland)

^b ÅBO AKADEMI UNIVERSITY   (Finland)

^c UNIVERSITY OF EASTERN FINLAND   (Finland)

^d FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

3D MODELING; CELL PROLIFERATION; CELLS; COMPUTATIONAL CHEMISTRY; DISEASES; MOLECULAR GRAPHICS; UROLOGY;

ANDROGEN RECEPTOR ANTAGONISTS; ANDROGEN RECEPTORS; ANDROGEN-DEPENDENT; BINDING COMPOUNDS; CHEMICAL DATABASE; INHIBITORY ACTIVITY; PROSTATE CANCER CELLS; VIRTUAL SCREENING;

CYTOLOGY;

ANDROGEN RECEPTOR; ANILIDE; ANTIANDROGEN; ANTINEOPLASTIC AGENT; BICALUTAMIDE; DRUG DERIVATIVE; FLUTAMIDE; HYDROXYFLUTAMIDE; NITRILE; PYRIDINE DERIVATIVE; TOLUENESULFONIC ACID DERIVATIVE;

ANIMAL; ARTICLE; BINDING COMPETITION; CELL CULTURE; CELL PROLIFERATION; CERCOPITHECUS; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER SIMULATION; DRUG ANTAGONISM; DRUG DESIGN; DRUG EFFECT; DRUG SCREENING; HUMAN; MALE; PROSTATE TUMOR; TUMOR CELL LINE;

ANDROGEN ANTAGONISTS; ANILIDES; ANIMALS; ANTINEOPLASTIC AGENTS; BINDING, COMPETITIVE; CELL LINE, TUMOR; CELL PROLIFERATION; CELLS, CULTURED; CERCOPITHECUS AETHIOPS; COMPUTER SIMULATION; DRUG DESIGN; DRUG EVALUATION, PRECLINICAL; DRUG SCREENING ASSAYS, ANTITUMOR; FLUTAMIDE; HUMANS; MALE; MODELS, MOLECULAR; MOLECULAR STRUCTURE; NITRILES; PROSTATIC NEOPLASMS; PYRIDINES; RECEPTORS, ANDROGEN; TOSYL COMPOUNDS;

EID: 54249141064     PISSN: 15499596     EISSN: 1549960X     Source Type: Journal    
DOI: 10.1021/ci800149w     Document Type: Article

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