Genetic markers of IgG influence the outcome of infection with hepatitis C virus

Journal of Infectious Diseases

Volumn 198, Issue 9, 2008, Pages 1334-1336

  Pandey, Janardan P ^a   Namboodiri, Aryan M ^a   Luo, Yuqun ^b   Wu, Yuping ^c   Elston, Robert C ^b   Thomas, David L ^d   Rosen, Hugo R ^f   Goedert, James J ^e  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c CLEVELAND STATE UNIVERSITY   (United States)

^d JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e NATIONAL CANCER INSTITUTE   (United States)

^f UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ALLOTYPE; IMMUNOGLOBULIN G;

ADOLESCENT; ADULT; AGED; ARTICLE; CHILD; CONTROLLED STUDY; DISEASE COURSE; DNA SEQUENCE; FEMALE; GENE FREQUENCY; GENETIC ANALYSIS; GENOTYPE; HEPATITIS C; HEPATITIS C VIRUS; HUMAN; MAJOR CLINICAL STUDY; MALE; MARKER GENE; PRIORITY JOURNAL; RACE DIFFERENCE;

GENETIC MARKERS; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HEPACIVIRUS; HEPATITIS C; HUMANS; IMMUNOGLOBULIN G; IMMUNOGLOBULIN GM ALLOTYPES; IMMUNOGLOBULIN KM ALLOTYPES;

EID: 54249104901     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/592282     Document Type: Article

References (15)

1. Singh R, Kaul R, Kaul A, Khan K. A comparative review of HLA associations with hepatitis B and C viral infections across global populations. World J Gastroenterol 2007;13:1770-87.
2. Oleksyk TK, Thio CL, Truelove AL, et al. Single nucleotide polymorphisms and haplotypes in the IL10 region associated with HCV clearance. Genes Immun 2005;6:347-57.
3. Huang Y, Yang H, Borg BB, et al. A functional SNP of interferon-gamma gene is important for interferon-alpha-induced and spontaneous recovery from hepatitis C virus infection. Proc Natl Acad Sci USA 2007; 104:985-90.
4. Pandey JP, Astemborski J, Thomas DL. Epistatic effects of immunoglobulin GM and KM allotypes on outcome of infection with hepatitis C virus. J Virol 2004;78:4561-5.
5. Grubb R. Advances in human immunoglobulin allotypes. Exp Clin Immunogenet 1995;12:191-7.
6. Balbín M, Grubb A, Abrahamson M, Grubb R. Determination of allotypes G1m (f) and G1m(z) at the genomic level by subclass-specific amplification of DNA and use of allele-specific probes. Exp Clin Immunogenet 1991;8:88-95.
7. Brusco A, de Lange GG, Boccazzi C, Carbonara AO. Molecular characterization of Gm(n+) and G2m(n-) allotypes. Immunogenetics 1995;42:414-7.
8. Moxley G, Gibbs RS. Polymerase chain reaction-based genotyping for allotypic markers of immunoglobulin kappa shows allelic association of Km with kappa variable segment. Genomics 1992;13:104-8.
9. Namboodiri AM, Budkowska A, Nietert PJ, Pandey JP. Fcγ receptor-like hepatitis C virus core protein binds differentially to IgG of discordant Fc (GM) genotypes. Mol Immunol 2007;44:3805-8.
10. Namboodiri AM, Nietert PJ, Pandey JP. Hepatitis C virus core protein discriminates between the two IgG2 allotypes. Viral Immunol 2008;21:273- 6.
11. Maillard P, Lavergne JP, Sibéril S, et al. Fcγ receptor-like activity of hepatitis C virus core protein. J Biol Chem 2004;279:2430-7.
12. Chen M, Sällberg M, Sönnerborg A, et al. Limited humoral immunity in hepatitis C virus infection. Gastroenterology 1999;116:135- 43.
13. Pandey JP, Montes-Cano MA, Aguilar-Reina J, Gonzalez-Escribano MF Interactive effects of immunoglobulin gamma and human leucocyte antigen genotypes on clearance and persistence of infection with hepatitis C virus. Clin Exp Immunol 2007;150:518-22.
14. Martínez A, Sánchez E, Valdivia A, et al. Epistatic interaction between FCRL3 and NFκB1 genes in Spanish patients with rheumatoid arthritis. Ann Rheum Dis 2006;65:1188-91.
15. Pandey JP, Luo Y, Elston RC, et al. Immunoglobulin allotypes influence IgG antibody responses to hepatitis C virus envelope proteins E1 and E2. Hum Immunol 2008;69:158-64.