Peroxisome proliferator-activated receptor delta: A conserved director of lipid homeostasis through regulation of the oxidative capacity of muscle

PPAR Research

Volumn , Issue , 2008, Pages

  De Lange, Pieter ^a   Lombardi, Assunta ^b   Silvestri, Elena ^c   Goglia, Fernando ^c   Lanni, Antonia ^a   Moreno, Maria ^c  

^a SECOND UNIVERSITY OF NAPLES   (Italy)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^c UNIVERSITY OF SANNIO   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

4 [4 [3 (4 ACETYL 3 HYDROXY 2 PROPYLPHENOXY)PROPOXY]PHENOXY]ACETIC ACID; [4 [2 (3 FLUORO 4 TRIFLUOROMETHYLPHENYL) 4 METHYL 5 THIAZOLYLMETHYLTHIO] 2 METHYLPHENOXY]ACETIC ACID; CELL NUCLEUS RECEPTOR; FAT; FATTY ACID; GLUCOSE; GW 1516; GW 610742; LIPID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR AGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; THYROID HORMONE RECEPTOR BETA; UNCLASSIFIED DRUG; UNCOUPLING PROTEIN 3;

ADIPOSE TISSUE; DRUG MECHANISM; GLYCOLYSIS; HOMEOSTASIS; HUMAN; INSULIN RESISTANCE; LIPID HOMEOSTASIS; LIPID METABOLISM; LIPID OXIDATION; LIPOGENESIS; LIPOLYSIS; LIVER METABOLISM; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN METABOLISM; PROTEIN PROTEIN INTERACTION; REVIEW; SKELETAL MUSCLE; WHITE ADIPOSE TISSUE;

EID: 54249088377     PISSN: 16874757     EISSN: 16874765     Source Type: Journal    
DOI: 10.1155/2008/172676     Document Type: Review

References (53)

1. Spiegelman B. M., Flier J. S., Obesity and the regulation of energy balance Cell 2001 104 4 531 543
2. Flück M., Hoppeler H., Molecular basis of skeletal muscle plasticity - from gene to form and function Reviews of Physiology, Biochemistry and Pharmacology 2003 146 159 216
3. Taylor S. I., Deconstructing type 2 diabetes Cell 1999 97 1 9 12
4. Zimmet P., Alberti K. G. M. M., Shaw J., Global and societal implications of the diabetes epidemic Nature 2001 414 6865 782 787
5. de Lange P., Moreno M., Silvestri E., Lombardi A., Goglia F., Lanni A., Fuel economy in food-deprived skeletal muscle: signaling pathways and regulatory mechanisms The FASEB Journal 2007 21 13 3431 3441
6. Fürnsinn C., Willson T. M., Brunmair B., Peroxisome proliferator-activated receptor- δ, a regulator of oxidative capacity, fuel switching and cholesterol transport Diabetologia 2007 50 1 8 17
7. Risérus U., Sprecher D., Johnson T., Activation of peroxisome proliferator-activated receptor (PPAR) δ promotes reversal of multiple metabolic abnormalities, reduces oxidative stress, and increases fatty acid oxidation in moderately obese men Diabetes 2008 57 2 332 339
8. Tanaka T., Yamamoto J., Iwasaki S., Activation of peroxisome proliferator-activated receptor δ induces fatty acid β -oxidation in skeletal muscle and attenuates metabolic syndrome Proceedings of the National Academy of Sciences of the United States of America 2003 100 26 15924 15929
9. Wang Y.-X., Zhang C.-L., Yu R. T., Regulation of muscle fiber type and running endurance by PPAR δ PLoS Biology 2004 2 10, e294 1532 1539
10. Lee C.-H., Olson P., Hevener A., PPAR δ regulates glucose metabolism and insulin sensitivity Proceedings of the National Academy of Sciences of the United States of America 2006 103 9 3444 3449
11. Yan Z. C., Liu D. Y., Zhang L. L., Exercise reduces adipose tissue via cannabinoid receptor type 1 which is regulated by peroxisome proliferator-activated receptor- δ Biochemical and Biophysical Research Communications 2007 354 2 427 433
12. He W., Barak Y., Hevener A., Adipose-specific peroxisome proliferator-activated receptor δ knockout causes insulin resistance in fat and liver but not in muscle Proceedings of the National Academy of Sciences of the United States of America 2003 100 26 15712 15717
13. Berger J., Moller D. E., The mechanisms of action of PPARs Annual Review of Medicine 2002 53 1 409 435
14. Amri E.-Z., Bonino F., Ailhaud G., Abumrad N. A., Grimaldi P. A., Cloning of a protein that mediates transcriptional effects of fatty acids in preadipocytes. Homology to peroxisome proliferator-activated receptors Journal of Biological Chemistry 1995 270 5 2367 2371
15. Braissant O., Foufelle F., Scotto C., Dauça M., Wahli W., Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR- α,-β, and-δ in the adult rat Endocrinology 1996 137 1 354 366
16. Michalik L., Wahli W., Peroxisome proliferator-activated receptors: three isotypes for a multitude of functions Current Opinion in Biotechnology 1999 10 6 564 570
17. Tontonoz P., Hu E., Devine J., Beale E. G., Spiegelman B. M., PPAR γ 2 regulates adipose expression of the phosphoenolpyruvate carboxykinase gene Molecular and Cellular Biology 1995 15 1 351 357
18. de Lange P., Feola A., Ragni M., Differential 3,5, 3 ′ -triiodothyronine-mediated regulation of uncoupling protein 3 transcription: role of fatty acids Endocrinology 2007 148 8 4064 4072
19. Solanes G., Pedraza N., Iglesias R., Giralt M., Villarroya F., Functional relationship between MyoD and peroxisome proliferator-activated receptor-dependent regulatory pathways in the control of the human uncoupling protein-3 gene transcription Molecular Endocrinology 2003 17 10 1944 1958
20. Krey G., Braissant O., L'Horset F., Fatty acids, eicosanoids, and hypolipidemic agents identified as ligands of peroxisome proliferator-activated receptors by coactivator-dependent receptor ligand assay Molecular Endocrinology 1997 11 6 779 791
21. Nolte R. T., Wisely G. B., Westin S., Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor- γ Nature 1998 395 6698 137 143
22. Xu H. E., Lambert M. H., Montana V. G., Molecular recognition of fatty acids by peroxisome proliferator-activated receptors Molecular Cell 1999 3 3 397 403
23. Surapureddi S., Yu S., Bu H., Identification of a transcriptionally active peroxisome proliferator-activated receptor α-interacting cofactor complex in rat liver and characterization of PRIC285 as a coactivator Proceedings of the National Academy of Sciences of the United States of America 2002 99 18 11836 11841
24. Nielsen R., Grøntved L., Stunnenberg H. G., Mandrup S., Peroxisome proliferator-activated receptor subtype- and cell-type-specific activation of genomic target genes upon adenoviral transgene delivery Molecular and Cellular Biology 2006 26 15 5698 5714
25. de Lange P., Ragni M., Silvestri E., Combined cDNA array/RT-PCR analysis of gene expression profile in rat gastrocnemius muscle: relation to its adaptive function in energy metabolism during fasting The FASEB Journal 2004 18 2 350 352
26. Muoio D. M., MacLean P. S., Lang D. B., Fatty acid homeostasis and induction of lipid regulatory genes in skeletal muscles of peroxisome proliferator-activated receptor (PPAR) α knock-out mice. Evidence for compensatory regulation by PPAR δ Journal of Biological Chemistry 2002 277 29 26089 26097
27. Holst D., Luquet S., Nogueira V., Kristiansen K., Leverve X., Grimaldi P. A., Nutritional regulation and role of peroxisome proliferator-activated receptor δ in fatty acid catabolism in skeletal muscle Biochimica et Biophysica Acta 2003 1633 1 43 50
28. Dressel U., Allen T. L., Pippal J. B., Rohde P. R., Lau P., Muscat G. E. O., The peroxisome proliferator-activated receptor β / δ agonist, GW501516, regulates the expression of genes involved in lipid catabolism and energy uncoupling in skeletal muscle cells Molecular Endocrinology 2003 17 12 2477 2493
29. Jucker B. M., Yang D., Casey W. M., Selective PPAR δ agonist treatment increases skeletal muscle lipid metabolism without altering mitochondrial energy coupling: an in vivo magnetic resonance spectroscopy study American Journal of Physiology 2007 293 5 E1256 E1264
30. Wang Y.-X., Lee C.-H., Tiep S., Peroxisome-proliferator-activated receptor δ activates fat metabolism to prevent obesity Cell 2003 113 2 159 170
31. Lin J., Wu H., Tarr P. T., Transcriptional co-activator PGC-1 α drives the formation of slow-twitch muscle fibres Nature 2002 418 6899 797 801
32. Leone T. C., Lehman J. J., Finck B. N., PGC-1 α deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis PLoS Biology 2005 3 4, e101 672 687
33. Schuler M., Ali F., Chambon C., PGC1 α expression is controlled in skeletal muscles by PPAR δ, whose ablation results in fiber-type switching, obesity, and type 2 diabetes Cell Metabolism 2006 4 5 407 414
34. Luquet S., Lopez-Soriano J., Holst D., Peroxisome proliferator-activated receptor δ controls muscle development and oxidative capability The FASEB Journal 2003 17 15 2299 2301
35. Brunmair B., Staniek K., Dörig J., Activation of PPAR- δ in isolated rat skeletal muscle switches fuel preference from glucose to fatty acids Diabetologia 2006 49 11 2713 2722
36. Constantin D., Constantin-Teodosiu D., Layfield R., Tsintzas K., Bennett A. J., Greenhaff P. L., PPAR δ agonism induces a change in fuel metabolism and activation of an atrophy programme, but does not impair mitochondrial function in rat skeletal muscle Journal of Physiology 2007 583 1 381 390
37. Lunde I. G., Ekmark M., Rana Z. A., Buonanno A., Gundersen K., PPAR δ expression is influenced by muscle activity and induces slow muscle properties in adult rat muscles after somatic gene transfer Journal of Physiology 2007 582 3 1277 1287
38. Krämer D. K., Al-Khalili L., Guigas B., Leng Y., Garcia-Roves P. M., Krook A., Role of AMP kinase and PPAR δ in the regulation of lipid and glucose metabolism in human skeletal muscle Journal of Biological Chemistry 2007 282 27 19313 19320
39. Randle P. J., Garland P. B., Hales C. N., Newsholme E. A., The glucose fatty-acid cycle. Its role in isulin sensitivity and the metabolic disturbances of diabetes mellitus The Lancet 1963 281 7285 785 789
40. Escher P., Braissant O., Basu-Modak S., Michalik L., Wahli W., Desvergne B., Rat PPARs: quantitative analysis in adult rat tissues and regulation in fasting and refeeding Endocrinology 2001 142 10 4195 4202
41. Tsintzas K., Jewell K., Kamran M., Differential regulation of metabolic genes in skeletal muscle during starvation and refeeding in humans Journal of Physiology 2006 575 1 291 303
42. Holst D., Luquet S., Nogueira V., Kristiansen K., Leverve X., Grimaldi P. A., Nutritional regulation and role of peroxisome proliferator-activated receptor δ in fatty acid catabolism in skeletal muscle Biochimica et Biophysica Acta 2003 1633 1 43 50
43. de Lange P., Farina P., Moreno M., Sequential changes in the signal transduction responses of skeletal muscle following food deprivation The FASEB Journal 2006 20 14 2579 2581
44. Furuyama T., Kitayama K., Yamashita H., Mori N., Forkhead transcription factor FOXO1 (FKHR)-dependent induction of PDK4 gene expression in skeletal muscle during energy deprivation Biochemical Journal 2003 375, part 2 365 371
45. Sugden M. C., Howard R. M., Munday M. R., Holness M. J., Mechanisms involved in the coordinate regulation of strategic enzymes of glucose metabolism Advances in Enzyme Regulation 1993 33 71 95
46. Lin J., Handschin C., Spiegelman B. M., Metabolic control through the PGC-1 family of transcription coactivators Cell Metabolism 2005 1 6 361 370
47. Watt M. J., Southgate R. J., Holmes A. G., Febbraio M. A., Suppression of plasma free fatty acids upregulates peroxisome proliferator-activated receptor (PPAR) α and δ and PPAR coactivator 1 α in human skeletal muscle, but not lipid regulatory genes Journal of Molecular Endocrinology 2004 33 2 533 544
48. Mahoney D. J., Parise G., Melov S., Safdar A., Tarnopolsky M. A., Analysis of global mRNA expression in human skeletal muscle during recovery from endurance exercise The FASEB Journal 2005 19 11 1498 1500
49. Hood D. A., Invited review: contractile activity-induced mitochondrial biogenesis in skeletal muscle Journal of Applied Physiology 2001 90 3 1137 1157
50. Goodpaster B. H., Katsiaras A., Kelley D. E., Enhanced fat oxidation through physical activity is associated with improvements in insulin sensitivity in obesity Diabetes 2003 52 9 2191 2197
51. Kuhl J. E., Ruderman N. B., Musi N., Exercise training decreases the concentration of malonyl-CoA and increases the expression and activity of malonyl-CoA decarboxylase in human muscle American Journal of Physiology 2006 290 6 E1296 1303
52. Nahlé Z., Hsieh M., Pietka T., CD36-dependent regulation of muscle FoxO1 and PDK4 in the PPAR δ / β -mediated adaptation to metabolic stress The Journal of Biological Chemistry 2008 283 21 14317 14326
53. Ravinet-Trillou C., Delgorge C., Menet C., Arnone M., Soubrié P., CB1 cannabinoid receptor knockout in mice leads to leanness, resistance to diet-induced obesity and enhanced leptin sensitivity International Journal of Obesity 2004 28 4 640 648