An efficient iodine-catalyzed benzylation reaction of 1,3-dicarbonyl compounds

Synlett

Volumn , Issue 16, 2008, Pages 2535-2539

  Li, Zhongxian ^a   Duan, Zheng ^a   Wang, Huaiqiu ^a   Tian, Rongqiang ^a   Zhu, Qianrui ^a   Wu, Yangjie ^a  

^a ZHENGZHOU UNIVERSITY   (China)

Author keywords

Benzylation; C H activation; Catalysis; Friedel Crafts; Iodine

Indexed keywords

1 PHENYLETHANOL; 1,3 DICARBONYL DERIVATIVE; ACETYLACETONE; BENZYL ACETATE; BENZYL ALCOHOL; CARBONYL DERIVATIVE; IODINE; UNCLASSIFIED DRUG;

ARTICLE; BENZYLATION; CATALYSIS; CHEMICAL STRUCTURE; SUBSTITUTION REACTION;

EID: 54249083179     PISSN: 09365214     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2008-1078216     Document Type: Article

References (20)

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18. 2 (2 mL), and molecular iodine (13 mg, 0.05 mmol) were added successively. The mixture was magnetically stirred at 80°C. After completion of the reaction (by GC), the solvent was concentrated under reduced pressure by an aspirator, and the residue was purified by preparative TLC using PE-EtOAc (10:1) as an eluent to afford products.
19. 3): δ = 8.05-8.02 (m, 2 H), 7.74 (d, J = 7.4 Hz, 2 H), 7.57-7.53 (m, 1H)
20. During the preparation of this manuscript, a similar result was reported, see: Srihari, P.; Bhunia, D. C.; Sreedhar, P.; Yadav, J. S. Synlett 2008, 1045.