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54149095190
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54149112090
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US 0249579
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(b) Wang, T.; Kadow, J. F.; Zhang, Z.; Yin, Z.; Meanwell, N. A.; Regueiro-Ren, A.; Swidorski, J.; Han, Y.; Carini, D. J. US 0249579, 2007;
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Wang, T.1
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Zhang, Q.1
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5 reported in: Vilkas, M.; Qasmi, D. Synth. Commun. 1990, 20, 2769.
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5 reported in: Vilkas, M.; Qasmi, D. Synth. Commun. 1990, 20, 2769.
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Kröger, C.-F.1
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12
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54149097295
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US 0272779
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Edwards, L.; Isaac, M.; Johansson, M.; Kers, A.; Malmberg, J.; McLeod, D.; Mindis, A.; Staff, K.; Slassi, A.; Stefanac, T.; Stormann, T.; Wensbo, D.; Xin, T.; Arora, J. US 0272779, 2005;
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54149093090
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Chem. Abstr. 2005, 144, 36353.
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Maffrand, J.-P.; Pereillo, J.-M.; Eloy, F.; Aubert, D.; Rolland, F.; Barthélémy, G. Eur. J. Med. Chem. 1978, 469.
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Maffrand, J.-P.1
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(a) Sitarz, M.; Foks, H.; Janowiec, M.; Augustynowicz-Kopec, E. Chem. Heterocycl. Compd. 2005, 41, 200.
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16
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54149108735
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WO 044192
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(b) Cardoza, M. G.; Powers, J. P.; Goto, H.; Harada, K.; Imamura, K.; Kakutani, M.; Matsuda, I.; Ohe, Y.; Yata, S. WO 044192, 2005;
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Cardoza, M.G.1
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54149093874
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Chem. Abstr. 2005, 142, 482046.
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Chem. Abstr
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18
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54149117963
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For example, see: US 0259862
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For example, see: Wallberg, A.; Nilsson, K.; Holm, B.; Nagard, M.; Granberg, K.; Slassi, A.; Edwards, L.; Isaac, M.; Xin, T.; Stefanac, T. US 0259862, 2007;
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(2007)
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Wallberg, A.1
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Nagard, M.4
Granberg, K.5
Slassi, A.6
Edwards, L.7
Isaac, M.8
Xin, T.9
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19
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54149100484
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Chem. Abstr. 2007, 147, 522250.
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(2007)
Chem. Abstr
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20
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54149088383
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Support was leant to this conclusion by the observation that an analogous preparation of triazolones (R3, aryl or cyclohexyl) did not proceed in the absence of acid. See: Dupin, S, Pesson, M. Bull. Soc. Chim. Fr. 1963, 144
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3 = aryl or cyclohexyl) did not proceed in the absence of acid. See: Dupin, S.; Pesson, M. Bull. Soc. Chim. Fr. 1963, 144.
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21
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0000303126
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This material is commercially available from Alfa Aesar. Its use in the synthesis of thioureas is demonstrated in: Kim, S, Yi, K. Y. Tetrahedron Lett. 1985, 26, 1661
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This material is commercially available from Alfa Aesar. Its use in the synthesis of thioureas is demonstrated in: Kim, S.; Yi, K. Y. Tetrahedron Lett. 1985, 26, 1661.
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22
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54149103246
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This avoided the use of the carcinogenic MeI and gave the S-methylisothiourea as the free base rather than the HI salt thereby allowing for simpler assessment of the role of acid in the cyclisation reaction
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This avoided the use of the carcinogenic MeI and gave the S-methylisothiourea as the free base rather than the HI salt thereby allowing for simpler assessment of the role of acid in the cyclisation reaction.
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23
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0542418948
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For a representative example, see:, John Wiley and Sons: London
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For a representative example, see: Moore, M. L.; Crossley, F. S. Org. Synth., Coll. Vol. III; John Wiley and Sons: London, 1955, 599.
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(1955)
Org. Synth., Coll
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Moore, M.L.1
Crossley, F.S.2
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