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Volumn , Issue 16, 2008, Pages 2421-2424

A convenient synthesis of highly substituted 3-N,N-dialkylamino-1,2,4- triazoles

Author keywords

Cyclisations; Drugs; Heterocycles; Medicinal chemistry; Sulfur

Indexed keywords

AMINOTRIAZOLE; HYDRAZIDE DERIVATIVE; TRIAZOLE DERIVATIVE; UREA DERIVATIVE;

EID: 54149094669     PISSN: 09365214     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2008-1078208     Document Type: Article
Times cited : (22)

References (23)
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    • (2007) Chem. Abstr , vol.147 , pp. 502389
  • 9
    • 84972839054 scopus 로고    scopus 로고
    • 5 reported in: Vilkas, M.; Qasmi, D. Synth. Commun. 1990, 20, 2769.
    • 5 reported in: Vilkas, M.; Qasmi, D. Synth. Commun. 1990, 20, 2769.
  • 13
    • 54149093090 scopus 로고    scopus 로고
    • Chem. Abstr. 2005, 144, 36353.
    • (2005) Chem. Abstr , vol.144 , pp. 36353
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    • 54149093874 scopus 로고    scopus 로고
    • Chem. Abstr. 2005, 142, 482046.
    • (2005) Chem. Abstr , vol.142 , pp. 482046
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    • Chem. Abstr. 2007, 147, 522250.
    • (2007) Chem. Abstr , vol.147 , pp. 522250
  • 20
    • 54149088383 scopus 로고    scopus 로고
    • Support was leant to this conclusion by the observation that an analogous preparation of triazolones (R3, aryl or cyclohexyl) did not proceed in the absence of acid. See: Dupin, S, Pesson, M. Bull. Soc. Chim. Fr. 1963, 144
    • 3 = aryl or cyclohexyl) did not proceed in the absence of acid. See: Dupin, S.; Pesson, M. Bull. Soc. Chim. Fr. 1963, 144.
  • 21
    • 0000303126 scopus 로고    scopus 로고
    • This material is commercially available from Alfa Aesar. Its use in the synthesis of thioureas is demonstrated in: Kim, S, Yi, K. Y. Tetrahedron Lett. 1985, 26, 1661
    • This material is commercially available from Alfa Aesar. Its use in the synthesis of thioureas is demonstrated in: Kim, S.; Yi, K. Y. Tetrahedron Lett. 1985, 26, 1661.
  • 22
    • 54149103246 scopus 로고    scopus 로고
    • This avoided the use of the carcinogenic MeI and gave the S-methylisothiourea as the free base rather than the HI salt thereby allowing for simpler assessment of the role of acid in the cyclisation reaction
    • This avoided the use of the carcinogenic MeI and gave the S-methylisothiourea as the free base rather than the HI salt thereby allowing for simpler assessment of the role of acid in the cyclisation reaction.
  • 23
    • 0542418948 scopus 로고
    • For a representative example, see:, John Wiley and Sons: London
    • For a representative example, see: Moore, M. L.; Crossley, F. S. Org. Synth., Coll. Vol. III; John Wiley and Sons: London, 1955, 599.
    • (1955) Org. Synth., Coll , vol.3 , pp. 599
    • Moore, M.L.1    Crossley, F.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.