메뉴 건너뛰기




Volumn , Issue 16, 2008, Pages 2491-2494

A novel DNA-catalyzed aldol reaction

Author keywords

Aldol reaction; Aqueous buffer; Catalyst; DNA

Indexed keywords

ACETONE; BENZALDEHYDE DERIVATIVE; BUFFER; DIMETHYL SULFOXIDE; DNA; WATER;

EID: 54149093925     PISSN: 09365214     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2008-1078058     Document Type: Article
Times cited : (13)

References (50)
  • 9
  • 24
    • 11844259698 scopus 로고    scopus 로고
    • Mahrwald, R, Ed, Wiley-VCH: Weinheim
    • Modern Aldol Reactions; Mahrwald, R., Ed.; Wiley-VCH: Weinheim, 2004.
    • (2004) Modern Aldol Reactions
  • 26
    • 33645457905 scopus 로고    scopus 로고
    • Dipeptide-catalyzed Aldol reactions can be carried out in water-organic solvent mixtures; see
    • (b) Dipeptide-catalyzed Aldol reactions can be carried out in water-organic solvent mixtures; see: Dziedzic, P.; Zou, W.; Háfren, J.; Córdova, A. Org. Biomol. Chem. 2006, 4, 38.
    • (2006) Org. Biomol. Chem , vol.4 , pp. 38
    • Dziedzic, P.1    Zou, W.2    Háfren, J.3    Córdova, A.4
  • 30
    • 0034654216 scopus 로고    scopus 로고
    • List, B.; Lerner, R. A.; Barba, C. F. III J. Am. Chem. Soc. 2000, 122, 2395.
    • (a) List, B.; Lerner, R. A.; Barba, C. F. III J. Am. Chem. Soc. 2000, 122, 2395.
  • 31
    • 0034812506 scopus 로고    scopus 로고
    • Sakthivel, K.; Notz, W.; Bui, T.; Barbas, C. F. III J. Am. Chem. Soc. 2001, 123, 5260.
    • (b) Sakthivel, K.; Notz, W.; Bui, T.; Barbas, C. F. III J. Am. Chem. Soc. 2001, 123, 5260.
  • 34
    • 0034596452 scopus 로고    scopus 로고
    • Bui, T.; Barbas, C. F. III Tetrahedron Lett. 2000, 41, 6951.
    • (e) Bui, T.; Barbas, C. F. III Tetrahedron Lett. 2000, 41, 6951.
  • 35
    • 0037028924 scopus 로고    scopus 로고
    • Còrdova, A.; Notz, W.; Zhong, G.; Betancort, J. M.; Barbas, C. F. III J. Am. Chem. Soc. 2002, 124, 1842.
    • (f) Còrdova, A.; Notz, W.; Zhong, G.; Betancort, J. M.; Barbas, C. F. III J. Am. Chem. Soc. 2002, 124, 1842.
  • 42
  • 43
  • 49
    • 54149119286 scopus 로고    scopus 로고
    • 2 to afford the corresponding aldol product with high purity.
    • 2 to afford the corresponding aldol product with high purity.
  • 50
    • 54149108163 scopus 로고    scopus 로고
    • Spectroscopic Data for Products All products are known compounds; see refs. 7d,e and 8a,1. 4-Hydroxy-4-phenylbutan-2-one (2a) 1H NMR (300 MHz, CDCl3, δ, 7.36-7.27 (m, 4 H, 5.15 (dd, J1, 3.6 Hz, J2, 8.7 Hz, 1 H, 2.88-2.83 (m, 3 H, 2.19 (s, 3 H, 4-(4-Fluorophenyl)-4-hydroxybutan-2-one(2b) 1H NMR (300 MHz, CDCl3, δ, 8.04 (d, J, 8.1 Hz, 2 H, 7.03 (t, J, 8.7 Hz, 2 H, 5.13 (t, J, 3.6 Hz, 1 H, 2.83 (d, J, 7.5 Hz, 2 H, 2.20 (s, 3 H, 4-(4-Chlorophenyl)-4- hydroxybutan-2-one (2c) 1H NMR (300 MHz, CDCl3, δ, 7.32 (t, J, 4.2 Hz, 2 H, 7.46 (d, J, 8.1 Hz, 2 H, 5.14 (t, J, 4.8 Hz, 1 H, 3.38 (d, J, 1.5 Hz, 1 H, 2.85, 2.81 (m, 2 H, 2.19 (s, 3 H, 4-(4-Bromophenyl)-4-hydroxybutan-2-one (2d) 1H NMR (300 MHz, CDCl3, δ, 7.47 d, J
    • 2 = 8.7 Hz, 4 H), 7.52 (d, J = 8.7 Hz, 4 H), 4.99 (d, J = 7.5 Hz, 1 H), 4.24-4.21 (m, 2 H), 3.87-3.73 (m, 8 H), 3.49-3.46 (m, 1 H), 2.97-2.91 (m, 3 H), 2.57-2.55 (m, 3 H), 2.51-2.45 (m, 3 H).


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.