Anti-atherosclerotic activity of triacsin C, an Acyl-CoA synthetase inhibitor

Journal of Antibiotics

Volumn 61, Issue 5, 2008, Pages 318-321

  Matsuda, Daisuke ^a   Namatame, Ichiji ^a   Ohshiro, Taichi ^a   Ishibashi, Shun ^b   Omura, Satoshi ^a   Tomoda, Hiroshi ^a  

^a KITASATO UNIVERSITY   (Japan)

^b JICHI MEDICAL UNIVERSITY   (Japan)

Author keywords

Acyl CoA synthetase; Atherosclerosis; In vivo; Low density lipoprotein receptor knock out mice; Triacsin C

Indexed keywords

CHOLESTEROL; FATTY ACID; GLUCOSE; LONG CHAIN FATTY ACID COENZYME A LIGASE; LOW DENSITY LIPOPROTEIN RECEPTOR; NATURAL PRODUCT; TRIACSIN C; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; ENZYME INHIBITOR; TRIAZENE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DRUG MECHANISM; ENZYME INHIBITION; FATTY ACID BLOOD LEVEL; GLUCOSE BLOOD LEVEL; KNOCKOUT MOUSE; MOUSE; NONHUMAN; PRIORITY JOURNAL; TREATMENT RESPONSE; TRIACYLGLYCEROL BLOOD LEVEL; ANIMAL; BLOOD; BODY WEIGHT; CHEMISTRY; CHOLESTEROL INTAKE; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; HEART MUSCLE; ISOLATION AND PURIFICATION; METABOLISM; MOUSE MUTANT; PATHOLOGY; STREPTOMYCES; THORACIC AORTA;

MUS;

ANIMALS; AORTA, THORACIC; ATHEROSCLEROSIS; BLOOD GLUCOSE; BODY WEIGHT; CHOLESTEROL; CHOLESTEROL, DIETARY; COENZYME A LIGASES; ENZYME INHIBITORS; FATTY ACIDS, NONESTERIFIED; MICE; MICE, KNOCKOUT; MYOCARDIUM; RECEPTORS, LDL; STREPTOMYCES; TRIAZENES; TRIGLYCERIDES;

EID: 54049157859     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.1038/ja.2008.45     Document Type: Article

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