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Volumn 12, Issue 5A, 2008, Pages 1690-1699

The somatostatin analogue octreotide inhibits angiogenesis in the earliest, but not in advanced, stages of portal hypertension in rats

Author keywords

Angiogenesis; Heme oxygenase; Octreotide; Portal hypertension; Somatostatin

Indexed keywords

DRUG DERIVATIVE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; HEME OXYGENASE 1; NOS3 PROTEIN, RAT; OCTREOTIDE; SOMATOSTATIN; SOMATOSTATIN RECEPTOR; SSTR2 PROTEIN, RAT; VASCULOTROPIN A;

EID: 54049148148     PISSN: 15821838     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1582-4934.2008.00218.x     Document Type: Article
Times cited : (30)

References (30)
  • 2
    • 1542347683 scopus 로고    scopus 로고
    • Anti-VEGF receptor-2 monoclonal antibody prevents portal-systemic collateral vessel formation in portal hypertensive mice
    • Fernandez M, Vizzutti F, Garcia-Pagan JC, Rodes J, Bosch J. Anti-VEGF receptor-2 monoclonal antibody prevents portal-systemic collateral vessel formation in portal hypertensive mice. Gastroenterology. 2004 126 : 886 94.
    • (2004) Gastroenterology. , vol.126 , pp. 886-94
    • Fernandez, M.1    Vizzutti, F.2    Garcia-Pagan, J.C.3    Rodes, J.4    Bosch, J.5
  • 3
    • 20444367984 scopus 로고    scopus 로고
    • Inhibition of VEGF receptor-2 decreases the development of hyperdynamic splanchnic circulation and portal-systemic collateral vessels in portal hypertensive rats
    • Fernandez M, Mejias M, Angermayr B, Garcia-Pagan JC, Rodes J, Bosch J. Inhibition of VEGF receptor-2 decreases the development of hyperdynamic splanchnic circulation and portal-systemic collateral vessels in portal hypertensive rats. J Hepatol. 2005 43 : 98 103.
    • (2005) J Hepatol. , vol.43 , pp. 98-103
    • Fernandez, M.1    Mejias, M.2    Angermayr, B.3    Garcia-Pagan, J.C.4    Rodes, J.5    Bosch, J.6
  • 4
    • 36348935694 scopus 로고    scopus 로고
    • Reversal of portal hypertension and hyper-dynamic splanchnic circulation by combined vascular endothelial growth factor and platelet-derived growth factor blockade in rats
    • Fernandez M, Mejias M, Garcia-Pras E, Mendez R, Garcia-Pagan JC, Bosch J. Reversal of portal hypertension and hyper-dynamic splanchnic circulation by combined vascular endothelial growth factor and platelet-derived growth factor blockade in rats. Hepatology. 2007 46 : 1208 17.
    • (2007) Hepatology. , vol.46 , pp. 1208-17
    • Fernandez, M.1    Mejias, M.2    Garcia-Pras, E.3    Mendez, R.4    Garcia-Pagan, J.C.5    Bosch, J.6
  • 5
    • 0032780823 scopus 로고    scopus 로고
    • Somatostatin and its receptor family
    • Patel YC. Somatostatin and its receptor family. Front Neuroendocrinol. 1999 20 : 157 98.
    • (1999) Front Neuroendocrinol. , vol.20 , pp. 157-98
    • Patel, Y.C.1
  • 6
    • 0036614743 scopus 로고    scopus 로고
    • Somatostatin and analogues in portal hypertension
    • Abraldes JG, Bosch J. Somatostatin and analogues in portal hypertension. Hepatology. 2002 35 : 1305 12.
    • (2002) Hepatology. , vol.35 , pp. 1305-12
    • Abraldes, J.G.1    Bosch, J.2
  • 9
    • 1842471298 scopus 로고    scopus 로고
    • Somatostatin analogues: Multiples roles in cellular proliferation, neoplasia, and angiogenesis
    • Dasgupta P. Somatostatin analogues: Multiples roles in cellular proliferation, neoplasia, and angiogenesis. Pharmacol Ther. 2004 102 : 61 85.
    • (2004) Pharmacol Ther. , vol.102 , pp. 61-85
    • Dasgupta, P.1
  • 12
    • 0041836171 scopus 로고    scopus 로고
    • Development of targeted somatostatin-based antiangiogenic therapy: A review and future perspectives
    • Woltering EA. Development of targeted somatostatin-based antiangiogenic therapy: a review and future perspectives. Cancer Biother Radiopharm. 2003 18 : 601 9.
    • (2003) Cancer Biother Radiopharm. , vol.18 , pp. 601-9
    • Woltering, E.A.1
  • 13
    • 0027287377 scopus 로고
    • Cloned somatostatin receptors: Identification of subtype-selective peptides and demonstration of high affinity binding of linear peptides
    • Raynor K, Murphy WA, Coy DH, Taylor JE, Moreau JP, Yasuda K, Bell GI, Reisine T. Cloned somatostatin receptors: identification of subtype-selective peptides and demonstration of high affinity binding of linear peptides. Mol Pharmacol. 1993 43 : 838 44.
    • (1993) Mol Pharmacol. , vol.43 , pp. 838-44
    • Raynor, K.1    Murphy, W.A.2    Coy, D.H.3    Taylor, J.E.4    Moreau, J.P.5    Yasuda, K.6    Bell, G.I.7    Reisine, T.8
  • 19
    • 0032991092 scopus 로고    scopus 로고
    • Increased heme oxygenase-1 gene expression in liver cells and splanchnic organs from portal hypertensive rats
    • Fernandez M, Bonkovsky HL. Increased heme oxygenase-1 gene expression in liver cells and splanchnic organs from portal hypertensive rats. Hepatology. 1999 29 : 1672 9.
    • (1999) Hepatology. , vol.29 , pp. 1672-9
    • Fernandez, M.1    Bonkovsky, H.L.2
  • 20
    • 0034948624 scopus 로고    scopus 로고
    • Increased heme oxygenase activity in splanchnic organs from portal hypertensive rats: Role in modulating mesenteric vascular reactivity
    • Fernandez M, Lambrecht RW, Bonkovsky HL. Increased heme oxygenase activity in splanchnic organs from portal hypertensive rats: role in modulating mesenteric vascular reactivity. J Hepatol. 2001 34 : 812 7.
    • (2001) J Hepatol. , vol.34 , pp. 812-7
    • Fernandez, M.1    Lambrecht, R.W.2    Bonkovsky, H.L.3
  • 21
    • 33646476506 scopus 로고    scopus 로고
    • Heme oxygenase in portal hypertension and liver disease
    • In: Gines, P., Arroyo, V., Rodes, J., Schrier, R.W., editors. Pathogenesis, Diagnosis, and Treatment. Blackwell Publishing Malden, MA. pp.
    • Lambrecht RW, Fernandez M, Shan Y, Bonkovsky HL. Heme oxygenase in portal hypertension and liver disease. In : Gines P, Arroyo V, Rodes J, Schrier RW, editors. Ascites and Renal Dysfunction in Liver Disease. Pathogenesis, Diagnosis, and Treatment. Blackwell Publishing Malden, MA 2005. pp. 125 36.
    • (2005) Ascites and Renal Dysfunction in Liver Disease. , pp. 125-36
    • Lambrecht, R.W.1    Fernandez, M.2    Shan, Y.3    Bonkovsky, H.L.4
  • 22
    • 33646471962 scopus 로고    scopus 로고
    • Heme oxygenase attenuates oxidative stress and inflammation, and increases VEGF expression in portal hypertensive rats
    • Angermayr B, Mejias M, Gracia-Sancho J, Garcia-Pagan JC, Bosch J, Fernandez M. Heme oxygenase attenuates oxidative stress and inflammation, and increases VEGF expression in portal hypertensive rats. J Hepatol. 2006 44 : 1033 9.
    • (2006) J Hepatol. , vol.44 , pp. 1033-9
    • Angermayr, B.1    Mejias, M.2    Gracia-Sancho, J.3    Garcia-Pagan, J.C.4    Bosch, J.5    Fernandez, M.6
  • 23
    • 34147193115 scopus 로고    scopus 로고
    • NAD(P)H oxidase modulates angiogenesis and the development of por-tosystemic collaterals and splanchnic hyperaemia in portal hypertensive rats
    • Angermayr B, Fernandez M, Mejias M, Gracia-Sancho J, Garcia-Pagan JC, Bosch J. NAD(P)H oxidase modulates angiogenesis and the development of por-tosystemic collaterals and splanchnic hyperaemia in portal hypertensive rats. Gut. 2007 56 : 560 4.
    • (2007) Gut. , vol.56 , pp. 560-4
    • Angermayr, B.1    Fernandez, M.2    Mejias, M.3    Gracia-Sancho, J.4    Garcia-Pagan, J.C.5    Bosch, J.6
  • 26
    • 0038518183 scopus 로고    scopus 로고
    • Somatostatin analogs in rheumatoid arthritis and other inflammatory and immune-mediated condi-tions
    • Paran D, Paran H. Somatostatin analogs in rheumatoid arthritis and other inflammatory and immune-mediated condi-tions. Curr Opin Invest Drugs. 2003 4 : 578 82.
    • (2003) Curr Opin Invest Drugs. , vol.4 , pp. 578-82
    • Paran, D.1    Paran, H.2
  • 28
    • 0032878565 scopus 로고    scopus 로고
    • Heme oxyge-nase: Recent advances in understanding its regulation and role
    • Elbirt KK, Bonkovsky HL. Heme oxyge-nase: recent advances in understanding its regulation and role. Proc Assoc Am Physicians. 1999 111 : 438 47.
    • (1999) Proc Assoc Am Physicians. , vol.111 , pp. 438-47
    • Elbirt, K.K.1    Bonkovsky, H.L.2
  • 29
    • 0038001984 scopus 로고    scopus 로고
    • Vascular endothelial growth factor increases heme oxygenase-1 protein expression in the chick embryo chorioallantoic membrane
    • Fernandez M, Bonkovsky HL. Vascular endothelial growth factor increases heme oxygenase-1 protein expression in the chick embryo chorioallantoic membrane. Br J Pharmacol. 2003 139 : 634 40.
    • (2003) Br J Pharmacol. , vol.139 , pp. 634-40
    • Fernandez, M.1    Bonkovsky, H.L.2
  • 30
    • 0029097260 scopus 로고
    • Effects of bolus injections and continuous infusions of somatostatin and placebo in patients with cirrhosis: A double-blind hemodynamic investigation
    • Cirera I, Feu F, Luca A, Garcia-Pagan JC, Fernandez M, Escorsell A, Bosch J, Rodes J. Effects of bolus injections and continuous infusions of somatostatin and placebo in patients with cirrhosis: a double-blind hemodynamic investigation. Hepatology. 1995 22 : 106 11.
    • (1995) Hepatology. , vol.22 , pp. 106-11
    • Cirera, I.1    Feu, F.2    Luca, A.3    Garcia-Pagan, J.C.4    Fernandez, M.5    Escorsell, A.6    Bosch, J.7    Rodes, J.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.