In the ventral tegmental area, progestogens' membrane-mediated actions for lordosis of rats involve the second-messenger phospholipase C

Brain Research

Volumn 1230, Issue , 2008, Pages 218-223

  Frye, Cheryl A ^a   Walf, Alicia A ^a  

^a STATE UNIVERSITY OF NEW YORK   (United States)

Author keywords

5 pregnan 3 ol 20 one; cAMP; Dopamine type 1 receptors; Neurosteroids; Protein kinase C

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; 2,3,4,5 TETRAHYDRO 7,8 DIHYDROXY 1 PHENYL 1H 3 BENZAZEPINE; 3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; 4 AMINOBUTYRIC ACID A RECEPTOR; DOPAMINE 1 RECEPTOR; DRUG VEHICLE; GESTAGEN; MUSCIMOL; PHOSPHOLIPASE C;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR DISORDER; DRUG INFUSION; DRUG MECHANISM; DRUG POTENTIATION; ENZYME INHIBITION; FEMALE; LOCOMOTION; LORDOSIS; MALE; NONHUMAN; OVARIECTOMY; PRIORITY JOURNAL; RAT; SECOND MESSENGER; SIGNAL TRANSDUCTION; VENTRAL TEGMENTUM;

RATTUS; RODENTIA;

EID: 54049143799     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2008.07.027     Document Type: Article

References (34)

1. Akin, D., Manier, D.H., Sanders-Bush, E., Shelton, R.C., 2005. Signal transduction abnormalities in melancholic depression. Int. J. Neuropsychopharmacol. 8, 5-16.
2. Beyer, C., Canchola, E., Larsson, K., 1981. Facilitation of lordosis behavior in the ovariectomised estrogen-primed rat by dibutyryl cAMP. Physiol. Behav. 26, 249-251.
3. Bryant, D.N., Sheldahl, L.C., Marriott, L.K., Shapiro, R.A., Dorsa, D.M., 2006. Multiple pathways transmit neuroprotective effects of gonadal steroids. Endocrine 29, 199-207.
4. Dwivedi, Y., Conley, R.R., Roberts, R.C., Tamminga, C.A., Pandey, G.N., 2002. [(3) H]cAMP binding sites and protein kinase a activity in the prefrontal cortex of suicide victims. Am. J. Psych. 159, 66-73.
5. Fancsik, A., Linn, D.M., Tasker, J.G., 2000. Neurosteroid modulation of GABA IPSCs is phosphorylation dependent. J. Neurosci. 20, 3067-3075.
6. Frye, C.A., 2001. The role of neurosteroids and non-genomic effects of progestins and androgens in mediating sexual receptivity of rodents. Brain Res. Brain Res. Rev. 37, 201-222.
7. Frye, C.A., 2007. Some rewarding effects of androgens may be mediated by actions of its 5a-reduced metabolite 3a-androstanediol. Pharmacol. Biochem. Behav. 86, 354-367.
8. Frye, C.A., 2007. Neurosteroids - From Basic Research to Clinical Perspectives. Editors: Robert T. Rubin and Donald W. Pfaff.
9. Frye, C.A., Mermelstein, P.G., DeBold, J.F., 1992. Evidence for a non-genomic action of progestins on sexual receptivity in hamster ventral tegmental area but not hypothalamus. Brain Res. 578, 87-93.
10. A receptors. In: Watson, C.S. (Ed.), The Identities of Membrane Steroid Receptors: and Other Proteins Mediating Nongenomic Steroid Action. Kluwer Academic Publishers, Boston, MA.
11. Frye, C.A., Rhodes, M.E., Petralia, S.M., Walf, A.A., Sumida, K., Edinger, K.L., 2006. 3a-hydroxy-5a-pregnan-20-one in the midbrain ventral tegmental area mediates social sexual and affective behaviors. Neurosci. 138, 1007-1014.
12. Frye, C.A., Walf, A.A., 2007. In the ventral tegmental area, progestins' membrane-mediated actions for lordosis of hormone-primed hamsters involve phospholipase C and protein kinase C. J. Neuroendo. 19, 717-724.
13. A receptors involve downstream signal transduction pathways. Steroids 73, 906-913.
14. Girault, J.A., Greengard, P., 2004. The neurobiology of dopamine signaling. Arch. Neurol. 61, 641-644.
15. Gonzalez-Flores, O., Ramirez-Orduna, J.M., Lima-Hernandez, F.J., Garcia-Juarez, M., Beyer, C., 2006. Differential effect of kinase A and C blockers on lordosis facilitation by progesterone and its metabolites in ovariectomised estrogen-primed rats. Horm. Behav. 49, 398-404.
16. Hull, E.M., Dominguez, J.M., 2006. Getting his act together: roles of glutamate, nitric oxide, and dopamine in the medial preoptic area. Brain Res. 1126 (1), 66-75.
17. Kow, L.M., Mobbs, C.V., Pfaff, D.W., 1994. Roles of second-messenger systems and neuronal activity in the regulation of lordosis by neurotransmitters, neuropeptides, and estrogen: a review. Neurosci. Biobehav. Rev. 18, 251-268.
18. - channels in a multiphasic manner in embryonic rat hippocampal neurones. J. Neurophysiol. 88, 1147-1158.
19. Liu, M., Simon, M.I., 1996. Regulation by cAMP-dependent protein kinase of a G-protein-mediated phospholipase C. Nature 382, 83-87.
20. Majerus, P.W., Ross, T.S., Cunningham, T.W., Caldwell, K.K., Jefferson, A.B., Bansal, V.S., 1990. Recent insights in phosphatidylinositol signaling. Cell 63, 459-465.
21. Marazziti, D., Perez, J., Cassano, G.B., 2001. Is obsessive-compulsive disorder caused by a second-messenger imbalance? CNS Spectrums 6, 206-209.
22. Mobbs, C.V., Kaplitt, M., Kow, L.M., Pfaff, D.W., 1991. PLC-a: a common mediator of the action of estrogen and other hormones? Mol. Cell. Endocrinol. 80, C187-C191.
23. Pandey, G.N., Dwivedi, Y., Sridhararao, J., Ren, X., Janicak, P.G., Sharma, R., 2002. Protein kinase C and phospholipase C activity and expression of their specific isozymes is decreased and expression of MARCKS is increased in platelets of bipolar but not inunipolar patients. Neuropsychopharmacology 26, 216-228.
24. Paxinos, G., Watson, C., 1986. The Rat Brain. Academic Press, New York.
25. Petralia, S.M., Frye, C.A., 2006. In the ventral tegmental area, G-proteins mediate progesterone's actions at dopamine type 1 receptors for lordosis of rats and hamsters. Psychopharmacol. 186, 133-142.
26. Rausch, J.L., Gillespie, C.F., Fei, Y., Hobby, H.M., Stoming, T., Ganapathy, V., Leibach, F.H., 2002. Antidepressant effects on kinase gene expression patterns in rat brain. Neurosci. Lett. 334, 91-94.
27. Rønnekleiv, O.K., Kelly, M.J., 2005. Diversity of ovarian steroid signaling in the hypothalamus. Front.Neuroendocrinol 26, 65-84.
28. Sherwin, B.B., 2007. The clinical relevance of the relationship between estrogen and cognition in women. J. Steroid Biochem. Mol. Biol. 106, 151-156.
29. Sinchak, K., Dewing, P., Cook, M., Micevych, P., 2007. Release of orphanin FQ/nociceptin in the medial preoptic nucleus and ventromedial nucleus of the hypothalamus facilitates lordosis. Horm. Behav. 51, 406-412.
30. Uphouse, L., Maswood, S., Jackson, A., 2000. Factors elevating cAMP attenuate the effects of 8-OH-DPAT on lordosis behavior. Pharmacol. Biochem. Behav. 66, 383-388.
31. Walf, A.A., Frye, C.A., 2008. Rapid and estrogen receptor b mediated actions in the hippocampus mediate some functional effects of estrogen. Steroids 73, 997-1007.
32. Zhu, Y., Bond, J., Thomas, P., 2003a. Identification, classification, and partial characterization of genes in humans and other vertebrates homologous to a fish membrane progestin receptor. Proc. Natl. Acad. Sci. U. S. A. 100, 2237-2242.
33. Zhu, Y., Rice, C.D., Pang, Y., Pace, M., Thomas, P., 2003b. Cloning, expression, and characterization of a membrane progestin receptor and evidence it is an intermediary in meiotic maturation of fish oocytes. Proc. Natl. Acad. Sci. U. S. A. 100, 2231-2236.
34. Frye, C.A., Duffy, C.K., Walf, A.A., 2007. Estrogens and progestins enhance spatial learning of intact and ovariectomized rats in the object placement task. Neurobiol. Learn. Mem. 88, 208-216.