Donor ethnicity influences outcomes following deceased-donor kidney transplantation in black recipients

Journal of the American Society of Nephrology

Volumn 19, Issue 10, 2008, Pages 2011-2019

  Locke, Jayme E ^a   Warren, Daniel S ^a,c   Dominici, Francesca ^a   Cameron, Andrew M ^a   Leffell, M Sue ^b   McRann, Deborah A ^a   Melancon, J Keith ^a   Segev, Dorry L ^a   Simpkins, Christopher E ^a   Singer, Andrew L ^a   Zachary, Andrea A ^b   Montgomery, Robert A ^a  

^a JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^b DEPARTMENT OF PATHOLOGY   (United States)

^c Ross Research Building   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; CONTROLLED STUDY; ETHNICITY; FEMALE; GRAFT FAILURE; GRAFT RECIPIENT; GRAFT SURVIVAL; HEART DEATH; HUMAN; KIDNEY DONOR; KIDNEY GRAFT; KIDNEY TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; CADAVER; CAUCASIAN; COHORT ANALYSIS; DONOR; ETHNOLOGY; KIDNEY DISEASE; MIDDLE AGED; MORTALITY; NEGRO; RETROSPECTIVE STUDY; RISK FACTOR; STATISTICS; SURVIVAL RATE; TREATMENT OUTCOME;

ADULT; AFRICAN CONTINENTAL ANCESTRY GROUP; CADAVER; COHORT STUDIES; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GRAFT SURVIVAL; HUMANS; KIDNEY DISEASES; KIDNEY TRANSPLANTATION; MALE; MIDDLE AGED; RETROSPECTIVE STUDIES; RISK FACTORS; SURVIVAL RATE; TISSUE DONORS; TREATMENT OUTCOME;

EID: 54049143674     PISSN: 10466673     EISSN: 15333450     Source Type: Journal    
DOI: 10.1681/ASN.2008010078     Document Type: Article

References (37)

1. United States Census Bureau: Census 2000 Brief and National Population Estimates, Washington, DC, United States Census Bureau, March 2001
2. United States Renal Data System: Excerpts from the United States Renal Data System 2004 annual data report. Am J Kidney Dis 45: S1-S270, 2005
3. Barger BO, Hudson SL, Shroyer TW, Deierhoi MH, Barber WH, Curtis JJ, Julian BA, Luke RG, Diethelm AG: Influence of race on renal allograft survival in the pre- and postcyclosporine era. Clin Transpl 217-233, 1987
4. Benfield MR, McDonald RA, Bartosh S, Ho PL, Harmon W: Changing trends in pediatric transplantation: 2001 Annual Report of the North American Pediatric Renal Transplant Cooperative Study. Pediatr Transplant 7: 321-335, 2003
5. Gaston RS, Benfield M: The relationship between ethnicity and outcomes in solid organ transplantation. J Pediatr 147: 721-723, 2005
6. Gjertson DW: Short- and long-term effects of HLA matching. Clin Transpl 353-360, 1989
7. Katznelson S, Gjertson DW, Cecka JM: The effect of race and ethnicity on kidney allograft outcome. Clin Transpl 379-394, 1995
8. Light JA, Barhyte DY, Lahman L: Kidney transplants in African Americans and non-African Americans: Equivalent outcomes with living but not deceased donors. Transplant Proc 37: 699-700, 2005
9. Ojo AO, Port FK, Held PJ, Wolfe RA, Turenne MN, Chung E, Mauger EA, Leichtman AB: Inferior outcome of two-haplotype matched renal transplants in blacks: Role of early rejection. Kidney Int 48: 1592-1599, 1995
10. Opelz G, Pfarr E, Engelmann A, Keppel E: Kidney graft survival rates in black cyclosporine-treated recipients. Collaborative Transplant Study. Transplant Proc 21: 3918-3920, 1989
11. Press R, Carrasquillo O, Nickolas T, Radhakrishnan J, Shea S, Barr RG: Race/ethnicity, poverty status, and renal transplant outcomes. Transplantation 80: 917-924, 2005
12. Young CJ, Gaston RS: Renal transplantation in black Americans. N Engl J Med 343: 1545-1552, 2000
13. Young CJ, Gaston RS: African Americans and renal transplantation: Disproportionate need, limited access, and impaired outcomes. Am J Med Sci 323: 94-99, 2002
14. Chakkera HA, O'Hare AM, Johansen KL, Hynes D, Stroupe K, Colin PM, Chertow GM: Influence of race on kidney transplant outcomes within and outside the Department of Veterans Affairs. J Am Soc Nephrol 16: 269-277, 2005
15. Swanson SJ, Hypolite IO, Agodoa LY, Batty DS, Hshieh PB, Cruess D, Kirk AD, Peters TG, Abbott KC: Effect of donor factors on early graft survival in adult cadaveric renal transplantation. Am J Transplant 2: 68-75, 2002
16. Institute of Medicine: Non-Heart-Beating Organ Transplantation: Practice and Protocols, Washington, DC, National Academy Press, 2000
17. Ethics Committee, American College of Critical Care Medicine, Society of Critical Care Medicine: Recommendations for nonheartbeating organ donation: A position paper by the Ethics Committee, American College of Critical Care Medicine, Society of Critical Care Medicine. Crit Care Med 29: 1826-1831, 2001
18. Cecka JM: Donors without a heartbeat. N Engl J Med 347: 281-283, 2002
19. Cho YW, Terasaki PI, Cecka JM, Gjertson DW: Transplantation of kidneys from donors whose hearts have stopped beating. N Engl J Med 338: 221-225, 1998
20. Evans RW: Kidney transplantation from donors without a heartbeat. N Engl J Med 347: 1799-1801, author reply 1799-801, 2002
21. Abt PL, Fisher CA, Singhal AK: Donation after cardiac death in the US: History and use. J Am Coll Surg 203: 208-225, 2006
22. Doshi MD, Hunsicker LG: Short- and long-term outcomes with the use of kidneys and livers donated after cardiac death. Am J Transplant 7: 122-129, 2007
23. Rudich SM, Kaplan B, Magee JC, Arenas JD, Punch JD, Kayler LK, Merion RM, Meier-Kriesche HU: Renal transplantations performed using non-heart-beating organ donors: Going back to the future? Transplantation 74: 1715-1720, 2002
24. Locke JE, Segev DL, Warren DS, Dominici F, Simpkins CE, Montgomery RA: Outcomes of kidneys from donors after cardiac death: Implications for allocation and preservation. Am J Transplant 7: 1797-1807, 2007
25. Curtis JJ: Kidney transplantation: Racial or socioeconomic disparities? Am J Kidney Dis 34: 756-758, 1999
26. Isaacs RB, Nock SL, Spencer CE, Connors AF, Wang XQ, Sawyer R, Lobo PI: Racial disparities in renal transplant outcomes. Am J Kidney Dis 34: 706-712, 1999
27. Kerman RH, Kimball PM, Van Buren CT, Lewis RM, Cavazos D, Heydari A, Kahan BD: Influence of race on crossmatch outcome and recipient eligibility for transplantation. Transplantation 53: 64-67, 1992
28. Kerman RH, Kimball PM, Van Buren CT, Lewis RM, Kahan BD: Possible contribution of pretransplant immune responder status to renal allograft survival differences of black versus white recipients. Transplantation 51: 338-342, 1991
29. Leffell MS, Steinberg AG, Bias WB, Machan CH, Zachary AA: The distribution of HLA antigens and phenotypes among donors and patients in the UNOS registry. Transplantation 58: 1119-1130, 1994
30. Schweizer RT, Rovelli M, Palmeri D, Vossler E, Hull D, Bartus S: Noncompliance in organ transplant recipients. Transplantation 49: 374-377, 1990
31. Woodward RS, Schnitzler MA, Lowell JA, Spitznagel EL, Brennan DC: Effect of extended coverage of immunosuppressive medications by Medicare on the survival of cadaveric renal transplants. Am J Transplant 1: 69-73, 2001
32. Kusaka M, Yamada K, Kuroyanagi Y, Terauchi A, Kowa H, Kurahashi H, Hoshinaga K: Genomewide expression profiles of rat model renal isografts from brain dead donors. Transplant Proc 83: 62-70, 2007
33. Nijboer WN, Schuurs TA, van der Hoeven JA, Fekken S, Wiersema-Buist J, Leuvenink HG, Hofker S, Homan van der Heide JJ, van Son WJ, Ploeq RJ: Effect of brain death on gene expression and tissue activation in human donor kidneys. Transplantation 78: 978-986, 2004
34. Smith RS, Meyers DA, Peters SP, Moore WC, Wenzel SA, Bleecker ER, Hawkins GA: Sequence analysis of HSPA1A and HSPA1B in a multiethnic study population. DNA Seq 18: 47-53, 2007
35. Glauser TA, Titanic-Schefft M, Pippenger CE: Racial differences in free radical scavenging enzyme activity in children. J Child Neurol 14: 382-387, 1999
36. Grambsch PM, Therneau TM: Proportional hazards tests and diagnostics based on weighted residuals. Biometrika 81: 515-526, 1994
37. May S, Hosmer DW: A simplified method of calculating an overall goodness-of-fit test for the Cox proportional hazards model. Lifetime Data Anal 4: 109-120, 1998