The apolipoprotein E ε4 allele and memory performance in HIV-1 seropositive subjects: Differences at baseline but not after acute oral lorazepam challenge

Psychopharmacology

Volumn 201, Issue 1, 2008, Pages 125-135

  Pomara, Nunzio ^a,b   Belzer, Kenneth D ^a   Silva, Raul ^a,b   Cooper, Thomas B ^a   Sidtis, John J ^a,b  

^a NATHAN S KLINE INSTITUTE FOR PSYCHIATRIC RESEARCH   (United States)

^b NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

AIDS; ApoE 4; ApoE polymorphism; Benzodiazepines; HIV; Lorazepam; Memory

Indexed keywords

APOLIPOPROTEIN E; APOLIPOPROTEIN E EPSILON4; LORAZEPAM; UNCLASSIFIED DRUG; APOLIPOPROTEIN E4; CENTRAL NERVOUS SYSTEM AGENTS;

ADULT; ALLELE; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; COGNITIVE DEFECT; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; FEMALE; GENETIC POLYMORPHISM; HETEROZYGOTE; HIGH RISK POPULATION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MALE; MEMORY DISORDER; PRIORITY JOURNAL; PROVOCATION TEST; RECALL; RISK FACTOR; TASK PERFORMANCE; AGED; BLOOD; CHEMISTRY; COMPARATIVE STUDY; DOSE RESPONSE; DRUG EFFECT; GENETICS; LANGUAGE TEST; LEARNING; MIDDLE AGED; ORAL DRUG ADMINISTRATION; PATHOPHYSIOLOGY; PHYSIOLOGY; PLASMA; PSYCHOMOTOR PERFORMANCE; RANDOMIZED CONTROLLED TRIAL; STATISTICS; VIROLOGY;

ADMINISTRATION, ORAL; ADULT; AGED; ALLELES; APOLIPOPROTEIN E4; CENTRAL NERVOUS SYSTEM AGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; FEMALE; HIV SEROPOSITIVITY; HUMANS; LANGUAGE TESTS; LORAZEPAM; MALE; MENTAL RECALL; MIDDLE AGED; PLASMA; PSYCHOMOTOR PERFORMANCE; RISK FACTORS; VERBAL LEARNING;

EID: 54049139542     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00213-008-1253-1     Document Type: Article

References (37)

1. DM Alexander LM Williams JM Gatt C Dobson-Stone SA Kuan EG Todd PR Schofield NJ Cooper E Gordon 2007 The contribution of apolipoprotein E alleles on cognitive performance and dynamic neural activity over six decades Biol Psychol 75 229 238
2. American Psychiatric Association (1994) Diagnostic and statistical manual of mental disorders, 4th edn. American Psychiatric Press, Washington, DC
3. RI Block R Berchou 1984 Alprazolam and lorazepam effects on memory acquisition and retrieval processes Pharmacol Biochem Behav 20 233 241
4. H Buschke 1973 Selective reminding for analysis of memory and learning J Verb Learn Verb Behav 12 543 550
5. H Buschke 1974 Retrieval in human learning Trans NY Acad Sci 36 721 729
6. RJ Cascelli EM Reiman JG Hentz D Osborne GE Alexander BF Boeve 2002 A distinctive interaction between memory and chronic daytime somnolence in asymptomatic APOE e4 homozygotes Sleep 25 447 453
7. Center for Disease Control and Prevention 1992 1993 Revised classification system for HIV infection and expanded surveillance case definition for AIDS among adolescents and adults Morb Mort Wkly Rep 41 RR-17 1 18
8. JG Chen CL Edwards S Vidyarthi S Pitchumoni S Tabrizi D Barboriak HC Charles PM Doraiswami 2002 Learning and recall in subjects at genetic risk for Alzheimer's disease J Neuropsychiatry Clin Neurosci 14 58 63
9. N Cherbuin LS Leach H Christensen KJ Anstey 2007 Neuroimaging and APOE genotype: a systematic qualitative review Dement Geriatr Cogn Disord 24 348 362
10. E Corder K Robertson L Lannfelt N Bogdanovic G Eggertsen J Wilkins C Hall 1998 HIV-infected subjects with the E4 allele for APOE have excess dementia and peripheral neuropathy Nat Med 4 1182 1184
11. O Dunlop AK Goplen K Liestol B Myrvang H Rootwell B Christophersen EA Dvittingen J Maehlen 1997 HIV dementia and apolipoprotein E Acta Neurol Scand 95 315 318
12. MF Folstein SE Folstein PR McHugh 1975 "Mini-Mental State": a practical method for grading the cognitive state of patients for the clinician J Psychiatr Res 12 189 198
13. D Green E Masliah H Vinters P Beizai D Moore C Achim 2005 Brain deposition of beta-amyloid is a common pathologic feature in HIV positive patients AIDS 19 407 411
14. DJ Greenblatt LL Von Moltke JS Harmatz AL Durol JP Daily JA Graf P Mertzanis JL Hoffman Sh RI ader 2000 Alprazolam-ritonavir interaction: implications for product labeling Clin Pharmacol Ther 67 335 341
15. M Hamilton 1959 The assessment of anxiety states by rating Br J Med Psychol 32 50 55
16. M Hamilton 1967 Development of a rating scale for primary depressive illness Br J Soc Clin Psychol 6 278 296
17. SD Han AI Drake LM Cessante AJ Jak WS Houston DC Delis JV Filoteo MW Bondi 2007 Apolipoprotein E and traumatic brain injury in a military population: evidence of neuropsychological compensatory mechanism? J Neurol Neurosurg Psychiatry 78 1103 1108
18. JE Hixson DT Vernier 1990 Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with HhaI J Lipid Res 31 545 548
19. AF Jorm KA Mather P Butterworth KJ Anstey H Christensen J Easteal 2007 APOE Genotype and cognitive functioning in a large age-stratified population sample Neuropsychol 21 1 8
20. S Kataoka M Paidi BV Howard 1994 Simplified isoelectric focusing/immunoblotting determination of apolipoprotein E phenotype Clin Chem 40 11 3
21. RW Mahley KH Weisgraber Y Huang 2006 Apolipoprotein E4: a causative factor and therapeutic target in neuropathology, including Alzheimer's disease PNAS 103 5644 5651
22. CRA Mondadori JF de Quervain A Buchmann H Mustovic MA Wollmer CF Schmidt P Boesiger C Hock RM Nitsch A Papassotiropoulos K Henke 2007 Better memory and neural efficiency in young apolipoprotein E e4 carriers Cereb Cortex 17 1934 1947
23. J Nierenberg N Pomara MJ Hoptman JJ Sidtis BA Ardekani KO Lim 2005 Abnormal white matter integrity in healthy apolipoprotein E epsilon4 carriers Neuroreport 16 1369 1372
24. R O'Hara JA Yesavage HC Kraemer M Mauricio LF Friedman GM Murphy 1998 The APOE epsilon4 allele is associated with decline on delayed recall performance in community-dwelling older adults J Am Geriatr Soc 46 1493 1498
25. N Pomara H Tun D DaSilva R Hernando D Deptula DJ Greenblatt 1998 The acute and chronic performance effects of alprazolam and lorazepam in the elderly: relationship to duration of treatment and self-rated sedation Psychopharmacol Bull 134 139 153
26. N Pomara LM Willoughby K Wesnes DJ Greenblatt JJ Sidtis 2005 Apolipoprotein E epsilon 4 allele and lorazepam effects on memory in high functioning older adults Arch Gen Psychiatry 62 209 216
27. RW Price B Brew JJ Sidtis M Rosenblum AC Scheck P Cleary 1988 The brain in AIDS: central nervous system HIV-1 infection and the AIDS dementia complex Science 239 586 592
28. EM Reiman FJ Caselli K Chen GE Alexander D Bandy J Frost 2001 Declining brain activity in cognitively normal apolipoprotein E epsilon 4 heterozygotes: a foundation for using positron emission tomography to efficiently test treatments to prevent Alzheimer's disease Proc Natl Acad Sci U S A 98 3334 3339
29. GW Small ST Chen S Komo L Ercoli S Bookheimer K Miller H Lavretsky S Saxena A Kaplan D Dorsey WK Scott AM Saunders JL Haines AD Roses MA Pericak-Vance 1999 Memory self-appraisal in middle-aged and older adults with the apolipoprotein E-4 allele Am J Psychiatry 156 1035 1038
30. SPSS (2006) SPSS 15.0 for Windows [computer program] release 15.0. SPSS Incorporated, Chicago, IL
31. BE Tardiff MF Newman AM Saunders WJ Strittmatter JA Blumenthal WD White ND Croughwell RD Davis AD Roses JG Reves 1997 Preliminary report of a genetic basis for cognitive decline after cardiac operations. The Neurologic outcome research group of the Duke Heart Center Ann Thorac Surg 64 715 720
32. Tiffin J (1968) Purdue pegboard: examiner manual. Science Research Associates, Chicago, Il
33. J Turchan-Cholewo Y Liu S Gartner R Reid C Jie X Peng KC Chen A Chauhan N Haughey R Cutler MP Mattson C Pardo K Conant N Sacktor JC McArthur KF Hauser C Gairola A Nath 2006 Increased vulnerability of ApoeE4 neurons to HIV proteins and poiates: protection by diosgenin and l-deprenyl Neurobiol Dis 23 109 119
34. V Valcour C Shikuma B Shiramizu M Watters P Poff OA Selnes J Grove Y Liu K Abdul-Majid S Gartner N Sacktor 2004 Age, apolipoprotein E4, and the risk of HIV dementia: the Hawaii aging with HIV cohort J Neuroimmunol 157 197 202
35. B Vitiello M Burnam E Ging R Beckman M Shapiro 2003 Use of psychotropic medications among HIV-infected patients in the United States Am J Psychiatry 160 547 554
36. RJ Walters JA Nicoll 2005 Genetic influences on outcome following acute neurological insults Curr Opin Crit Care 11 105 10
37. Wechsler D (1981) Wechsler Adult Intelligence Scale-Revised. The Psychological Corporation, San Antonio, TX