Quantification of urinary light chains

Clinical Chemistry

Volumn 54, Issue 10, 2008, Pages 1744-1746

  Snyder, Melissa R ^a   Clark, Raynell ^a   Bryant, Sandra C ^a   Katzmann, Jerry A ^a,b  

^a Mayo Clinic   (United States)

^b MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN LIGHT CHAIN;

AGAR GEL ELECTROPHORESIS; AMYLOIDOSIS; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST; HUMAN; LABORATORY DIAGNOSIS; LETTER; MAJOR CLINICAL STUDY; MONOCLONAL IMMUNOGLOBULINEMIA; MULTIPLE MYELOMA; PATIENT MONITORING; PROTEIN ANALYSIS; PROTEIN ELECTROPHORESIS; PROTEIN URINE LEVEL; URINALYSIS; ADULT; REFERENCE VALUE; SENSITIVITY AND SPECIFICITY; URINE;

ADULT; HUMANS; IMMUNOGLOBULIN LIGHT CHAINS; REFERENCE VALUES; SENSITIVITY AND SPECIFICITY;

EID: 54049139265     PISSN: 00099147     EISSN: None     Source Type: Journal    
DOI: 10.1373/clinchem.2008.107599     Document Type: Letter

References (5)

1. Rajkumar SV, Dispenzieri A, Kyle RA. Monoclonal gammopathy of undetermined significance, Waldenstrom macroglobulinemia, AL amyloidosis, and related plasma cell disorders: diagnosis and treatment. Mayo Clin Proc 2006;81:693-703.
2. Bradwell AR, Carr-Smith HD, Mead GP, Tang LX, Showell PJ, Drayson MT, Drew R. Highly sensitive automated immunoassay for immunoglobulin free light chains in serum and urine. Clin Chem 2001;47:673-80.
3. Alyanakian MA, Abbas A, Delarue R, Arnulf B, Aucouturier P. Free immunoglobulin light-chain serum levels in the follow-up of patients with monoclonal gammopathies: correlation with 24-hr urinary light-chain excretion. Am J Hematol 2004;75:246-8.
4. Singhal S, Stein R, Vickrey E, Mehta J. The serum-free light chain assay cannot replace 24-hour urine protein estimation in patients with plasma cell dyscrasias. Blood 2007;109:3611-2.
5. Dispenzieri A, Zhang L, Katzmann JA, Snyder MR, Blood E, DeGoey R, et al. Appraisal of immunoglobulin free light chain as a marker of response. Blood 2008;111:4908-15.