-
2
-
-
15944428248
-
TNF alpha inhibitors in the treatment of psoriasis and psoriatic arthritis
-
Tobin A M, Kirby B. TNF alpha inhibitors in the treatment of psoriasis and psoriatic arthritis. BioDrugs 2005: 19: 47-57.
-
(2005)
BioDrugs
, vol.19
, pp. 47-57
-
-
Tobin, A.M.1
Kirby, B.2
-
3
-
-
1842586795
-
Expression of both TNF-alpha receptor subtypes is essential for optimal skin tumour development
-
Arnott C H, Scott K A, Moore R J, Robinson S C, Thompson R G, Balkwill F R. Expression of both TNF-alpha receptor subtypes is essential for optimal skin tumour development. Oncogene 2004: 23: 1902-1910.
-
(2004)
Oncogene
, vol.23
, pp. 1902-1910
-
-
Arnott, C.H.1
Scott, K.A.2
Moore, R.J.3
Robinson, S.C.4
Thompson, R.G.5
Balkwill, F.R.6
-
4
-
-
0032983865
-
Mice deficient in tumor necrosis factor-alpha are resistant to skin carcinogenesis
-
Moore R J, Owens D M, Stamp G et al. Mice deficient in tumor necrosis factor-alpha are resistant to skin carcinogenesis. Nat Med 1999: 5: 828-831.
-
(1999)
Nat Med
, vol.5
, pp. 828-831
-
-
Moore, R.J.1
Owens, D.M.2
Stamp, G.3
-
5
-
-
0025806563
-
Murine tumor cells transduced with the gene for tumor necrosis factor-alpha. Evidence for paracrine immune effects of tumor necrosis factor against tumors
-
Asher A L, Mule J J, Kasid A et al. Murine tumor cells transduced with the gene for tumor necrosis factor-alpha. Evidence for paracrine immune effects of tumor necrosis factor against tumors. J Immunol 1991: 146: 3227-3234.
-
(1991)
J Immunol
, vol.146
, pp. 3227-3234
-
-
Asher, A.L.1
Mule, J.J.2
Kasid, A.3
-
6
-
-
27744499707
-
Skin cancer, rheumatoid arthritis, and tumor necrosis factor inhibitors
-
Chakravarty E F, Michaud K, Wolfe F. Skin cancer, rheumatoid arthritis, and tumor necrosis factor inhibitors. J Rheumatol 2005: 32: 2130-2135.
-
(2005)
J Rheumatol
, vol.32
, pp. 2130-2135
-
-
Chakravarty, E.F.1
Michaud, K.2
Wolfe, F.3
-
7
-
-
47349115562
-
TNFα impairs the S-G2/M cell cycle checkpoint and cyclobutane pyrimidine dimer repair in premalignant skin cells: Role of the PI3K-Akt pathway
-
14 February 2008; doi:
-
Faurschou A, Gniadecki R, Calay D, Wulf H C. TNFα impairs the S-G2/ M cell cycle checkpoint and cyclobutane pyrimidine dimer repair in premalignant skin cells: Role of the PI3K-Akt pathway. J Invest Dermatol 2008: 14 February 2008; doi:.
-
(2008)
J Invest Dermatol
-
-
Faurschou, A.1
Gniadecki, R.2
Calay, D.3
Wulf, H.C.4
-
8
-
-
25444466556
-
Phosphoinositide 3-kinase signaling to Akt promotes keratinocyte differentiation versus death
-
Calautti E, Li J, Saoncella S, Brissette J L, Goetinck P F. Phosphoinositide 3-kinase signaling to Akt promotes keratinocyte differentiation versus death. J Biol Chem 2005: 280: 32856-32865.
-
(2005)
J Biol Chem
, vol.280
, pp. 32856-32865
-
-
Calautti, E.1
Li, J.2
Saoncella, S.3
Brissette, J.L.4
Goetinck, P.F.5
-
9
-
-
0038624395
-
Dwarfism, impaired skin development, skeletal muscle atrophy, delayed bone development, and impeded adipogenesis in mice lacking Akt1 and Akt2
-
Peng X D, Xu P Z, Chen M L et al. Dwarfism, impaired skin development, skeletal muscle atrophy, delayed bone development, and impeded adipogenesis in mice lacking Akt1 and Akt2. Genes Dev 2003: 17: 1352-1365.
-
(2003)
Genes Dev
, vol.17
, pp. 1352-1365
-
-
Peng, X.D.1
Xu, P.Z.2
Chen, M.L.3
-
10
-
-
33644554236
-
Molecular determinants of Akt-induced keratinocyte transformation
-
Segrelles C, Moral M, Lara M F et al. Molecular determinants of Akt-induced keratinocyte transformation. Oncogene 2006: 25: 1174-1185.
-
(2006)
Oncogene
, vol.25
, pp. 1174-1185
-
-
Segrelles, C.1
Moral, M.2
Lara, M.F.3
-
11
-
-
0037309972
-
Keratinocyte-specific Pten deficiency results in epidermal hyperplasia, accelerated hair follicle morphogenesis and tumor formation
-
Suzuki A, Itami S, Ohishi M et al. Keratinocyte-specific Pten deficiency results in epidermal hyperplasia, accelerated hair follicle morphogenesis and tumor formation. Cancer Res 2003: 63: 674-681.
-
(2003)
Cancer Res
, vol.63
, pp. 674-681
-
-
Suzuki, A.1
Itami, S.2
Ohishi, M.3
-
12
-
-
27844445642
-
Perturbations of the AKT signaling pathway in human cancer
-
Altomare D A, Testa J R. Perturbations of the AKT signaling pathway in human cancer. Oncogene 2005: 24: 7455-7464.
-
(2005)
Oncogene
, vol.24
, pp. 7455-7464
-
-
Altomare, D.A.1
Testa, J.R.2
-
13
-
-
0037810249
-
Signal transduction mediated by the Ras/Raf/MEK/ERK pathway from cytokine receptors to transcription factors: Potential targeting for therapeutic intervention
-
Chang F, Steelman L S, Lee J T et al. Signal transduction mediated by the Ras/Raf/MEK/ERK pathway from cytokine receptors to transcription factors: Potential targeting for therapeutic intervention. Leukemia 2003: 17: 1263-1293.
-
(2003)
Leukemia
, vol.17
, pp. 1263-1293
-
-
Chang, F.1
Steelman, L.S.2
Lee, J.T.3
-
14
-
-
0025677334
-
Human keratinocytes are a source for tumor necrosis factor alpha: Evidence for synthesis and release upon stimulation with endotoxin or ultraviolet light
-
Kock A, Schwarz T, Kirnbauer R et al. Human keratinocytes are a source for tumor necrosis factor alpha: Evidence for synthesis and release upon stimulation with endotoxin or ultraviolet light. J Exp Med 1990: 172: 1609-1614.
-
(1990)
J Exp Med
, vol.172
, pp. 1609-1614
-
-
Kock, A.1
Schwarz, T.2
Kirnbauer, R.3
-
15
-
-
0029115193
-
Ultraviolet-B-induced apoptosis of keratinocytes: Evidence for partial involvement of tumor necrosis factor-alpha in the formation of sunburn cells
-
Schwarz A, Bhardwaj R, Aragane Y et al. Ultraviolet-B-induced apoptosis of keratinocytes: Evidence for partial involvement of tumor necrosis factor-alpha in the formation of sunburn cells. J Invest Dermatol 1995: 104: 922-927.
-
(1995)
J Invest Dermatol
, vol.104
, pp. 922-927
-
-
Schwarz, A.1
Bhardwaj, R.2
Aragane, Y.3
-
16
-
-
0029114982
-
Step-wise progression in human skin carcinogenesis in vitro involves mutational inactivation of p53, rasH oncogene activation and additional chromosome loss
-
Boukamp P, Peter W, Pascheberg U et al. Step-wise progression in human skin carcinogenesis in vitro involves mutational inactivation of p53, rasH oncogene activation and additional chromosome loss. Oncogene 1995: 11: 961-969.
-
(1995)
Oncogene
, vol.11
, pp. 961-969
-
-
Boukamp, P.1
Peter, W.2
Pascheberg, U.3
-
17
-
-
33744928116
-
Malignant transformation of immortalized HaCaT keratinocytes through deregulated nuclear factor kappaB signaling
-
Ren Q, Kari C, Quadros M R et al. Malignant transformation of immortalized HaCaT keratinocytes through deregulated nuclear factor kappaB signaling. Cancer Res 2006: 66: 5209-5215.
-
(2006)
Cancer Res
, vol.66
, pp. 5209-5215
-
-
Ren, Q.1
Kari, C.2
Quadros, M.R.3
-
18
-
-
34249781413
-
Differential p53-mediated responses to solar-simulated radiation in human papillomavirus type 16-infected keratinocytes
-
Mouret S, Favier A, Beani J C, Leccia M T. Differential p53-mediated responses to solar-simulated radiation in human papillomavirus type 16-infected keratinocytes. Exp Dermatol 2007: 16: 476-484.
-
(2007)
Exp Dermatol
, vol.16
, pp. 476-484
-
-
Mouret, S.1
Favier, A.2
Beani, J.C.3
Leccia, M.T.4
-
19
-
-
0034833977
-
Differences in activation of G2/M checkpoint in keratinocytes after genotoxic stress induced by hydrogen peroxide and ultraviolet A radiation
-
Thorn T, Gniadecki R, Petersen A B, Vicanova J, Wulf H C. Differences in activation of G2/M checkpoint in keratinocytes after genotoxic stress induced by hydrogen peroxide and ultraviolet A radiation. Free Radic Res 2001: 35: 405-416.
-
(2001)
Free Radic Res
, vol.35
, pp. 405-416
-
-
Thorn, T.1
Gniadecki, R.2
Petersen, A.B.3
Vicanova, J.4
Wulf, H.C.5
-
20
-
-
0035799557
-
Initiation of a G2/M checkpoint after ultraviolet radiation requires p38 kinase
-
Bulavin D V, Higashimoto Y, Popoff I J et al. Initiation of a G2/M checkpoint after ultraviolet radiation requires p38 kinase. Nature 2001: 411: 102-107.
-
(2001)
Nature
, vol.411
, pp. 102-107
-
-
Bulavin, D.V.1
Higashimoto, Y.2
Popoff, I.J.3
-
21
-
-
0034886729
-
Repeated exposures of human skin equivalent to low doses of ultraviolet-B radiation lead to changes in cellular functions and accumulation of cyclobutane pyrimidine dimers
-
Chouinard N, Therrien J P, Mitchell D L et al. Repeated exposures of human skin equivalent to low doses of ultraviolet-B radiation lead to changes in cellular functions and accumulation of cyclobutane pyrimidine dimers. Biochem Cell Biol 2001: 79: 507-515.
-
(2001)
Biochem Cell Biol
, vol.79
, pp. 507-515
-
-
Chouinard, N.1
Therrien, J.P.2
Mitchell, D.L.3
-
22
-
-
0035977005
-
Cyclobutane pyrimidine dimers are responsible for the vast majority of mutations induced by UVB irradiation in mammalian cells
-
You Y H, Lee D H, Yoon J H, Nakajima S, Yasui A, Pfeifer G P. Cyclobutane pyrimidine dimers are responsible for the vast majority of mutations induced by UVB irradiation in mammalian cells. J Biol Chem 2001: 276: 44688-44694.
-
(2001)
J Biol Chem
, vol.276
, pp. 44688-44694
-
-
You, Y.H.1
Lee, D.H.2
Yoon, J.H.3
Nakajima, S.4
Yasui, A.5
Pfeifer, G.P.6
-
23
-
-
33746583682
-
Concepts in molecular dermatotoxicology
-
Merk H F, Baron J M, Heise R et al. Concepts in molecular dermatotoxicology. Exp Dermatol 2006: 15: 692-704.
-
(2006)
Exp Dermatol
, vol.15
, pp. 692-704
-
-
Merk, H.F.1
Baron, J.M.2
Heise, R.3
-
24
-
-
20644446271
-
Repair of the three main types of bipyrimidine DNA photoproducts in human keratinocytes exposed to UVB and UVA radiations
-
Courdevault S, Baudouin C, Charveron M et al. Repair of the three main types of bipyrimidine DNA photoproducts in human keratinocytes exposed to UVB and UVA radiations. DNA Repair (Amst) 2005: 4: 836-844.
-
(2005)
DNA Repair (Amst)
, vol.4
, pp. 836-844
-
-
Courdevault, S.1
Baudouin, C.2
Charveron, M.3
-
25
-
-
34250788809
-
AKT/PKB signaling: Navigating downstream
-
Manning B D, Cantley L C. AKT/PKB signaling: Navigating downstream. Cell 2007: 129: 1261-1274.
-
(2007)
Cell
, vol.129
, pp. 1261-1274
-
-
Manning, B.D.1
Cantley, L.C.2
-
26
-
-
33845933899
-
The autocrine TNFalpha signalling loop in keratinocytes requires atypical PKC species and NF-kappaB activation but is independent of cholesterol-enriched membrane microdomains
-
Lisby S, Faurschou A, Gniadecki R. The autocrine TNFalpha signalling loop in keratinocytes requires atypical PKC species and NF-kappaB activation but is independent of cholesterol-enriched membrane microdomains. Biochem Pharmacol 2007: 73: 526-533.
-
(2007)
Biochem Pharmacol
, vol.73
, pp. 526-533
-
-
Lisby, S.1
Faurschou, A.2
Gniadecki, R.3
-
28
-
-
29844434429
-
In vitro sensitivity to ultraviolet B light and skin cancer risk: A case-control analysis
-
Wang L E, Xiong P, Strom S S et al. In vitro sensitivity to ultraviolet B light and skin cancer risk: A case-control analysis. J Natl Cancer Inst 2005: 97: 1822-1831.
-
(2005)
J Natl Cancer Inst
, vol.97
, pp. 1822-1831
-
-
Wang, L.E.1
Xiong, P.2
Strom, S.S.3
-
29
-
-
0028596185
-
Sunburn and p53 in the onset of skin cancer
-
Ziegler A, Jonason A S, Leffell D J et al. Sunburn and p53 in the onset of skin cancer. Nature 1994: 372: 773-776.
-
(1994)
Nature
, vol.372
, pp. 773-776
-
-
Ziegler, A.1
Jonason, A.S.2
Leffell, D.J.3
-
30
-
-
0033084012
-
TNF receptor p55 plays a pivotal role in murine keratinocyte apoptosis induced by ultraviolet B irradiation
-
Zhuang L, Wang B, Shinder G A, Shivji G M, Mak T W, Sauder D N. TNF receptor p55 plays a pivotal role in murine keratinocyte apoptosis induced by ultraviolet B irradiation. J Immunol 1999: 162: 1440-1447.
-
(1999)
J Immunol
, vol.162
, pp. 1440-1447
-
-
Zhuang, L.1
Wang, B.2
Shinder, G.A.3
Shivji, G.M.4
Mak, T.W.5
Sauder, D.N.6
-
31
-
-
14944382276
-
Infliximab induces potent anti-inflammatory responses by outside-to-inside signals through transmembrane TNF-alpha
-
Mitoma H, Horiuchi T, Hatta N et al. Infliximab induces potent anti-inflammatory responses by outside-to-inside signals through transmembrane TNF-alpha. Gastroenterology 2005: 128: 376-392.
-
(2005)
Gastroenterology
, vol.128
, pp. 376-392
-
-
Mitoma, H.1
Horiuchi, T.2
Hatta, N.3
-
32
-
-
0034754480
-
Infliximab induces apoptosis in monocytes from patients with chronic active Crohn's disease by using a caspase-dependent pathway
-
Lugering A, Schmidt M, Lugering N, Pauels H G, Domschke W, Kucharzik T. Infliximab induces apoptosis in monocytes from patients with chronic active Crohn's disease by using a caspase-dependent pathway. Gastroenterology 2001: 121: 1145-1157.
-
(2001)
Gastroenterology
, vol.121
, pp. 1145-1157
-
-
Lugering, A.1
Schmidt, M.2
Lugering, N.3
Pauels, H.G.4
Domschke, W.5
Kucharzik, T.6
-
33
-
-
0038047689
-
Infliximab but not etanercept induces apoptosis in lamina propria T-lymphocytes from patients with Crohn's disease
-
van den Brande J M, Braat H, Van Den Brink G R et al. Infliximab but not etanercept induces apoptosis in lamina propria T-lymphocytes from patients with Crohn's disease. Gastroenterology 2003: 124: 1774-1785.
-
(2003)
Gastroenterology
, vol.124
, pp. 1774-1785
-
-
van den Brande, J.M.1
Braat, H.2
Van Den Brink, G.R.3
-
34
-
-
34648814154
-
p38 MAPK in regulating cellular responses to ultraviolet radiation
-
Jinlian L, Yingbin Z, Chunbo W. p38 MAPK in regulating cellular responses to ultraviolet radiation. J Biomed Sci 2007: 14: 303-312.
-
(2007)
J Biomed Sci
, vol.14
, pp. 303-312
-
-
Jinlian, L.1
Yingbin, Z.2
Chunbo, W.3
|