Inflammatory response after phacoemulsification treated with 0.5% prednisolone acetate or vehicle

Graefe's Archive for Clinical and Experimental Ophthalmology

Volumn 246, Issue 11, 2008, Pages 1617-1622

  Lorenz, Katrin ^a   Dick, Burkhard ^a,b   Jehkul, Andreas ^c   Auffahrt, Gerd U ^d  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

^b RUHR UNIVERSITY BOCHUM   (Germany)

^c NOVARTIS PHARMA GMBH   (Germany)

^d UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Laser flare; Phacoemulsification; Prednisolone; Vehicle

Indexed keywords

EYE DROPS; PREDNISOLONE ACETATE; PREDNISOLONE PIVALATE;

ADULT; AGED; ARTICLE; CLINICAL TRIAL; CONJUNCTIVAL HYPEREMIA; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORNEA EDEMA; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; DRUG TREATMENT FAILURE; DRUG WITHDRAWAL; EYE DISCOMFORT; EYE INFLAMMATION; HUMAN; INTRAOCULAR PRESSURE; LENS IMPLANT; MAJOR CLINICAL STUDY; MULTICENTER STUDY; OPEN STUDY; PHACOEMULSIFICATION; PHASE 4 CLINICAL TRIAL; PHOTOMETRY; POSTOPERATIVE CARE; POSTOPERATIVE INFLAMMATION; PREOPERATIVE EVALUATION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; VISUAL ACUITY;

AGED; AGED, 80 AND OVER; ANTI-INFLAMMATORY AGENTS; CATARACT EXTRACTION; DOUBLE-BLIND METHOD; ENDOPHTHALMITIS; HUMANS; LASERS; LENS IMPLANTATION, INTRAOCULAR; MIDDLE AGED; OPHTHALMIC SOLUTIONS; PHACOEMULSIFICATION; PHOTOMETRY; PREDNISOLONE; VEHICLES;

EID: 54049122546     PISSN: 0721832X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00417-008-0908-2     Document Type: Article

References (26)

1. Sawa M, Sakanishi Y, Shimizu H (1984) Fluorophotometric study of anterior segment barrier functions after extracapsular cataract extraction and posterior chamber intraocular lens implantation. Am J Ophthalmol 97:197-204
2. Liesegang TJ, Bourne WM, Brubaker RF (1984) The effect of cataract surgery on the blood-aqueous barrier. Ophthalmology 91:399-402
3. Laurell CG (1998) Inflammatory response after cataract surgery. Acta Ophthalmol Scand 76(5):632-633. doi: 10.1034/j.1600-0420.1998.760512.x
4. Shah SM, Spalton DJ, Smith SE (1991) Measurement of aqueous cells and flare in normal eyes. Br J Ophthalmol 75(6):348-352. doi: 10.1136/ bjo.75.6.348
5. Laurell CG, Zetterstrom C (2002) Effects of dexamethasone, diclofenac, or placebo on the inflammatory response after cataract surgery. Br J Ophthalmol 86(12):1380-1384. doi: 10.1136/bjo.86.12.1380
6. Wenzel M, Dahlke C, Tahmaz E, Reim M (1992) Value of corticosteroids in after-care of patients after cataract extraction and lens implantation. Klin Monatsbl Augenheilkd 200(4):262-266
7. Roberts CW, Brennan KM (1995) A comparison of topical diclofenac with prednisolone for postcataract inflammation. Arch Ophthalmol 113(6):725-727
8. Shah SM, Spalton DJ, Smith SE (1991) Measurement of aqueous cells and flare in normal eyes. Br J Ophthalmol 75(6):348-352. doi: 10.1136/ bjo.75.6.348
9. Raizman M (1996) Corticosteroid therapy of eye disease. Fifty years later. Arch Ophthalmol 114:1000-1001
10. Roberts C (1996) Pretreatment with topical diclofenac sodium to decrease postoperative inflammation. Ophthalmology 103:636-639
11. Hessemer V, Schmitt K, Jacobi A (1996) Anti-inflammatory effects and aqueous humor concentration of various nonsteroidal anti-inflammatory drugs in extracapsular cataract surgery. Klin Monatsbl Augenheilkd 208(3):161-166
12. Oshika T, Yoshimura K, Miyata N (1992) Postsurgical inflammation after phacoemulsification and extracapsular extraction with soft or conventional intraocular lens implantation. J Cataract Refract Surg 18:356-361
13. Laurell CG, Zetterström C, Philipson B, Syren-Nordqvist V (1998) Randomized study of the blood-aqueous barrier reaction after phacoemulsification and extracapsular cataract extraction. Acta Ophthalmol Scand 76:573-578. doi: 10.1034/j.1600-0420.1998.760512.x
14. Pande MV, Spalton DJ, Kerr-Muir MG, Marshall J (1996) Postoperative inflammatory response to phacoemulsification and extracapsular cataract surgery: Aqueous flare and cells. J Cataract Refract Surg 22(suppl):770-774
15. Laurell CG, Wickström K, Zetterström C, Lundgren B (1997) Inflammatory response after endocapsular phacoemulsification or conventional extracapsular lens extraction in rabbit eyes. Acta Ophthalmol Scand 75:401-404
16. Wenzel M, Dahlke C, Tahmaz E, Reim M (1992) Zur Bedeutung der Kortikosteroide in der Nachsorge von Patienten nach Kataraktextraktion und Linsenimplantation. Klin Monatsbl Augenheilkd 200:262-266
17. Dick B, Kohnen T, Schmitt K, Hessemer V (1995) Lasertyndallometrie nach ECCE versus Phakoemulsifikation mit kornealer Tunnelinzision. Eine Laser-cell-flare-photometrische Untersuchung. Akt Augenheilkd 20:54-57
18. Dick B, Schwenn O, Krummenauer F, Krist R, Pfeiffer N (2000) Inflammation after sclerocorneal versus clear corneal tunnel phacoemulsification. Ophthalmology 107(2):241-247. doi: 10.1016/ S0161-6420(99)00082-2
19. Guex-Crosier Y, Pittet N, Herbort CP (1995) Sensitivity of laser flare photometry to monitor inflammation in uveitis of the posterior segment. Ophthalmology 102:613-621
20. Sawa M (1990) Clinical application of laser flare flare-cell meter. Jpn J Ophthalmol 34:346-363
21. Shah SM, Spalton DJ, Taylor JC (1992) Correlations between laser flare measurements and anterior chamber protein concentrations. Invest Ophthalmol Vis Sci 33:2878-2884
22. Powe NR, Schein OD, Gieser SC et al (1994) Synthesis of the literature on visual acuity and complications following cataract extraction with intraocular lens extraction. Arch Ophthalmol 112:239-252
23. Rossetti L, Chaudhuri J, Dickersin K (1998) Medical prophylaxis and treatment of cystoid macular edema after cataract surgery - the results of a meta-analysis. Ophthalmology 105:397-405. doi: 10.1016/ S0161-6420(98)93018-4
24. Lin CL, Wan AG, Chou JC, Shieh G, Liu JH (1994) Heparin-surface-modified intraocular lens implantation in patients with glaucoma, diabetes, or uveitis. J Cataract Refract Surg 20:550-553
25. Suresh PS, Jones NP (2001) Phacoemulsification with intraocular lens implantation in patients with uveitis. Eye 15:621-628
26. Estafanous MF, Lowder CY, Meisler DM, Chauhan R (2001) Phacoemulsification cataract extraction and posterior chamber lens implantation in patients with uveitis. Am J Ophthalmol 131:620-625. doi: 10.1016/S0002-9394(00)00909-0