Quantitative Ultrasound Characterization of Cancer Radiotherapy Effects In Vitro

International Journal of Radiation Oncology Biology Physics

Volumn 72, Issue 4, 2008, Pages 1236-1243

  Vlad, Roxana M ^a,b   Alajez, Nehad M ^a   Giles, Anoja ^b   Kolios, Michael C ^a,c   Czarnota, Gregory J ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b SUNNYBROOK RESEARCH INSTITUTE   (Canada)

^c RYERSON UNIVERSITY   (Canada)

Author keywords

Apoptosis; Mitotic arrest catastrophe; Radiotherapy; Spectral slope; Ultrasound backscatter

Indexed keywords

ACOUSTIC WAVES; BACKSCATTERING; CELL CULTURE; CELL DEATH; CYTOLOGY; DOSIMETRY; RADIOTHERAPY; TUMORS; ULTRASONIC IMAGING; ULTRASONIC TRANSMISSION; ULTRASONICS;

APOPTOSIS; ATTENUATION COEFFICIENTS; CELL LINES; CELL RESPONSES; CELL SIZES; CELLULAR RESPONSES; CONSISTENT; IMAGING MODALITIES; IN CELLS; IN VITRO; IN-VIVO; INTEGRATED BACKSCATTERS; MEASURING; MITOTIC ARREST/CATASTROPHE; MITOTIC ARRESTS; MORPHOLOGIC CHANGES; NUCLEAR; QUANTITATIVE ULTRASONIC PARAMETERS; QUANTITATIVE ULTRASOUNDS; RADIATION DOSES; SPECTRAL SLOPE; SPECTRAL SLOPES; TUMOR RESPONSES; ULTRASONIC ATTENUATIONS; ULTRASOUND BACKSCATTER; ULTRASOUND SCANNERS; VIABLE CELLS;

CELLS;

APOPTOSIS; ARTICLE; CANCER CELL; CANCER RADIOTHERAPY; CELL CYCLE ARREST; CELL SIZE; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMAGE ANALYSIS; IN VITRO STUDY; MITOSIS; PRIORITY JOURNAL; RADIATION DOSE; RADIATION SCATTERING; ULTRASOUND; ULTRASOUND SCANNER;

CELL LINE, TUMOR; CELL PROLIFERATION; CELL SIZE; CELL SURVIVAL; HUMANS; NEOPLASMS;

EID: 54049121530     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2008.07.027     Document Type: Article

References (31)

1. Weber W.A., and Figlin R. Monitoring cancer treatment with PET/CT: Does it make a difference?. J Nucl Med 48 (2007) 36S-44S
2. Erasmus J.J., and Munden R.F. The role of integrated computed tomography positron-emission tomography in esophageal cancer: Staging and assessment of therapeutic response. Semin Radiat Oncol 17 (2007) 29-37
3. Brasch R.C., Li K.C., Husband J.E., et al. In vivo monitoring of tumor angiogenesis with MR imaging. Acad Radiol 7 (2000) 812-823
4. Preda A., Wielopolski P.A., Ten Hagen T.L., et al. Dynamic contrast-enhanced MRI using macromolecular contrast media for monitoring the response to isolated limb perfusion in experimental soft-tissue sarcomas. MAGMA 17 (2004) 296-302
5. Lassau N., Lamuraglia M., Vanel D., et al. Doppler US with perfusion software and contrast medium injection in the early evaluation of isolated limb perfusion of limb sarcomas: Prospective study of 49 cases. Ann Oncol 16 (2005) 1054-1060
6. Lizzi F.L., Feleppa E.J., Kaisar A.S., et al. Ultrasonic spectrum analysis for tissue evaluation. Pattern Recognition Letters 24 (2003) 637-658
7. Lizzi F.L., King D.L., Rorke M.C., et al. Comparison of theoretical scattering results and ultrasonic data from clinical liver examinations. Ultrasound Med Biol 14 (1988) 377-385
8. Yang M., Krueger T.M., Miller J.G., et al. Characterization of anisotropic myocardial backscatter using spectral slope, intercept and midband fit parameters. Ultrason Imaging 29 (2007) 122-134
9. Oelze M.L., O'Brien Jr. W.D., Blue J.P., et al. Differentiation and characterization of rat mammary fibroadenomas and 4T1 mouse carcinomas using quantitative ultrasound imaging. IEEE Trans Med Imaging 23 (2004) 764-771
10. Feleppa E.J., Kalisz A., Melgar S., et al. Typing of prostate tissue by ultrasonic spectrum analysis. IEEE Trans Ultrason Ferroelectr Freq Control 43 (1996) 609-619
11. Balaji K.C., Fair W.R., Feleppa E.J., et al. Role of advanced 2 and 3-dimensional ultrasound for detecting prostate cancer. J Urol 168 (2002) 2422-2425
12. Tannock I.F., Hill R.P., Bristow R.G., et al. The basic science of oncology. 4th ed. (2005), McGraw-Hill, New York
13. Czarnota G.J., Kolios M.C., Abraham J., et al. Ultrasound imaging of apoptosis: High-resolution non-invasive monitoring of programmed cell death in vitro, in situ and. in vivo. Br J Cancer 81 (1999) 520-527
14. Kolios M.C., Czarnota G.J., Lee M., et al. Ultrasonic spectral parameter characterization of apoptosis. Ultrasound Med Biol 28 (2002) 589-597
15. Kolios M.C., and Czarnota G.J. New insights into high frequency ultrasonic tissue scattering. [Abstract]. In the 11th International Symposium on Advanced Biomedical Ultrasound, Sendai, Japan (2008)
16. Wang C., Koistinen P., Yang G.S., et al. Mast cell growth factor, a ligand for the receptor encoded by c-kit, affects the growth in culture of the blast cells of acute myeloblastic leukemia. Leukemia 5 (1991) 493-499
17. Taggart L.R., Baddour R.E., Giles A., et al. Ultrasonic characterization of whole cells and isolated nuclei. Ultrasound Med Biol 33 (2007) 389-401
18. Lizzi F.L., Astor M., Feleppa E.J., et al. Statistical framework for ultrasonic spectral parameter imaging. Ultrasound Med Biol 23 (1997) 1371-1382
19. Lizzi F.L., Greenebaum M., Feleppa E.J., et al. Theoretical framework for spectrum analysis in ultrasonic tissue characterization. J Acoust Soc Am 73 (1983) 1366-1373
20. Crocker M.J. Encyclopedia of acoustics (1997), Wiley, New York
21. Pozarowski P., Grabarek J., and Darzynkiewicz Z. Flow cytometry of apoptosis. Curr Protoc Cell Biol (2004) Chapter 18:Unit 18.8
22. Lizzi F.L., Ostromogilsky M., Feleppa E.J., et al. Relationship of ultrasonic spectral parameters to features of tissue microstructure. IEEE Trans Ultrason Ferroelectr Freq Control 34 (1987) 319-329
23. Darzynkiewicz Z., Juan G., Li X., et al. Cytometry in cell necrobiology: Analysis of apoptosis and accidental cell death (necrosis). Cytometry 27 (1997) 1-20
24. Hunt J.W., Worthington A.E., and Kerr A.T. The subtleties of ultrasound images of an ensemble of cells: Simulation from regular and more random distributions of scatterers. Ultrasound Med Biol 21 (1995) 329-341
25. Hunt J.W., Worthington A.E., Xuan A., et al. A model based upon pseudo regular spacing of cells combined with the randomisation of the nuclei can explain the significant changes in high-frequency ultrasound signals during apoptosis. Ultrasound Med Biol 28 (2002) 217-226
26. Vlad R.M., Brand S., Giles A., et al. Quantitative ultrasound assessing tumor responses to radiotherapy in cancer mouse models. [Abstract]. Ultrasonic Imaging 29 (2008) 255-256
27. Vlad R.M., Czarnota G.J., Giles A., et al. High-frequency ultrasound for monitoring changes in liver tissue during preservation. Phys Med Biol 50 (2005) 197-213
28. Vlad R.M., Orlova V., Hunt J.W., et al. Changes measured in the backscatter ultrasound signals during cell death can be potentially explained by an increase in cell size variance. [Abstract]. Ultrasonic Imaging 29 (2008) 256
29. Ursea R., Coleman D.J., Silverman R.H., et al. Correlation of high-frequency ultrasound backscatter with tumor microstructure in iris melanoma. Ophthalmology 105 (1998) 906-912
30. Lizzi F.L. Ultrasonic scatterer-property images of the eye and prostate. IEEE Ultrasonics Symposium Proceedings 2 (1997) 1109-1118
31. Lightdale C.J., and Kulkarni K.G. Role of endoscopic ultrasonography in the staging and follow-up of esophageal cancer. J Clin Oncol 23 (2005) 4483-4489