Separation, synthesis and estrogenic activity of 4-nonylphenols: Two sets of new diastereomeric isomers in a commercial mixture

Chemosphere

Volumn 73, Issue 8, 2008, Pages 1188-1193

  Makino, Mitsuko ^a   Uchiyama, Taketo ^a   Saito, Hiroaki ^a   Ogawa, Shoujiro ^a   Iida, Takashi ^a   Katase, Takao ^a   Fujimoto, Yasuo ^a  

^a NIHON UNIVERSITY   (Japan)

Author keywords

Diastereomeric nonylphenol isomers; HPLC separation; Nonylphenol synthesis; Stereostructure estrogenic activity relationship

Indexed keywords

BENZENE; CHEMICAL REACTIONS; FRIEDEL-CRAFTS REACTION; HYDROCARBONS; ISOMERS; MIXTURES; PHENOLS; SEPARATION;

BENZENE RING; COMMERCIAL MIXTURES; DIASTEREOMER; DIASTEREOMERIC; DIASTEREOMERIC NONYLPHENOL ISOMERS; DIASTEREOMERS; ESTROGENIC ACTIVITIES; HEPTANOL; HPLC SEPARATION; HYPERCARB; METHYL GROUPS; NONYLPHENOL; NONYLPHENOL SYNTHESIS; NONYLPHENOLS; PROTON SIGNALS; STEREOSTRUCTURE; STEREOSTRUCTURE-ESTROGENIC ACTIVITY RELATIONSHIP;

NUCLEAR PROPULSION;

4 (3,4 DIMETHYLHEPTAN 3 YL)PHENOL; 4 (3,4 DIMETHYLHEPTAN 4 YL)PHENOL; 4 (3,5 DIMETHYLHEPTAN 3 YL)PHENOL; 4 NONYLPHENOL; PHENOL DERIVATIVE; UNCLASSIFIED DRUG;

ESTROGENIC COMPOUND; PHENOLIC COMPOUND; SEPARATION;

ARTICLE; CHEMICAL STRUCTURE; DIASTEREOISOMER; ESTROGEN ACTIVITY; MOLECULAR RECOGNITION; STRUCTURE ANALYSIS; SYNTHESIS;

COMPLEX MIXTURES; ESTROGENS; HUMANS; PHENOLS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 54049119166     PISSN: 00456535     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chemosphere.2008.07.075     Document Type: Article

References (13)

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