Evoking blinks with natural stimulation and detecting them with a noninvasive optical device: A simple, inexpensive method for use with freely moving animals

Journal of Neuroscience Methods

Volumn 173, Issue 1, 2008, Pages 108-113

  Weiss, Craig ^a   Disterhoft, John F ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Blink; Conditioning; Infrared detector; Optical sensor; Periorbital; Reflex modification; Tether; Unconditioned response

Indexed keywords

ARTICLE; BIOSENSOR; ELECTROMYOGRAPHY; EVOKED VISUAL RESPONSE; EYELID REFLEX; GENETIC MANIPULATION; IMPLANTATION; NONHUMAN; POLARIMETRY; PRIORITY JOURNAL; REFLEX; STIMULATION;

EID: 54049112984     PISSN: 01650270     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneumeth.2008.05.027     Document Type: Article

References (25)

1. Bangasser DA, Shors TJ. The hippocampus is necessary for enhancements and impairments of learning following stress. Nat Neurosci 2007;10(11):1401-3.
2. Cartford MC, Gemma C, Bickford PC. Eighteen-month-old Fischer 344 rats fed a spinach-enriched diet show improved delay classical eyeblink conditioning and reduced expression of tumor necrosis factor alpha (TNFalpha) and TNFbeta in the cerebellum. J Neurosci 2002;22(14):5813-6.
3. Cartford MC, Samec A, Fister M, Bickford PC. Cerebellar norepinephrine modulates learning of delay classical eyeblink conditioning: evidence for post-synaptic signaling via PKA. Learn Memory 2004;11(6):732-7.
4. Dauvergne C, Evinger C. Experiential modification of the trigeminal reflex blink circuit. J Neurosci 2007;27(39):10414-22.
5. Evinger C, Manning KA. A model system for motor learning: adaptive gain control of the blink reflex. Exp. Brain Res 1988;70(3):527-38.
6. Freeman JH, Halverson HE, Hubbard EM. Inferior colliculus lesions impair eyeblink conditioning in rats. Learn Memory 2007;14(12):842-6.
7. Gormezano I, Schneiderman N, Deaux E, Fuentes I. Nictitating membrane: classical conditioning and extinction in the albino rabbit. Science 1962;138:33-4.
8. Koekkoek SK, Den Ouden WL, Perry G, Highstein SM, De Zeeuw CI. Monitoring kinetic and frequency-domain properties of eyelid responses in mice with magnetic distance measurement technique. J Neurophysiol 2002;88(4):2124-33.
9. Kronforst-Collins MA, Weiss C, Disterhoft JF. Sensitization of the eyeblink response in the restrained mouse. Soc Neurosci Abs 1996;22:1647.
10. Kuo AG, Lee G, Disterhoft JF. Simultaneous training on two hippocampus-dependent tasks facilitates acquisition of trace eyeblink conditioning. Learn Memory 2006;13(2):201-7.
11. Moskal R, Kuo AG, Weiss C, Wood P, O'Connor-Hanson A, Kelso S, et al. GLYX-13: a monoclonal antibody-derived peptide that act as an N-methyl-D-aspartate receptor modulator. Neuropharmacology 2005;49(7):1077-87.
12. Schmajuk N, Christiansen BA. Eyeblink conditioning in rats. Physiol Behav 1990;48:755-8.
13. Schreurs BG, Oh MM, Hirashima C, Alkon DL. Conditioning-specific modification of the rabbit's unconditioned nictitating membrane response. Behav Neurosci 1995;109(1):24-33.
14. Servatius RJ. Eyeblink conditioning in the freely moving rat: square-wave stimulation as the unconditioned stimulus. J Neurosci Methods 2000;102(1):35-42.
15. Skelton RW. Bilateral cerebellar lesions disrupt conditioned eyelid response in unrestrained rats. Behav Neurosci 1988;102:586-90.
16. Stanton ME, Peloso E, Brown KL, Rodier P. Discrimination learning and reversal of the conditioned eyeblink reflex in a rodent model of autism. Behav Brain Res 2007;176(1):133-40.
17. Takatsuki K, Kawahara S, Takehara K, Kishimoto Y, Kirino Y. Effects of the noncompetitive NMDA receptor antagonist MK-801 on classical eyeblink conditioning in mice. Neuropharmacology 2001;41(5):618-28.
18. Takehara-Nishiuchi K, Nakao K, Kawahara S, Matsuki N, Kirino Y. Systems consolidation requires postlearning activation of NMDA receptors in the medial prefrontal cortex in trace eyeblink conditioning. J Neurosci 2006;26(19):5049-58.
19. Thompson LT, Moyer Jr JR, Akase E, Disterhoft JF. A systemfor quantitative analysis of associative learning. Part 1. Hardware interfaces with cross-species applications. J Neurosci Methods 1994;54(1):109-17.
20. Weiss C, Bouwmeester H, Power JM, Disterhoft JF. Hippocampal lesions prevent trace eyeblink conditioning in the freely moving rat. Behav Brain Res 1999a;99(2):123-32.
21. Weiss C, Knuttinen M-G, Power JM, Patel RI, O'Connor MS, Disterhoft JF. Trace eyeblink conditioning in the freely moving rat: optimizing the conditioning parameters. Behav Neurosci 1999b;113(5):1-6.
22. Weiss C, Kronforst-Collins MA, Disterhoft JF. Eyeblink conditioning in the freely moving mouse. Soc Neurosci Abs 1996;22:1648.
23. Weiss C, Lindemuller S, Pak E, Disterhoft JF. Eyeblink conditioning in the freely moving mouse: auditory vs. visual CSs. Soc Neurosci Abs 1997;23:783.
24. Weiss C, Venkatasubramanian PN, Aguado AS, Power JM, Tom BC, Li L, et al. Impaired eyeblink conditioning and decreased hippocampal volume in PDAPPV717F mice. Neurobiol Dis 2002;11:425-33.
25. Weisz DJ, LoTurco JJ. Reflex facilitation of the nictitating membrane response remains after cerebellar lesions. Behav Neurosci 1988;102(2):203-9.