메뉴 건너뛰기




Volumn 22, Issue 4, 2008, Pages 497-505

Evaluation of apoptotic cells and immunohistochemical detection of FAS, FAS-L, Bcl-2, Bax, p52 and c-Myc in the skin of patients with chronic venous leg ulcers

Author keywords

Apoptosis; Immunohistochemistry; Leg ulcer; Skin; Venous disease

Indexed keywords

FAS ANTIGEN; FAS LIGAND; MYC PROTEIN; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53;

EID: 54049110382     PISSN: 11073756     EISSN: None     Source Type: Journal    
DOI: 10.3892/ijmm_00000048     Document Type: Article
Times cited : (5)

References (34)
  • 1
    • 0034100218 scopus 로고    scopus 로고
    • Expression and localization of p53 and bcl-2 in healing wounds in diabetic and non-diabetic mice
    • Kane CD and Greenhalgh DG: Expression and localization of p53 and bcl-2 in healing wounds in diabetic and non-diabetic mice. Wound Repair Regen 8: 45-58, 2000.
    • (2000) Wound Repair Regen , vol.8 , pp. 45-58
    • Kane, C.D.1    Greenhalgh, D.G.2
  • 2
    • 0041326643 scopus 로고    scopus 로고
    • Expression of apoptosis- and cell cycle-related proteins in epidermis of venous leg and diabetic foot ulcers
    • Galkowska H, Olszewsk WL, Wojewodzka U, et al: Expression of apoptosis- and cell cycle-related proteins in epidermis of venous leg and diabetic foot ulcers. Surgery 134: 213-220, 2003.
    • (2003) Surgery , vol.134 , pp. 213-220
    • Galkowska, H.1    Olszewsk, W.L.2    Wojewodzka, U.3
  • 3
    • 26044483530 scopus 로고    scopus 로고
    • Apoptosis: A basic physiologic process in wound healing
    • Rai NK, Tripathi K, Sharma D, et al: Apoptosis: a basic physiologic process in wound healing. Int J Low Extrem. Wounds 4: 138-144, 2005.
    • (2005) Int J Low Extrem. Wounds , vol.4 , pp. 138-144
    • Rai, N.K.1    Tripathi, K.2    Sharma, D.3
  • 4
    • 9744220377 scopus 로고    scopus 로고
    • Venous leg ulcers and apoptosis: A TIMP-3 mediated pathway?
    • Heroy Y, Kahle B, Idzko M, et al: Venous leg ulcers and apoptosis: a TIMP-3 mediated pathway? J Invest Dermatol 123: 1210-1212, 2004.
    • (2004) J Invest Dermatol , vol.123 , pp. 1210-1212
    • Heroy, Y.1    Kahle, B.2    Idzko, M.3
  • 5
    • 0029615515 scopus 로고
    • Epidermal proliferation is not impaired in chronic venous ulcers
    • Andriessen MP, van Bergen BH, Spruijt KI, et al: Epidermal proliferation is not impaired in chronic venous ulcers. Acta Derm Venereol 75: 459-462, 1995.
    • (1995) Acta Derm Venereol , vol.75 , pp. 459-462
    • Andriessen, M.P.1    van Bergen, B.H.2    Spruijt, K.I.3
  • 6
    • 0037352102 scopus 로고    scopus 로고
    • Bonner Venenstudie der Deutschen Gesellschaft fOr Phlebologie. Epidemiologische Untersuchung zur Frage der Häufigkeit und Ausprägung von chronischen Venenkrankheiten in der städtischen und läindlichen Wohnbevölkerang.
    • Rabe E, Pannier-Fischer F, Bromen K, et al: Bonner Venenstudie der Deutschen Gesellschaft fOr Phlebologie. Epidemiologische Untersuchung zur Frage der Häufigkeit und Ausprägung von chronischen Venenkrankheiten in der städtischen und läindlichen Wohnbevölkerang. Phlebologie 32: 1-14, 2003.
    • (2003) Phlebologie , vol.32 , pp. 1-14
    • Rabe, E.1    Pannier-Fischer, F.2    Bromen, K.3
  • 7
    • 33747147127 scopus 로고    scopus 로고
    • A review of the microcirculation in skin in patients with chronic venous insufficiency: The problem and the evidence available for therapeutic options
    • Wollina U, Abdel-Naser MB and Mani R: A review of the microcirculation in skin in patients with chronic venous insufficiency: the problem and the evidence available for therapeutic options. Int J Lower Extremety Wounds 5: 169-180, 2006.
    • (2006) Int J Lower Extremety Wounds , vol.5 , pp. 169-180
    • Wollina, U.1    Abdel-Naser, M.B.2    Mani, R.3
  • 8
    • 0141612813 scopus 로고    scopus 로고
    • Disturbed vasomotion in chronic venous insufficiency
    • Stücker M, Steinbrügge J, Memmel U, et al: Disturbed vasomotion in chronic venous insufficiency. J Vasc Surg 38: 522-527, 2003.
    • (2003) J Vasc Surg , vol.38 , pp. 522-527
    • Stücker, M.1    Steinbrügge, J.2    Memmel, U.3
  • 9
    • 0034566561 scopus 로고    scopus 로고
    • Microcirculatory dysfunction in chronic venous insufficiency
    • Jünger M, Steins A, Hahn M, et al: Microcirculatory dysfunction in chronic venous insufficiency. Microcirculation 7: S3-S12, 2000.
    • (2000) Microcirculation , vol.7
    • Jünger, M.1    Steins, A.2    Hahn, M.3
  • 10
    • 0041568189 scopus 로고    scopus 로고
    • The role of apoptosis in human epidermal keratinocytes
    • Weisfelner ME and Gottlieb AB: The role of apoptosis in human epidermal keratinocytes. J Drugs Dermatol 4: 385-391, 2003.
    • (2003) J Drugs Dermatol , vol.4 , pp. 385-391
    • Weisfelner, M.E.1    Gottlieb, A.B.2
  • 11
    • 0027281682 scopus 로고
    • Cell death by apoptosis in epidermal biology
    • Haake AR and Polakowska RR: Cell death by apoptosis in epidermal biology. J Invest Dermatol 101: 107-112, 1993.
    • (1993) J Invest Dermatol , vol.101 , pp. 107-112
    • Haake, A.R.1    Polakowska, R.R.2
  • 12
  • 14
    • 0031817363 scopus 로고    scopus 로고
    • Expression of the bcl-2 homologue bax in normal human skin, psoriasis vulgaris and non-melanoma skin cancers
    • Tomkova H, Fujimoto W and Arata J: Expression of the bcl-2 homologue bax in normal human skin, psoriasis vulgaris and non-melanoma skin cancers. Eur J Dermatol 8: 256-260, 1998.
    • (1998) Eur J Dermatol , vol.8 , pp. 256-260
    • Tomkova, H.1    Fujimoto, W.2    Arata, J.3
  • 15
    • 0036087028 scopus 로고    scopus 로고
    • Role of Bcl-2 family of proteins in malignancy
    • Baliga BC and Kumar S: Role of Bcl-2 family of proteins in malignancy. Hematol Oncol 20: 63-74, 2002.
    • (2002) Hematol Oncol , vol.20 , pp. 63-74
    • Baliga, B.C.1    Kumar, S.2
  • 16
    • 0030778620 scopus 로고    scopus 로고
    • c-Myc promotes differentiation of human epidermal stem cells
    • Gandarillas A and Watt FM: c-Myc promotes differentiation of human epidermal stem cells. Genes Dev 11: 2869-2882, 1997.
    • (1997) Genes Dev , vol.11 , pp. 2869-2882
    • Gandarillas, A.1    Watt, F.M.2
  • 17
    • 0033607029 scopus 로고    scopus 로고
    • Targeted expression of c-Myc in the epidermis alters normal proliferation, differentiation and UV-B induced apoptosis
    • Waikel RL, Wang XJ and Roop DR: Targeted expression of c-Myc in the epidermis alters normal proliferation, differentiation and UV-B induced apoptosis. Oncogene 18: 4870-4878, 1999.
    • (1999) Oncogene , vol.18 , pp. 4870-4878
    • Waikel, R.L.1    Wang, X.J.2    Roop, D.R.3
  • 18
    • 0028827225 scopus 로고
    • Plasminogen activators, venous leg ulcers and reepithelialization
    • Lotti T and Benci M: Plasminogen activators, venous leg ulcers and reepithelialization. Int J Dermatol 34: 696-699, 1995.
    • (1995) Int J Dermatol , vol.34 , pp. 696-699
    • Lotti, T.1    Benci, M.2
  • 19
    • 0029981845 scopus 로고    scopus 로고
    • Diagnosis of venous disease of the lower leg extremeties: The CEAP classification
    • Kistner RL, Eklof B and Masuda EM: Diagnosis of venous disease of the lower leg extremeties: the CEAP classification. Mayo Clin Proc 71: 338-345, 1996.
    • (1996) Mayo Clin Proc , vol.71 , pp. 338-345
    • Kistner, R.L.1    Eklof, B.2    Masuda, E.M.3
  • 20
    • 0029950445 scopus 로고    scopus 로고
    • Influence of healing on the disturbed blood flow regulation in venous ulcers
    • Jünger M, Hahn M, Klyscz T, et al: Influence of healing on the disturbed blood flow regulation in venous ulcers. VASA 25: 341-348, 1996.
    • (1996) VASA , vol.25 , pp. 341-348
    • Jünger, M.1    Hahn, M.2    Klyscz, T.3
  • 21
    • 0030228923 scopus 로고    scopus 로고
    • Disturbed blood flow regulation in venous leg ulcers
    • Jünger M, Klyscz T, Hahn M, et al: Disturbed blood flow regulation in venous leg ulcers. Int J Microcirc 16: 259-265, 1996.
    • (1996) Int J Microcirc , vol.16 , pp. 259-265
    • Jünger, M.1    Klyscz, T.2    Hahn, M.3
  • 22
    • 0031021529 scopus 로고    scopus 로고
    • Microvascular changes in venous disease: An update
    • Bollinger A, Leu AJ, Hoffmann U, et al: Microvascular changes in venous disease: an update. Angiology 48: 27-32, 1997.
    • (1997) Angiology , vol.48 , pp. 27-32
    • Bollinger, A.1    Leu, A.J.2    Hoffmann, U.3
  • 23
    • 0030781073 scopus 로고    scopus 로고
    • Cutaneous inflammation limited to the region of the ulcer in chronic venous insufficiency
    • Hahn J, Jünger M, Friedrich B, et al: Cutaneous inflammation limited to the region of the ulcer in chronic venous insufficiency. VASA 26: 277-281, 1997.
    • (1997) VASA , vol.26 , pp. 277-281
    • Hahn, J.1    Jünger, M.2    Friedrich, B.3
  • 24
    • 0030932427 scopus 로고    scopus 로고
    • Tissue oxygenation and microcirculation in dermatoliposclerosis with different degrees of erythema at the margins of venous ulcers. A contribution to hypodermitis symptoms
    • Schmeller W, Roszinski S and Huesmann M: Tissue oxygenation and microcirculation in dermatoliposclerosis with different degrees of erythema at the margins of venous ulcers. A contribution to hypodermitis symptoms. VASA 26: 18-24, 1997.
    • (1997) VASA , vol.26 , pp. 18-24
    • Schmeller, W.1    Roszinski, S.2    Huesmann, M.3
  • 25
    • 0026098434 scopus 로고
    • Immunohistochemical investigation of dermal capillaries in chronic venous insufficiency
    • Vanscheidt W, Laaff H, Weiss JM, et al: Immunohistochemical investigation of dermal capillaries in chronic venous insufficiency. Acta Derm Venereol 71: 17-19, 1991.
    • (1991) Acta Derm Venereol , vol.71 , pp. 17-19
    • Vanscheidt, W.1    Laaff, H.2    Weiss, J.M.3
  • 26
    • 0028352657 scopus 로고
    • Transcutaneous Po2 and Pco2 measurement in dermatology
    • Takiwaki H: Transcutaneous Po2 and Pco2 measurement in dermatology. Acta Derm Venereol Suppl. 185: 21-25, 1994.
    • (1994) Acta Derm Venereol Suppl , vol.185 , pp. 21-25
    • Takiwaki, H.1
  • 27
    • 0034253778 scopus 로고    scopus 로고
    • Pericapillary fibrin deposits and skin hypoxia precede the changes of lipodermatosclerosis in limbs at increased risk of developing a venous ulcer
    • Stacey MC, Burnand KG, Bhogal BS, et al: Pericapillary fibrin deposits and skin hypoxia precede the changes of lipodermatosclerosis in limbs at increased risk of developing a venous ulcer. Cardiovasc Surg 8: 372-380, 2000.
    • (2000) Cardiovasc Surg , vol.8 , pp. 372-380
    • Stacey, M.C.1    Burnand, K.G.2    Bhogal, B.S.3
  • 29
    • 1242320230 scopus 로고    scopus 로고
    • Ageing of human epidermis. the role of apoptosis, Fas and telomerase
    • Gilhar A, Ullmann Y, Karry R, et al: Ageing of human epidermis. the role of apoptosis, Fas and telomerase. Br J Dermatol 150: 56-63, 2004.
    • (2004) Br J Dermatol , vol.150 , pp. 56-63
    • Gilhar, A.1    Ullmann, Y.2    Karry, R.3
  • 30
    • 7444224713 scopus 로고    scopus 로고
    • Analysis of p53 and bcl-2 protein expression in the non-tumorigenic, pretumorigenic, and tumorigenic keratinocytic hyperproliferative lesions
    • Hussein MR, Al-Badaiwy ZH and Guirguis MN: Analysis of p53 and bcl-2 protein expression in the non-tumorigenic, pretumorigenic, and tumorigenic keratinocytic hyperproliferative lesions. J Cutan Pathol 31: 643-651, 2004.
    • (2004) J Cutan Pathol , vol.31 , pp. 643-651
    • Hussein, M.R.1    Al-Badaiwy, Z.H.2    Guirguis, M.N.3
  • 32
    • 0034051626 scopus 로고    scopus 로고
    • Immunohistochemical study on fas and fas-ligand in skin wound healing
    • Guan DW, Ohshima T and Kondo T: Immunohistochemical study on fas and fas-ligand in skin wound healing. Histochem J 32: 85-91, 2000.
    • (2000) Histochem J , vol.32 , pp. 85-91
    • Guan, D.W.1    Ohshima, T.2    Kondo, T.3
  • 33
    • 33744802411 scopus 로고    scopus 로고
    • Apoptosis in physiological and pathological skin: Implications for therapy
    • Boehm I: Apoptosis in physiological and pathological skin: implications for therapy. Curr Mol Med 6: 375-341, 2006.
    • (2006) Curr Mol Med , vol.6 , pp. 375-341
    • Boehm, I.1
  • 34
    • 34447120704 scopus 로고    scopus 로고
    • Expression of Bcl-2 family proteins in psoriasis
    • Batinac T, Zamolo G. Hadzisejdic I, et al: Expression of Bcl-2 family proteins in psoriasis. Croat Med J 48: 319-326, 2007.
    • (2007) Croat Med J , vol.48 , pp. 319-326
    • Batinac, T.1    Zamolo, G.2    Hadzisejdic, I.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.