Differential expression of metallothionein (MT) gene by trace metals and endocrine-disrupting chemicals in the hermaphroditic mangrove killifish, Kryptolebias marmoratus

Ecotoxicology and Environmental Safety

Volumn 72, Issue 1, 2009, Pages 206-212

  Rhee, Jae Sung ^a   Raisuddin, Sheikh ^a   Hwang, Dae Sik ^a   Lee, Kyun Woo ^a   Kim, Il Chan ^b   Lee, Jae Seong ^a  

^a Hanyang University   (South Korea)

^b Korea Research Institute of Ships and Ocean Engineering   (South Korea)

Author keywords

Biomarker; Chemical interaction; Confounding factors; Endocrine disrupting chemicals; Kryptolebias marmoratus; Metal pollution; Metallothionein; Tissue distribution

Indexed keywords

BIOLOGICAL MARKER; CADMIUM; COPPER; ENDOCRINE DISRUPTOR; METALLOTHIONEIN; TRACE METAL; ZINC;

BIOMARKER; BRAIN; CYPRINID; DEVELOPMENTAL STAGE; ENDOCRINE DISRUPTOR; GENE EXPRESSION; HERMAPHRODITE; MANGROVE; METALLOTHIONEIN; ORGANIC POLLUTANT; POLLUTION EFFECT; POLLUTION EXPOSURE; TIME SERIES ANALYSIS; TRACE METAL;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DEVELOPMENTAL STAGE; ENVIRONMENTAL EXPOSURE; FISH; GENE; GENE EXPRESSION; GENE INDUCTION; GENE REPRESSION; HERMAPHRODITISM; MANGROVE KILLFISH; MT GENE; NONHUMAN; NUCLEOTIDE SEQUENCE;

ANIMALS; BRAIN; BREEDING; CADMIUM; COPPER; CYPRINIDAE; EYE; FUNDULIDAE; GENE EXPRESSION REGULATION; HERMAPHRODITISM; LIVER; METALLOTHIONEIN; MUSCLE, SKELETAL; ORGAN SPECIFICITY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SKIN; TRACE ELEMENTS; ZINC;

CYPRINODONTOIDEI; KRYPTOLEBIAS MARMORATUS;

EID: 54049109943     PISSN: 01476513     EISSN: 10902414     Source Type: Journal    
DOI: 10.1016/j.ecoenv.2008.06.001     Document Type: Article

References (42)

1. Amiard J.C., Amiard-Triquet C., Barka S., Pellerin J., and Rainbow P.S. Metallothioneins in aquatic invertebrates: their role in metal detoxification and their use as biomarkers. Aquat. Toxicol. 76 (2006) 160-202
2. Andrews G.K. Regulation of metallothionein gene expression by oxidative stress and metal ions. Biochem. Pharmacol. 59 (2000) 95-104
3. Atif F., Kaur M., Yousuf S., and Raisuddin S. In vitro free radical scavenging activity of hepatic metallothionein induced in an Indian freshwater fish, Channa punctata Bloch. Chem.-Biol. Interact. 162 (2006) 172-180
4. Canesi L., Borghi C., Ciacci C., Fabbri R., Vergani L., and Gallo G. Bisphenol-A alters gene expression and functional parameters in molluscan hepatopancreas. Mol. Cell. Endocrinol. 276 (2007) 36-44
5. Chen W.Y., John J.A., Lin C.H., Lin H.F., Wu S.C., Lin C.H., and Chang C.Y. Expression of metallothionein gene during embryonic and early larval development in zebrafish. Aquat. Toxicol. 69 (2004) 215-227
6. Choi C.Y., An K.W., Nelson E.R., and Habibi H.R. Cadmium affects the expression of metallothionein (MT) and glutathione peroxidase (GPX) mRNA in goldfish, Carassius auratus. Comp. Biochem. Physiol. 145C (2007) 595-600
7. Costa, P.M., Repolho, T., Caeiro, S., Diniz, M.E., Moura, I., Costa, M.H., 2007. Modelling metallothionein induction in the liver of Sparus aurata exposed to metal-contaminated sediments. Ecotoxicol. Environ. Saf., in press, doi:10.1016/j.ecoenv.2007.05.012.
8. Coyle P., Philcox J.C., Carey L.C., and Rofe A.M. Metallothionein: the multipurpose protein. Cell. Mol. Life Sci. 59 (2002) 627-647
9. Durnam D.M., and Palmiter R.D. Transcriptional regulation of the mouse metallothionein-I gene by heavy metals. J. Biol. Chem. 256 (1981) 5712-5716
10. George S., Gubbins M., MacIntosh A., Reynolds W., Sabine V., Scott A., and Thain J. A comparison of pollutant biomarker responses with transcriptional responses in European flounders (Platicthys flesus) subjected to estuarine pollution. Mar. Environ. Res. 58 (2004) 571-575
11. Gerpe M., Kling P., Berg A.H., and Olsson P.E. Arctic char (Salvelinus alpinus) metallothionein: cDNA sequence, expression, and tissue-specific inhibition of cadmium-mediated metallothionein induction by 17β-estradiol, 4-OH-PCB 30, and PCB 104. Envrion. Toxicol. Chem. 19 (2000) 638-645
12. Gonzalez P., Baudrimont M., Boudou A., and Bourdineaud J.P. Comparative effects of direct cadmium contamination on gene expression in gills, liver, skeletal muscles and brain of the zebrafish (Danio rerio). Biometals 19 (2006) 225-235
13. Kägi J.H., Vasák M., Lerch K., Gilg D.E., Hunziker P., Bernhard W.R., and Good M. Structure of mammalian metallothionein. Environ. Health Perspect. 54 (1984) 93-103
14. Kim I.-C., Kim Y.-J., Yoon Y.-D., Kawamura S., Lee Y.-S., and Lee J.-S. Cloning of cytochrome P450 1A (CYP1A) genes from the hermaphrodite fish Rivulus marmoratus and the Japanese medaka Oryzias latipes. Mar. Environ. Res. 58 (2004) 125-129
15. Kim J.-H., Wang S.-Y., Raisuddin S., Lee J.-S., and Han K.-N. Cloning of a river pufferfish (Takifugu obscurus) metallothionein cDNA and study of its induction profile in cadmium-exposed fish. Chemosphere 71 (2008) 1251-1259
16. Klaassen C.D., Liu J., and Choudhuri S. Metallothionein: an intracellular protein to protect against cadmium toxicity. Annu. Rev. Pharmacol. Toxicol. 39 (1999) 267-294
17. Lee J.-S. Genomic cloning of a heat shock cognate 71-1 gene (HSC71-1) from the hermaphroditic fish Rivulus marmoratus (Cyprinodontiformes, Rivulidae). DNA Seq. 15 (2004) 33-38
18. Lee Y.-M., Williams T.D., Jung S.-O., and Lee J.-S. cDNA cloning and expression of a cytochrome P450 1A (CYP1A) gene from the hermaphroditic fish Rivulus marmoratus. Mar. Pollut. Bull. 51 (2005) 769-775
19. Lee Y.-M., Jung S.-O., Seo J.S., Yoon Y.-D., and Lee J.-S. Cloning of Ki-ras and Ha-ras cDNAs from the hermaphroditic fish Rivulus marmoratus (Cyprinodontiformes, Rivulidae) and its expression after exposure to 4-nonylphenol. Mar. Environ. Res. 62 (2006) S136-S140
20. Lee Y.-M., Chang S.-Y., Jung S.O., Kweon H.-S., and Lee J.-S. Cloning and expression of alpha class glutathione S-transferase gene from the small hermaphroditic fish Rivulus marmoratus (Cyprinodontiformes, Rivulidae). Mar. Pollut. Bull. 51 (2006) 776-783
21. Lee Y.-M., Rhee J.-S., Kim I.-C., Raisuddin S., and Lee J.-S. Mining of biomarker genes from expressed sequence tags and differential display reverse transcriptase-polymerase chain reaction in the self-fertilizing fish, Kryptolebias marmoratus and their expression patterns in response to exposure to an endocrine-disrupting alkylphenol, bisphenol A. Mol. Cells 23 (2007) 287-303
22. Lee J.-S., Raisuddin S., and Schlenk D. Kryptolebias marmoratus (Poey, 1880) a potential model species for molecular carcinogenesis and ecotoxicogenomics. J. Fish Biol. 71 (2008) 1871-1889
23. Lee Y.-M., Rhee J.-S., Hwang D.-S., Kim I.-C., Raisuddin S., and Lee J.-S. p53 gene expression is modulated by endocrine disrupting chemicals in the hermaphroditic fish, Kryptolebias marmoratus. Comp. Biochem. Physiol. 147C (2008) 150-157
24. Lee Y.-M., Raisuddin S., Rhee J.S., Ki J.-S., Kim I.-C., and Lee J.-S. Modulatory effect of environmental endocrine disruptors on N-ras oncogene expression in the hermaphroditic fish, Kryptolebias marmoratus. Comp. Biochem. Physiol. 147C (2008) 299-305
25. Lin H.C., and Dunson W.A. The effect of salinity on the acute toxicity of cadmium to the tropical, estuarine, hermaphroditic fish, Rivulus marmoratus: a comparison of Cd, Cu, and Zn tolerance with Fundulus heteroclitus. Arch. Environ. Contam. Toxicol. 25 (1993) 41-47
26. -ΔΔC method. Methods 25 (2001) 402-408
27. McClain J.S., Oris J.T., Burton Jr. G.A., and Lattier D. Laboratory and field validation of multiple molecular biomarkers of contaminant exposure in rainbow trout (Oncorhynchus mykiss). Environ. Toxicol. Chem. 22 (2003) 361-370
28. Monserrat J.M., Martínez P.E., Geracitano L.A., Amado L.L., Martins C.M., Pinho G.L., Chaves I.S., Ferreira-Cravo M., Ventura-Lima J., and Bianchini A. Pollution biomarkers in estuarine animals: critical review and new perspectives. Comp. Biochem. Physiol. 146C (2007) 221-234
29. Olsson P.-E., Kling P., Petterson C., and Silversand C. Interaction of cadmium and oestradiol-17β on metallothionein and vitellogenin synthesis in rainbow trout (Oncorhynchus mykiss). Biochem. J. 307 (1995) 197-203
30. Park E.-H., Chang H.-H., Joo W.-N., Chung H.-S., and Kwak H.-S. Assessment of the estuarine hermaphroditic fish Rivulus marmoratus as a useful euryhaline species for acute toxicity tests as shown using cadmium. Can. J. Fish. Aquat. Sci. 51 (1994) 280-285
31. Park J.-H., Lee J.-J., Yoon S., Lee J.-S., Choe S.-Y., Choe J., Park E.-H., and Kim C.G. Genomic cloning of the Hsc71 gene in the hermaphroditic teleost Rivulus marmoratus and analysis of its expression in skeletal muscle: identification of a novel muscle-preferred regulatory element. Nucleic Acids Res. 29 (2001) 3041-3050
32. Smirnov L.P., Sukhovskaya I.V., and Nemova N.N. Effects of environmental factors on low-molecular-weight peptides of fishes: a review. Russ. J. Ecol. 36 (2005) 41-47
33. Theocharis S.E., Margeli A.P., and Koutselinis A. Metallothionein: a multifunctional protein from toxicity to cancer. Int. J. Biol. Markers 18 (2003) 162-169
34. Vasak M. Advances in metallothionein structure and functions. J. Trace Elem. Med. Biol. 19 (2005) 13-17
35. Vergani L., Grattarola M., Borghi C., Dondero F., and Viarengo A. Fish and molluscan metallothioneins. a structural and functional comparison. FEBS J. 272 (2005) 6014-6023
36. Viarengo A., Ponzano E., Dondero F., and Fabbra R. A simple spectrophotometric method for metallothionein evaluation in marine organisms: an application to Mediterranean and Antartic mollusk. Mar. Environ. Res. 44 (1997) 69-84
37. Viarengo A., Burlando B., Ceratto N., and Panfoli I. Antioxidant role of metallothioneins: a comparative overview. Cell. Mol. Biol. 46 (2000) 407-417
38. Werner J., Wautier K., Evans R.E., Baron C.L., Kidd K., and Palace V. Waterborne ethynylestradiol induces vitellogenin and alters metallothionein expression in lake trout (Salvelinus namaycush). Aquat. Toxicol. 62 (2003) 321-328
39. Werner J., Palace V., Baron C., Shiu R., and Yarmill A. A real-time PCR method for the quantification of the two Isoforms of metallothionein in lake trout (Salvelinus namaycush). Arch. Environ. Contam. Toxicol. 54 (2008) 84-91
40. Yao C.P., Allen J.W., Mutkus L.A., Xu S.B., Tan K.H., and Aschner M. Foreign metallothionein-I expression by transient transfection in MT-I and MT-II null astrocytes confers increased protection against acute methylmercury cytotoxicity. Brain Res. 855 (2000) 32-38
41. Zafarullah M., Olsson P.E., and Gedamu L. Endogenous and heavy-metal-ion-induced metallothionein gene expression in salmonid tissues and cell lines. Gene 83 (1989) 85-93
42. Zhou Y., Li L., and Ru B. Expression, purification and characterization of beta domain and beta domain dimer of metallothionein. Biochim. Biophys. Acta. 1524 (2000) 87-93