-
1
-
-
42349112088
-
Genome-wide association studies for complex traits: Consensus, uncertainty and challenges
-
McCarthy MI, Abecasis GR, Cardon LR, Goldstein DB, Little J, Ioannidis JP, Hirschhorn JN: Genome-wide association studies for complex traits: Consensus, uncertainty and challenges. Nat Rev Genet 9: 356-369, 2008
-
(2008)
Nat Rev Genet
, vol.9
, pp. 356-369
-
-
McCarthy, M.I.1
Abecasis, G.R.2
Cardon, L.R.3
Goldstein, D.B.4
Little, J.5
Ioannidis, J.P.6
Hirschhorn, J.N.7
-
2
-
-
34548028293
-
The impact of genotype frequencies on the clinical validity of genomic profiling for predicting common chronic diseases
-
Janssens AC, Moonesinghe R, Yang Q, Steyerberg EW, van Duijn CM, Khoury MJ: The impact of genotype frequencies on the clinical validity of genomic profiling for predicting common chronic diseases. Genet Med 9: 528-535, 2007
-
(2007)
Genet Med
, vol.9
, pp. 528-535
-
-
Janssens, A.C.1
Moonesinghe, R.2
Yang, Q.3
Steyerberg, E.W.4
van Duijn, C.M.5
Khoury, M.J.6
-
4
-
-
40149111451
-
What can genome-wide association studies tell us about the genetics of common disease?
-
Iles MM: What can genome-wide association studies tell us about the genetics of common disease? PLoS Genet 4: e33, 2008
-
(2008)
PLoS Genet
, vol.4
-
-
Iles, M.M.1
-
5
-
-
41149120561
-
A critical appraisal of the scientific basis of commercial genomic profiles used to assess health risks and personalize health interventions
-
Janssens AC, Gwinn M, Bradley LA, Oostra BA, van Duijn CM, Khoury MJ: A critical appraisal of the scientific basis of commercial genomic profiles used to assess health risks and personalize health interventions. Am J Hum Genet 82: 593-599, 2008
-
(2008)
Am J Hum Genet
, vol.82
, pp. 593-599
-
-
Janssens, A.C.1
Gwinn, M.2
Bradley, L.A.3
Oostra, B.A.4
van Duijn, C.M.5
Khoury, M.J.6
-
6
-
-
85190670206
-
-
Grant SF, Thorleifsson G, Reynisdottir I, Benediktsson R, Manolescu A, Sainz J, Helgason A, Stefansson H, Emilsson V, Helgadottir A, Styrkarsdottir U, Magnusson KP, Walters GB, Palsdottir E, Jonsdottir T, Gudmundsdottir T, Gylfason A, Saemundsdottir J, Wilensky RL, Reilly MP, Rader DJ, Bagger Y, Christiansen C, Gudnason V, Sigurdsson G, Thorsteinsdottir U, Gulcher JR, Kong A, Stefansson K: Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes. Nat Genet 38: 320-323, 2006
-
Grant SF, Thorleifsson G, Reynisdottir I, Benediktsson R, Manolescu A, Sainz J, Helgason A, Stefansson H, Emilsson V, Helgadottir A, Styrkarsdottir U, Magnusson KP, Walters GB, Palsdottir E, Jonsdottir T, Gudmundsdottir T, Gylfason A, Saemundsdottir J, Wilensky RL, Reilly MP, Rader DJ, Bagger Y, Christiansen C, Gudnason V, Sigurdsson G, Thorsteinsdottir U, Gulcher JR, Kong A, Stefansson K: Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes. Nat Genet 38: 320-323, 2006
-
-
-
-
7
-
-
85190704908
-
Association analysis of European-derived type 2 diabetes SNPs from whole genome association studies in African Americans
-
April 28, epub ahead of print
-
Lewis JP, Palmer ND, Hicks PJ, Sale MM, Langefeld CD, Freedman BI, Divers J, Bowden DW: Association analysis of European-derived type 2 diabetes SNPs from whole genome association studies in African Americans. Diabetes April 28, 2008 [epub ahead of print]
-
(2008)
Diabetes
-
-
Lewis, J.P.1
Palmer, N.D.2
Hicks, P.J.3
Sale, M.M.4
Langefeld, C.D.5
Freedman, B.I.6
Divers, J.7
Bowden, D.W.8
-
8
-
-
38949083548
-
Association of TCF7L2 polymorphisms with susceptibility to type 2 diabetes in 4,087 Japanese subjects
-
Miyake K, Horikawa Y, Hara K, Yasuda K, Osawa H, Furuta H, Hirota Y, Yamagata K, Hinokio Y, Oka Y, Iwasaki N, Iwamoto Y, Yamada Y, Seino Y, Maegawa H, Kashiwagi A, Yamamoto K, Tokunaga K, Takeda J, Makino H, Nanjo K, Kadowaki T, Kasuga M: Association of TCF7L2 polymorphisms with susceptibility to type 2 diabetes in 4,087 Japanese subjects. J Hum Genet 53: 174-180, 2008
-
(2008)
J Hum Genet
, vol.53
, pp. 174-180
-
-
Miyake, K.1
Horikawa, Y.2
Hara, K.3
Yasuda, K.4
Osawa, H.5
Furuta, H.6
Hirota, Y.7
Yamagata, K.8
Hinokio, Y.9
Oka, Y.10
Iwasaki, N.11
Iwamoto, Y.12
Yamada, Y.13
Seino, Y.14
Maegawa, H.15
Kashiwagi, A.16
Yamamoto, K.17
Tokunaga, K.18
Takeda, J.19
Makino, H.20
Nanjo, K.21
Kadowaki, T.22
Kasuga, M.23
more..
-
9
-
-
33751369509
-
Common variants in the TCF7L2 gene and predisposition to type 2 diabetes in UK European Whites, Indian Asians and Afro-Caribbean men and women
-
Humphries SE, Gable D, Cooper JA, Ireland H, Stephens JW, Hurel SJ, Li KW, Palmen J, Miller MA, Cappuccio FP, Elkeles R, Godsland I, Miller GJ, Talmud PJ: Common variants in the TCF7L2 gene and predisposition to type 2 diabetes in UK European Whites, Indian Asians and Afro-Caribbean men and women. J Mol Med 84: 1005-1014, 2006
-
(2006)
J Mol Med
, vol.84
, pp. 1005-1014
-
-
Humphries, S.E.1
Gable, D.2
Cooper, J.A.3
Ireland, H.4
Stephens, J.W.5
Hurel, S.J.6
Li, K.W.7
Palmen, J.8
Miller, M.A.9
Cappuccio, F.P.10
Elkeles, R.11
Godsland, I.12
Miller, G.J.13
Talmud, P.J.14
-
10
-
-
34948819195
-
Variants of the transcription factor 7-like 2 (TCF7L2) gene are associated with type 2 diabetes in an African-American population enriched for nephropathy
-
Sale MM, Smith SG, Mychaleckyj JC, Keene KL, Langefeld CD, Leak TS, Hicks PJ, Bowden DW, Rich SS, Freedman BI: Variants of the transcription factor 7-like 2 (TCF7L2) gene are associated with type 2 diabetes in an African-American population enriched for nephropathy. Diabetes 56: 2638-2642, 2007
-
(2007)
Diabetes
, vol.56
, pp. 2638-2642
-
-
Sale, M.M.1
Smith, S.G.2
Mychaleckyj, J.C.3
Keene, K.L.4
Langefeld, C.D.5
Leak, T.S.6
Hicks, P.J.7
Bowden, D.W.8
Rich, S.S.9
Freedman, B.I.10
-
11
-
-
34547585382
-
Variation in TCF7L2 influences therapeutic response to sulfonylureas: A GoDARTs study
-
Pearson ER, Donnelly LA, Kimber C, Whitley A, Doney AS, McCarthy MI, Hattersley AT, Morris AD, Palmer CN: Variation in TCF7L2 influences therapeutic response to sulfonylureas: A GoDARTs study. Diabetes 56: 2178-2182, 2007
-
(2007)
Diabetes
, vol.56
, pp. 2178-2182
-
-
Pearson, E.R.1
Donnelly, L.A.2
Kimber, C.3
Whitley, A.4
Doney, A.S.5
McCarthy, M.I.6
Hattersley, A.T.7
Morris, A.D.8
Palmer, C.N.9
-
12
-
-
42149181801
-
Transcription factor 7-like 2 polymorphism and colon cancer
-
Slattery ML, Folsom AR, Wolff R, Herrick J, Caan BJ, Potter JD: Transcription factor 7-like 2 polymorphism and colon cancer. Cancer Epidemiol Biomarkers Prev 17: 978-982, 2008
-
(2008)
Cancer Epidemiol Biomarkers Prev
, vol.17
, pp. 978-982
-
-
Slattery, M.L.1
Folsom, A.R.2
Wolff, R.3
Herrick, J.4
Caan, B.J.5
Potter, J.D.6
-
13
-
-
48649110179
-
Variation in TCF7L2 and increased risk of colon cancer: The Atherosclerosis Risk in Communities (ARIC) Study
-
Folsom AR, Pankow JS, Peacock JM, Bielinski SJ, Heiss G, Boerwinkle E: Variation in TCF7L2 and increased risk of colon cancer: The Atherosclerosis Risk in Communities (ARIC) Study. Diabetes Care 31: 905-909, 2008
-
(2008)
Diabetes Care
, vol.31
, pp. 905-909
-
-
Folsom, A.R.1
Pankow, J.S.2
Peacock, J.M.3
Bielinski, S.J.4
Heiss, G.5
Boerwinkle, E.6
-
14
-
-
54049119236
-
TCF7L2 variants associate with CKD progression and renal function in population-based cohorts
-
Köttgen A, Hwang S-J, Rampersaud E, Coresh J, North KE, Pankow JS, Meigs JB, Florez JC, Parsa A, Levy D, Boerwinkle E, Shuldiner AR, Fox CS, Kao WH: TCF7L2 variants associate with CKD progression and renal function in population-based cohorts. J Am Soc Nephrol 19: 1989-1999, 2008
-
(2008)
J Am Soc Nephrol
, vol.19
, pp. 1989-1999
-
-
Köttgen, A.1
Hwang, S.-J.2
Rampersaud, E.3
Coresh, J.4
North, K.E.5
Pankow, J.S.6
Meigs, J.B.7
Florez, J.C.8
Parsa, A.9
Levy, D.10
Boerwinkle, E.11
Shuldiner, A.R.12
Fox, C.S.13
Kao, W.H.14
-
15
-
-
0033645239
-
Parental transmission of type 2 diabetes: The Framingham Offspring Study
-
Meigs JB, Cupples LA, Wilson PW: Parental transmission of type 2 diabetes: The Framingham Offspring Study. Diabetes 49: 2201-2207, 2000
-
(2000)
Diabetes
, vol.49
, pp. 2201-2207
-
-
Meigs, J.B.1
Cupples, L.A.2
Wilson, P.W.3
-
16
-
-
40049101431
-
Genomewide association studies: Progress and potential for drug discovery and development
-
Kingsmore SF, Lindquist IE, Mudge J, Gessler DD, Beavis WD: Genomewide association studies: Progress and potential for drug discovery and development. Nat Rev Drug Discov 7: 221-230, 2008
-
(2008)
Nat Rev Drug Discov
, vol.7
, pp. 221-230
-
-
Kingsmore, S.F.1
Lindquist, I.E.2
Mudge, J.3
Gessler, D.D.4
Beavis, W.D.5
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