Protein S down-regulates factor Xase activity independent of activated protein C: Specific binding of factor VIII(a) to protein S inhibits interactions with factor IXa

British Journal of Haematology

Volumn 143, Issue 3, 2008, Pages 409-420

  Takeyama, Masahiro ^a   Nogami, Keiji ^a   Saenko, Evgueni L ^b   Soeda, Tetsuhiro ^a   Nishiya, Katsumi ^a   Ogiwara, Kenichi ^a   Yoshioka, Akira ^a   Shima, Midori ^a  

^a NARA MEDICAL UNIVERSITY   (Japan)

^b UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

Down regulation; Factor IXa; Factor VIII(a); Protein S; Tenase complex

Indexed keywords

ACTIVATED PROTEIN C; BLOOD CLOTTING FACTOR; BLOOD CLOTTING FACTOR 10A; BLOOD CLOTTING FACTOR 8A; BLOOD CLOTTING FACTOR 9A; FACTOR XASE; PROTEIN S; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; DOWN REGULATION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME IMMOBILIZATION; ENZYME INHIBITION; ENZYME KINETICS; ENZYME LINKED IMMUNOSORBENT ASSAY; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN PURIFICATION; SURFACE PLASMON RESONANCE; WESTERN BLOTTING;

BINDING, COMPETITIVE; CYSTEINE ENDOPEPTIDASES; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; FACTOR IXA; FACTOR VIIIA; FACTOR X; HUMANS; NEOPLASM PROTEINS; PHOSPHOLIPIDS; PROTEIN C; PROTEIN S; RECOMBINANT PROTEINS; VON WILLEBRAND FACTOR;

EID: 54049087874     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/j.1365-2141.2008.07366.x     Document Type: Article

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