메뉴 건너뛰기




Volumn 15, Issue 8, 2008, Pages 493-501

Polymeric nanoparticles for enhancing antiretroviral drug therapy

Author keywords

AIDS; Antiretroviral; HIV; Nanoparticles; Novel drug delivery

Indexed keywords

ANTIRETROVIRUS AGENT; CGP 57813; CGP 70726; CHOLESTERYL HYDROGEN SUCCINATE; DELAVIRDINE; DIPALMITOYLPHOSPHATIDYLCHOLINE; EUDRAGIT; HEXYL CYANOACRYLATE; INDINAVIR; INTEGRASE INHIBITOR; LAMIVUDINE; MACROGOL; METHACRYLIC ACID METHYL ESTER; NANOPARTICLE; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLETHANOLAMINE; POLY(ISOHEXYL CYANOACRYLATE); POLYBUTYL CYANOACRYLATE; POLYMER; PROTEINASE INHIBITOR; RNA DIRECTED DNA POLYMERASE INHIBITOR; SAQUINAVIR; SOLID LIPID NANOPARTICLE; STAVUDINE; SULFOPROPYL METHACRYLATE; TAUROCHOLIC ACID; TRIPALMITIN; UNCLASSIFIED DRUG; UNINDEXED DRUG; ZALCITABINE; ZIDOVUDINE;

EID: 54049086948     PISSN: 10717544     EISSN: 15210464     Source Type: Journal    
DOI: 10.1080/10717540802321776     Document Type: Review
Times cited : (48)

References (56)
  • 1
    • 54049123870 scopus 로고    scopus 로고
    • Role of nanotechnology in HIV/AIDS treatment: Potential to overcome the viral reservoir challenge
    • Amiji, M. M., Vyas, T. K., and Shah, L. K. 2006. Role of nanotechnology in HIV/AIDS treatment: potential to overcome the viral reservoir challenge. Discov. Med. 6 (34):157-162.
    • (2006) Discov. Med , vol.6 , Issue.34 , pp. 157-162
    • Amiji, M.M.1    Vyas, T.K.2    Shah, L.K.3
  • 3
    • 0029974417 scopus 로고    scopus 로고
    • Efficiency of nanoparticles as a carrier system for antiviral agents in human immunodeficiency virus-infected human monocytes/ macrophages in vitro
    • Bender, A. R., von Briesen, H., Kreuter, J., Duncan, I. B., and Rubsamen-Waigimann H. 1996. Efficiency of nanoparticles as a carrier system for antiviral agents in human immunodeficiency virus-infected human monocytes/ macrophages in vitro. Antimicrob. Agents Chemother. 40(6):1467-1471.
    • (1996) Antimicrob. Agents Chemother , vol.40 , Issue.6 , pp. 1467-1471
    • Bender, A.R.1    von Briesen, H.2    Kreuter, J.3    Duncan, I.B.4    Rubsamen-Waigimann, H.5
  • 4
    • 0034014397 scopus 로고    scopus 로고
    • Long-term sustained delivery of 3′-azido- 2′3′-dideoxythymidine in vivo by means of HA and TCP delivery devices
    • Benghuzzi, H. 2006. Long-term sustained delivery of 3′-azido- 2′3′-dideoxythymidine in vivo by means of HA and TCP delivery devices. Biomed. Sci. Instrum. 36:343-348.
    • (2006) Biomed. Sci. Instrum , vol.36 , pp. 343-348
    • Benghuzzi, H.1
  • 5
    • 0035660823 scopus 로고    scopus 로고
    • Formulation and cytotoxicity of combined cyclodextrin poly(alkylcyanoacrylate) nanoparticles on Caco-2 cells monolayers intended for oral administration of saquinavir
    • Boudad, H., Legrand, P., Appel, M., Coconnier, M. H., and Ponchel G. 2001. Formulation and cytotoxicity of combined cyclodextrin poly(alkylcyanoacrylate) nanoparticles on Caco-2 cells monolayers intended for oral administration of saquinavir. STP Pharma. Sci. 11(5):369-375.
    • (2001) STP Pharma. Sci , vol.11 , Issue.5 , pp. 369-375
    • Boudad, H.1    Legrand, P.2    Appel, M.3    Coconnier, M.H.4    Ponchel, G.5
  • 6
    • 4444379133 scopus 로고    scopus 로고
    • Nanoparticle and targeted systems for cancer therapy
    • Brannon-Peppas, L., and Blanchette, J. O. 2004. Nanoparticle and targeted systems for cancer therapy. Adv. Drug. Deliv. Rev. 56(11):1649-1659.
    • (2004) Adv. Drug. Deliv. Rev , vol.56 , Issue.11 , pp. 1649-1659
    • Brannon-Peppas, L.1    Blanchette, J.O.2
  • 7
    • 0030726383 scopus 로고    scopus 로고
    • Host factors in the pathogenesis of HIV disease
    • Cohen, O. J., Kinter, A., and Fauci, A. S.. 1997. Host factors in the pathogenesis of HIV disease. Immunol. Rev. 159:31-48.
    • (1997) Immunol. Rev , vol.159 , pp. 31-48
    • Cohen, O.J.1    Kinter, A.2    Fauci, A.S.3
  • 8
    • 0343953614 scopus 로고    scopus 로고
    • Oral bioavailability of a poorly water soluble HIV-1 protease inhibitor incorporated into pH-sensitive particles: Effect of the particle size and nutritional state
    • De Jaeghere, F., Allemann, E., Kubel, F., Galli, B., Cozens, R., Doelker, E., and Gurny, R.. 2000. Oral bioavailability of a poorly water soluble HIV-1 protease inhibitor incorporated into pH-sensitive particles: effect of the particle size and nutritional state. J. Control Release 68(2):291-298.
    • (2000) J. Control Release , vol.68 , Issue.2 , pp. 291-298
    • De Jaeghere, F.1    Allemann, E.2    Kubel, F.3    Galli, B.4    Cozens, R.5    Doelker, E.6    Gurny, R.7
  • 9
    • 0034743412 scopus 로고    scopus 로고
    • Targeting of 3′-azido 3′-deoxythymidine (AZT)-loaded poly(isohexylcyanoacrylate) nanospheres to the gastrointestinal mucosa and associated lymphoid tissues
    • Dembri, A., Montisci, M. J., Gantier, J. C., Chacun, H., and Ponchel, G. 2001. Targeting of 3′-azido 3′-deoxythymidine (AZT)-loaded poly(isohexylcyanoacrylate) nanospheres to the gastrointestinal mucosa and associated lymphoid tissues. Pharm. Res. 18(4):467-473.
    • (2001) Pharm. Res , vol.18 , Issue.4 , pp. 467-473
    • Dembri, A.1    Montisci, M.J.2    Gantier, J.C.3    Chacun, H.4    Ponchel, G.5
  • 10
    • 0030943130 scopus 로고    scopus 로고
    • Pharmacokinetics and tissue distribution of a long circulating liposomal formulation of 2′3′ dideoxyinosine
    • Dipali, S. R., Lin, Y. J., Ravis, G. V., and Betageri, G. V. 1997. Pharmacokinetics and tissue distribution of a long circulating liposomal formulation of 2′3′ dideoxyinosine. Int. J. Pharmaceutics 152(1):89-97.
    • (1997) Int. J. Pharmaceutics , vol.152 , Issue.1 , pp. 89-97
    • Dipali, S.R.1    Lin, Y.J.2    Ravis, G.V.3    Betageri, G.V.4
  • 12
    • 33845965983 scopus 로고    scopus 로고
    • Laboratory investigations for the morphologic, pharmacokinetic, and anti-retroviral properties of indinavir nanoparticles in human monocyte-derived macrophages
    • Dou, H., Morehead, J., Destache, C. J., Kingsley, J. D., Shlyakhtenko, L., Zhou, Y., Chaubal, M., Werling, J., Kipp, J., Rabinow, B. E., and Gendelman, H. E. 2007. Laboratory investigations for the morphologic, pharmacokinetic, and anti-retroviral properties of indinavir nanoparticles in human monocyte-derived macrophages. Virology 358(1):148-158.
    • (2007) Virology , vol.358 , Issue.1 , pp. 148-158
    • Dou, H.1    Morehead, J.2    Destache, C.J.3    Kingsley, J.D.4    Shlyakhtenko, L.5    Zhou, Y.6    Chaubal, M.7    Werling, J.8    Kipp, J.9    Rabinow, B.E.10    Gendelman, H.E.11
  • 13
    • 33847116733 scopus 로고    scopus 로고
    • Poly (propyleneimine) dendrimer-based nanocontainers for targeting of efavirenz to human monocytes/macrophages in vitro
    • Dutta, T., Agashe, H. B., Garg, M., Balasubramanium, P., Kabra, M., and Jain, N. K. 2007. Poly (propyleneimine) dendrimer-based nanocontainers for targeting of efavirenz to human monocytes/macrophages in vitro. J. Drug Target 15(1):89-98.
    • (2007) J. Drug Target , vol.15 , Issue.1 , pp. 89-98
    • Dutta, T.1    Agashe, H.B.2    Garg, M.3    Balasubramanium, P.4    Kabra, M.5    Jain, N.K.6
  • 14
    • 0344092998 scopus 로고
    • The acquired immunodeficiency syndrome (AIDS)
    • New York: McGraw-Hi Publishing
    • Fauci, A. S., and Lane, H. C. 1991. The acquired immunodeficiency syndrome (AIDS): in Harrison's Principles of Internal Medicine. New York: McGraw-Hi Publishing. 1402-1410.
    • (1991) Harrison's Principles of Internal Medicine , pp. 1402-1410
    • Fauci, A.S.1    Lane, H.C.2
  • 15
    • 0036467286 scopus 로고    scopus 로고
    • Targeted delivery of indinavir to HIV-1 primary reservoirs with immunoliposomes
    • Gagne, J. F., Desormeaux, A., Perron, S., Tremblay, M. J., and Bergeron, M. G. 2002. Targeted delivery of indinavir to HIV-1 primary reservoirs with immunoliposomes. Biochim. Biophys. Acta. 1558(2):198-210.
    • (2002) Biochim. Biophys. Acta , vol.1558 , Issue.2 , pp. 198-210
    • Gagne, J.F.1    Desormeaux, A.2    Perron, S.3    Tremblay, M.J.4    Bergeron, M.G.5
  • 16
    • 33646163652 scopus 로고    scopus 로고
    • A review of vaccine research and development: The human immunodeficiency virus (HIV)
    • Girard, M. P., Osmanov, S. K., and Kieny, M. P. 2006. A review of vaccine research and development: the human immunodeficiency virus (HIV). Vaccine 24(19):4062-4081.
    • (2006) Vaccine , vol.24 , Issue.19 , pp. 4062-4081
    • Girard, M.P.1    Osmanov, S.K.2    Kieny, M.P.3
  • 17
    • 1142285520 scopus 로고    scopus 로고
    • Ascorbyl palmitate vesicles (Aspasomes): Formation, characterization and applications
    • Gopinath, D., Ravi, D., Rao, B. R., Apte, S. S., Renuka, D., and Rambhau, D. 2004. Ascorbyl palmitate vesicles (Aspasomes): formation, characterization and applications. Int. J. Pharm. 271(1-2):95-113.
    • (2004) Int. J. Pharm , vol.271 , Issue.1-2 , pp. 95-113
    • Gopinath, D.1    Ravi, D.2    Rao, B.R.3    Apte, S.S.4    Renuka, D.5    Rambhau, D.6
  • 18
    • 0031790931 scopus 로고    scopus 로고
    • Solid lipid nanoparticles as drug carriers II. Plasma stability and biodistribution of solid lipid nanoparticles containing the lipophilic prodrug 3′-azido-3′- deoxythymidine palmitate in mice
    • Heiati, H., Tawashi, R., and Phillips, N. C. 1998. Solid lipid nanoparticles as drug carriers II. Plasma stability and biodistribution of solid lipid nanoparticles containing the lipophilic prodrug 3′-azido-3′- deoxythymidine palmitate in mice. Int. J. Pharm. 174(1-2):71-80.
    • (1998) Int. J. Pharm , vol.174 , Issue.1-2 , pp. 71-80
    • Heiati, H.1    Tawashi, R.2    Phillips, N.C.3
  • 19
    • 0031040884 scopus 로고    scopus 로고
    • Solid lipid nanoparticles as drug carriers 1. Incorporation and retention of the lipophilic prodrug 3′-azido-3′-deoxythymidine palmitate
    • Heiati, H., Tawashi, R., Shivers, R. R., and Phillips, N. C. 1997. Solid lipid nanoparticles as drug carriers 1. Incorporation and retention of the lipophilic prodrug 3′-azido-3′-deoxythymidine palmitate. Int. J. Pharm. 146:123-131.
    • (1997) Int. J. Pharm , vol.146 , pp. 123-131
    • Heiati, H.1    Tawashi, R.2    Shivers, R.R.3    Phillips, N.C.4
  • 20
    • 76849098199 scopus 로고    scopus 로고
    • Cited 24/10/07] Available from
    • Highleyman, L. HIV Drugs and the HIV Lifecycle 2003. [Cited 24/10/07] Available from: http://www.thewellproject.org/en_US/ Treatmentand_Trials/Anti_HIV_Meds/Lifecycle_and_ ARVs.jsp.
    • (2003) HIV Drugs and the HIV Lifecycle
    • Highleyman, L.1
  • 23
    • 38749115449 scopus 로고    scopus 로고
    • Loading efficiency of stavudine on polybutylcyanoacrylate and methylmethacrylate-sulfopropylmethacrylate copolymer nanoparticles
    • Kuo, Y. C., and Kuo, C. Y. 2007. Loading efficiency of stavudine on polybutylcyanoacrylate and methylmethacrylate-sulfopropylmethacrylate copolymer nanoparticles. Int. J. Pharm. 351(1-2):271-281.
    • (2007) Int. J. Pharm , vol.351 , Issue.1-2 , pp. 271-281
    • Kuo, Y.C.1    Kuo, C.Y.2
  • 24
    • 33750512963 scopus 로고    scopus 로고
    • Effect of nanoparticulate polybutylcyanoacrylate and methylmethacrylate-sulfopropylmethacrylate on the permeability of zidovudine and lamivudine across the in vitro blood-brain barrier
    • Kuo, Y. C., and Chen, H. H. 2006. Effect of nanoparticulate polybutylcyanoacrylate and methylmethacrylate-sulfopropylmethacrylate on the permeability of zidovudine and lamivudine across the in vitro blood-brain barrier. Int. J. Pharm. 327(1-2):160-169.
    • (2006) Int. J. Pharm , vol.327 , Issue.1-2 , pp. 160-169
    • Kuo, Y.C.1    Chen, H.H.2
  • 25
    • 54049153352 scopus 로고    scopus 로고
    • Electromagnetic interference in the permeability of saquinavir across the blood-brain barrier using nanoparticulate carriers
    • Kuo, Y. C., and Kuo, C. Y. 2007. Electromagnetic interference in the permeability of saquinavir across the blood-brain barrier using nanoparticulate carriers. Int. J. Pharm.
    • (2007) Int. J. Pharm
    • Kuo, Y.C.1    Kuo, C.Y.2
  • 26
    • 34447268486 scopus 로고    scopus 로고
    • Transport of stavudine, delavirdine, and saquinavir across the blood-brain barrier by polybutylcyanoacrylate, methylmethacrylate-sulfopropylmetheorylate, and solid lipid nanoparticles
    • Kuo, Y. C., and Su, F. L. 2007. Transport of stavudine, delavirdine, and saquinavir across the blood-brain barrier by polybutylcyanoacrylate, methylmethacrylate-sulfopropylmetheorylate, and solid lipid nanoparticles. Int. J. Pharm. 340(1-2):143-152.
    • (2007) Int. J. Pharm , vol.340 , Issue.1-2 , pp. 143-152
    • Kuo, Y.C.1    Su, F.L.2
  • 27
    • 34248136826 scopus 로고    scopus 로고
    • Recent advances in delivery systems for anti-HIV1 therapy
    • Lanao, J. M., Briones, E., and Colino, C. I. 2007. Recent advances in delivery systems for anti-HIV1 therapy. J. Drug. Target. 15(1):21-36.
    • (2007) J. Drug. Target , vol.15 , Issue.1 , pp. 21-36
    • Lanao, J.M.1    Briones, E.2    Colino, C.I.3
  • 28
    • 0028850112 scopus 로고
    • Pharmacokinetics of a novel HIV-1 protease inhibitor incorporated into biodegradable or enteric nanoparticles following intravenous and oral administration to mice
    • Leroux, J. C., Cozens, R., Roesel, J. L., Galli, B., Kubel, F., Doelker, E., and Gurny, R. 1995. Pharmacokinetics of a novel HIV-1 protease inhibitor incorporated into biodegradable or enteric nanoparticles following intravenous and oral administration to mice. J. Pharm. Sci. 84(12):1387-1391.
    • (1995) J. Pharm. Sci , vol.84 , Issue.12 , pp. 1387-1391
    • Leroux, J.C.1    Cozens, R.2    Roesel, J.L.3    Galli, B.4    Kubel, F.5    Doelker, E.6    Gurny, R.7
  • 29
    • 0344352474 scopus 로고    scopus 로고
    • Body distribution of azidothymidine bound to nanoparticles after oral administration
    • Löbenberg, R., Araujo, L., and Kreuter, J. 1997. Body distribution of azidothymidine bound to nanoparticles after oral administration. Eur. J. Pharm. Biopharm. 44(2):127-132.
    • (1997) Eur. J. Pharm. Biopharm , vol.44 , Issue.2 , pp. 127-132
    • Löbenberg, R.1    Araujo, L.2    Kreuter, J.3
  • 30
    • 0032472296 scopus 로고    scopus 로고
    • Body distribution of azidothymidine bound to hexyl-cyanoacrylate nanoparticles after i.v. injection to rats
    • Löbenberg, R., Araujo, L., von Briesen, H., Rodgers, E., and Kreuter, J. 1998. Body distribution of azidothymidine bound to hexyl-cyanoacrylate nanoparticles after i.v. injection to rats. J. Control Release 50(1-3):21-30.
    • (1998) J. Control Release , vol.50 , Issue.1-3 , pp. 21-30
    • Löbenberg, R.1    Araujo, L.2    von Briesen, H.3    Rodgers, E.4    Kreuter, J.5
  • 31
    • 0035382490 scopus 로고    scopus 로고
    • Update on the pathology of AIDS
    • Lucas, S. 2001. Update on the pathology of AIDS. Intensive. Crit. Care Nurs. 17(3):155-166.
    • (2001) Intensive. Crit. Care Nurs , vol.17 , Issue.3 , pp. 155-166
    • Lucas, S.1
  • 32
    • 33748971207 scopus 로고    scopus 로고
    • Recent advances in nanotechnology
    • Mamalis, A. G. 2006. Recent advances in nanotechnology. J. Mat. Protec. 181(1-3):52-58.
    • (2006) J. Mat. Protec , vol.181 , Issue.1-3 , pp. 52-58
    • Mamalis, A.G.1
  • 33
    • 0027233867 scopus 로고
    • Drug delivery approaches for anti-HIV drugs
    • Mirchandani, H., and Chien, Y. W. 1993. Drug delivery approaches for anti-HIV drugs. Int. J. Pharm. 95(1-3):1-21.
    • (1993) Int. J. Pharm , vol.95 , Issue.1-3 , pp. 1-21
    • Mirchandani, H.1    Chien, Y.W.2
  • 34
    • 54049126270 scopus 로고    scopus 로고
    • Barriers to HIV care and treatment by doctors: A review of the literature. SA Fam. Pract. 48
    • In press
    • Naidoo, P. Barriers to HIV care and treatment by doctors: a review of the literature. SA Fam. Pract. 48. (In press).
    • Naidoo, P.1
  • 35
    • 11844281473 scopus 로고    scopus 로고
    • Effect of L-menthol and 1,8-cineole on phase behavior and molecular organization of SC lipids and skin permeation of zidovudine
    • Narishetty, S. T., and Panchagnula, R. 2005. Effect of L-menthol and 1,8-cineole on phase behavior and molecular organization of SC lipids and skin permeation of zidovudine. J. Control Release 102(1):59-70.
    • (2005) J. Control Release , vol.102 , Issue.1 , pp. 59-70
    • Narishetty, S.T.1    Panchagnula, R.2
  • 36
    • 0025008853 scopus 로고
    • High levels of unintegrated HIV-1 DNA in brain tissue of AIDS dementia patients
    • Pang, S., Koyanagi, Y., Miles, S., Wiley, C., Vinters, H. V., and Chen, I. S. 1990. High levels of unintegrated HIV-1 DNA in brain tissue of AIDS dementia patients. Nature 343(6253):85-89.
    • (1990) Nature , vol.343 , Issue.6253 , pp. 85-89
    • Pang, S.1    Koyanagi, Y.2    Miles, S.3    Wiley, C.4    Vinters, H.V.5    Chen, I.S.6
  • 37
    • 0037462997 scopus 로고    scopus 로고
    • Biodegradable nanoparticles for drug and gene delivery to cells and tissue
    • Pamyam, J., and Labhasetwar, V. 2003. Biodegradable nanoparticles for drug and gene delivery to cells and tissue. Adv. Drug Deliv. Rev. 55(3):329-347.
    • (2003) Adv. Drug Deliv. Rev , vol.55 , Issue.3 , pp. 329-347
    • Pamyam, J.1    Labhasetwar, V.2
  • 38
    • 34249910894 scopus 로고    scopus 로고
    • Nanotechnology: What it can do for drug delivery
    • Park, K. 2007. Nanotechnology: what it can do for drug delivery. J. Control Release 120(1-2):1-3.
    • (2007) J. Control Release , vol.120 , Issue.1-2 , pp. 1-3
    • Park, K.1
  • 39
    • 76849092398 scopus 로고    scopus 로고
    • Cited 24/20/07, Available from
    • Pieribone, D. The HIV Life Cycle 2002/2003. [Cited 24/20/07]. Available from: http://www.thebody.com/content/art 14193.html.
    • (2002) The HIV Life Cycle
    • Pieribone, D.1
  • 40
    • 33645564927 scopus 로고    scopus 로고
    • Current HIV treatment guidelines - an overview
    • Rathbun, R. C., Lockhart, S. M., and Stephens, J. R. 2006. Current HIV treatment guidelines - an overview. Curr. Pharm. Des. 12(9):1045-1063.
    • (2006) Curr. Pharm. Des , vol.12 , Issue.9 , pp. 1045-1063
    • Rathbun, R.C.1    Lockhart, S.M.2    Stephens, J.R.3
  • 41
  • 42
    • 0026562291 scopus 로고
    • Phagocytosis of nanoparticles by human immunodeficiency virus (HIV)-infected macrophages: A possibility for antiviral drug targeting
    • Schafer, V., von Briesen, H., Andreesen, R., Steffan, A. M., Royer, C., Troster, S., Kreuter, J., and Rubsamen-Waigmann, H. 1992. Phagocytosis of nanoparticles by human immunodeficiency virus (HIV)-infected macrophages: a possibility for antiviral drug targeting. Pharm. Res. 9(4):541-546.
    • (1992) Pharm. Res , vol.9 , Issue.4 , pp. 541-546
    • Schafer, V.1    von Briesen, H.2    Andreesen, R.3    Steffan, A.M.4    Royer, C.5    Troster, S.6    Kreuter, J.7    Rubsamen-Waigmann, H.8
  • 43
    • 0027935380 scopus 로고
    • Nasal absorption of zidovudine and its transport to cerebrospinal fluid in rats
    • Seki, T., Sato, N., Hasegawa, T., Kawaguchi, T., and Juni, K. 1994. Nasal absorption of zidovudine and its transport to cerebrospinal fluid in rats. Biol. Pharm. Bull. 17(8):1135-1137.
    • (1994) Biol. Pharm. Bull , vol.17 , Issue.8 , pp. 1135-1137
    • Seki, T.1    Sato, N.2    Hasegawa, T.3    Kawaguchi, T.4    Juni, K.5
  • 44
    • 33750620330 scopus 로고    scopus 로고
    • Intracellular delivery of saquinavir in biodegradable polymeric nanoparticles for HIV/AIDS
    • Shah, L. K., and Amiji, M. M. 2006. Intracellular delivery of saquinavir in biodegradable polymeric nanoparticles for HIV/AIDS. Pharm. Res. 23(11):2638-2645.
    • (2006) Pharm. Res , vol.23 , Issue.11 , pp. 2638-2645
    • Shah, L.K.1    Amiji, M.M.2
  • 45
    • 54049127890 scopus 로고    scopus 로고
    • Nanotechnology-based delivery systems in HIV/AIDS therapy
    • Shahiwala, A., and Amiji, M. M. 2007. Nanotechnology-based delivery systems in HIV/AIDS therapy. Future HIV Ther. 1(1):49-59.
    • (2007) Future HIV Ther , vol.1 , Issue.1 , pp. 49-59
    • Shahiwala, A.1    Amiji, M.M.2
  • 46
    • 33645878586 scopus 로고    scopus 로고
    • Models of HIV-1 disease: A review of current status
    • Stoddart, C. A., and Reyes, R. A. 2006. Models of HIV-1 disease: a review of current status. Drug Discov. Today: Dis. Models 3:113-119.
    • (2006) Drug Discov. Today: Dis. Models , vol.3 , pp. 113-119
    • Stoddart, C.A.1    Reyes, R.A.2
  • 47
    • 0029360711 scopus 로고
    • Long circulating microparticulate drug carriers
    • Stolnik, S., Illum, L., and Davis, S. S. 1995. Long circulating microparticulate drug carriers. Adv. Drug. Deliv. Rev. 16(2-3):195-214.
    • (1995) Adv. Drug. Deliv. Rev , vol.16 , Issue.2-3 , pp. 195-214
    • Stolnik, S.1    Illum, L.2    Davis, S.S.3
  • 48
    • 34249820576 scopus 로고    scopus 로고
    • Multifunctional nanocarriers
    • Torchilin, V. P. 2006. Multifunctional nanocarriers. Adv. Drug. Deliv. Rev. 58(14):1532-1555.
    • (2006) Adv. Drug. Deliv. Rev , vol.58 , Issue.14 , pp. 1532-1555
    • Torchilin, V.P.1
  • 49
    • 55849087452 scopus 로고    scopus 로고
    • cited 29/11/07, Available from
    • UNAIDS: AIDS epidemic update, 2007. 2007. [cited 29/11/07]. Available from: http://www.unaids.org/en/HIV data/2007EpiUpdate/default.asp.
    • (2007) UNAIDS: AIDS epidemic update
  • 50
    • 34249039982 scopus 로고    scopus 로고
    • Characterization of physicochemical properties and pharmaceutical performance of sucrose co-freeze-dried solid nanoparticulate powders of the anti-HIV agent loviride prepared by media milling
    • Van Eerdenbrugh, B., Froyen, L., Martens, J. A., Blaton, N., Augustijns, P., Brewster, M., and Van den Mooter, G. 2007. Characterization of physicochemical properties and pharmaceutical performance of sucrose co-freeze-dried solid nanoparticulate powders of the anti-HIV agent loviride prepared by media milling. Int. J. Pharm. 338(1-2):198-206.
    • (2007) Int. J. Pharm , vol.338 , Issue.1-2 , pp. 198-206
    • Van Eerdenbrugh, B.1    Froyen, L.2    Martens, J.A.3    Blaton, N.4    Augustijns, P.5    Brewster, M.6    Van den Mooter, G.7
  • 51
    • 0242410776 scopus 로고    scopus 로고
    • Drug delivery to resistant tumors: The potential of poly(alkyl cyanoacrylate) nanoparticles
    • Vauthier, C., Dubernet, C., Chauvierre, C., Brigger, I., and Couvreur, P. 2003. Drug delivery to resistant tumors: the potential of poly(alkyl cyanoacrylate) nanoparticles. J. Control Release 93(2):151-160.
    • (2003) J. Control Release , vol.93 , Issue.2 , pp. 151-160
    • Vauthier, C.1    Dubernet, C.2    Chauvierre, C.3    Brigger, I.4    Couvreur, P.5
  • 52
    • 33644745119 scopus 로고    scopus 로고
    • Development and characterization of emulsomes for sustained and targeted delivery of an antiviral agent to liver
    • Vyas, S. P., Subhedar, R., and Jain, S. 2006. Development and characterization of emulsomes for sustained and targeted delivery of an antiviral agent to liver. J. Pharm. Pharmacol 58(3):321-326.
    • (2006) J. Pharm. Pharmacol , vol.58 , Issue.3 , pp. 321-326
    • Vyas, S.P.1    Subhedar, R.2    Jain, S.3
  • 53
    • 33748669829 scopus 로고    scopus 로고
    • Nanoparticulate drug carriers for delivery of HIV/AIDS therapy to viral reservoir sites
    • Vyas, T. K., Shah, L., and Amiji, M. M. 2006. Nanoparticulate drug carriers for delivery of HIV/AIDS therapy to viral reservoir sites. Expert Opin Drug Deliv. 3(5):613-628.
    • (2006) Expert Opin Drug Deliv , vol.3 , Issue.5 , pp. 613-628
    • Vyas, T.K.1    Shah, L.2    Amiji, M.M.3
  • 54
    • 34547913813 scopus 로고    scopus 로고
    • Chemotherapy with anticancer drugs encapsulated in solid lipid nanoparticles
    • Wong, H. L., Bendayan, R., Rauth, A. M., Li, Y., and Wu, X. Y. 2007. Chemotherapy with anticancer drugs encapsulated in solid lipid nanoparticles. Adv. Drug. Deliv. rev. 59(6):491-504.
    • (2007) Adv. Drug. Deliv. rev , vol.59 , Issue.6 , pp. 491-504
    • Wong, H.L.1    Bendayan, R.2    Rauth, A.M.3    Li, Y.4    Wu, X.Y.5
  • 55
    • 0035183597 scopus 로고    scopus 로고
    • Transbuccal delivery of 2′,3′-dideoxycytidine: In vitro permeation study and histological investigation
    • Xiang, J., Fang, X. and Li, X. 2002. Transbuccal delivery of 2′,3′-dideoxycytidine: in vitro permeation study and histological investigation. Int. J. Pharm. 231(1):57-66.
    • (2002) Int. J. Pharm , vol.231 , Issue.1 , pp. 57-66
    • Xiang, J.1    Fang, X.2    Li, X.3
  • 56
    • 0000320658 scopus 로고    scopus 로고
    • Direct transport of 2′,3′-didehydro-3′-deoxythymidine (D4T) and its ester derivatives to the cerebrospinal fluid via the nasal mucous membrane in rats
    • Yajima, T., Juni, K., Saneyoshi, M., Hasegawa, T., and Kawaguchi, T. 1998. Direct transport of 2′,3′-didehydro-3′-deoxythymidine (D4T) and its ester derivatives to the cerebrospinal fluid via the nasal mucous membrane in rats. Biol. Pharm. Bull. 21(3):272-277.
    • (1998) Biol. Pharm. Bull , vol.21 , Issue.3 , pp. 272-277
    • Yajima, T.1    Juni, K.2    Saneyoshi, M.3    Hasegawa, T.4    Kawaguchi, T.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.