Epigenetic studies should focus on specific cell types

American Journal of Respiratory and Critical Care Medicine

Volumn 178, Issue 8, 2008, Pages 882-883

  Guo, Jia ^a   Williams, Marc A ^a   Georas, Steve N ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGEN; DNA; HISTONE; INTERLEUKIN 4;

ASTHMA; CELL ISOLATION; CHROMATIN ASSEMBLY AND DISASSEMBLY; CHROMATIN STRUCTURE; DNA METHYLATION; ENVIRONMENTAL EXPOSURE; EPIGENETICS; GENE MUTATION; GRANULOCYTE; HUMAN; IMMUNE RESPONSE; LETTER; LUNG ALVEOLUS CELL TYPE 1; LUNG BLOOD VESSEL; LYMPH NODE; MESENCHYMAL STEM CELL; PRIORITY JOURNAL; PROTEIN STRUCTURE; T LYMPHOCYTE ACTIVATION; TH2 CELL; GENETIC EPIGENESIS; GENETICS; LUNG; NOTE; PATHOLOGY;

ASTHMA; DNA; EPIGENESIS, GENETIC; HUMANS; LUNG;

EID: 54049085745     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/ajrccm.178.8.882a     Document Type: Letter

References (6)

1. Miller RL, Ho SM. Environmental epigenetics and asthma: current concepts and call for studies. Am J Respir Crit Care Med 2008;177:567-573.
2. Valapour M, Guo J, Schroeder T, Keen J, Cianferoni A, Casolaro V, Georas SN. Histone deacetylation inhibits IL4 gene expression in T cells. J Allergy Clin Immunol 2002;109:238-245.
3. Ansel KM, Djuretic I, Tanasa B, Rao A. Regulation of Th2 differentiation and IL-4 locus accessibility. Annu Rev Immunol 2006;24:607-656.
4. Georas S, Guo J, De Fanis U, Casolaro V. T-helper cell type-2 regulation in allergic disease. Eur Respir J 2005;26:1119-1137.
5. Vermaelen K, Pauwels R. Pulmonary dendritic cells. Am J Respir Crit Care Med 2005;172:530-551.
6. Williams MA, Georas SN. Gene expression patterns and susceptibility to allergic responses. Exp Rev Clin Immunol 2006;2:59-73.