Genetic variants within the interleukin-1 gene cluster, and risk of incident myocardial infarction, and ischemic stroke: A nested case-control approach

Atherosclerosis

Volumn 201, Issue 1, 2008, Pages 124-129

  Zee, Robert Y L ^a   Hennessey, Hooman ^b   Michaud, Sherri E ^a   Ridker, Paul M ^a  

^a Center for Cardiovascular Disease Prevention   (United States)

^b MCGILL UNIVERSITY   (Canada)

Author keywords

Atherothrombosis; IL1; Polymorphisms

Indexed keywords

INTERLEUKIN 1;

ARTICLE; ATHEROSCLEROSIS; CARDIOVASCULAR RISK; CASE CONTROL STUDY; CEREBROVASCULAR ACCIDENT; CONTROLLED STUDY; DNA POLYMORPHISM; GENE CLUSTER; GENETIC EPIDEMIOLOGY; GENETIC VARIABILITY; GENOTYPE; HEART INFARCTION; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SMOKING; THROMBOSIS;

ADULT; AGED; AGED, 80 AND OVER; CASE-CONTROL STUDIES; COHORT STUDIES; EUROPEAN CONTINENTAL ANCESTRY GROUP; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INCIDENCE; INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN; INTERLEUKIN-1ALPHA; INTERLEUKIN-1BETA; MALE; MIDDLE AGED; MULTIGENE FAMILY; MYOCARDIAL INFARCTION; POLYMORPHISM, SINGLE NUCLEOTIDE; STROKE; UNITED STATES;

EID: 54049084249     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2008.01.004     Document Type: Article

References (15)

1. Ridker P.M., Cushman M., Stampfer M.J., Tracy R.P., and Hennekens C.H. Inflammation, aspirin, and the risk of cardiovascular disease in apparently healthy men. N Engl J Med 336 (1997) 973-979
2. von der Thusen J.H., Kuiper J., van Berkel T.J., and Biessen E.A. Interleukins in atherosclerosis: molecular pathways and therapeutic potential. Pharmacol Rev 55 (2003) 133-166
3. Waehre T., Yndestad A., Smith C., et al. Increased expression of interleukin-1 in coronary artery disease with downregulatory effects of HMG-CoA reductase inhibitors. Circulation 109 (2004) 1966-1972
4. Devlin C.M., Kuriakose G., Hirsch E., and Tabas I. Genetic alterations of IL-1 receptor antagonist in mice affect plasma cholesterol level and foam cell lesion size. Proc Natl Acad Sci U S A 99 (2002) 6280-6285
5. Kirii H., Niwa T., Yamada Y., et al. Lack of interleukin-1beta decreases the severity of atherosclerosis in ApoE-deficient mice. Arterioscler Thromb Vasc Biol 23 (2003) 656-660
6. Nicklin M.J., Hughes D.E., Barton J.L., Ure J.M., and Duff G.W. Arterial inflammation in mice lacking the interleukin 1 receptor antagonist gene. J Exp Med 191 (2000) 303-312
7. Vohnout B., Di Castelnuovo A., Trotta R., et al. Interleukin-1 gene cluster polymorphisms and risk of coronary artery disease. Haematologica 88 (2003) 54-60
8. Manzoli A., Andreotti F., Varlotta C., et al. Allelic polymorphism of the interleukin-1 receptor antagonist gene in patients with acute or stable presentation of ischemic heart disease. Cardiologia 44 (1999) 825-830
9. Iacoviello L., Di Castelnuovo A., Gattone M., et al. Polymorphisms of the interleukin-1beta gene affect the risk of myocardial infarction and ischemic stroke at young age and the response of mononuclear cells to stimulation in vitro. Arterioscler Thromb Vasc Biol 25 (2005) 222-227
10. Physician's health study: aspirin and primary prevention of coronary heart disease. N Engl J Med 1989;321:1825-8.
11. de Kok J.B., Wiegerinck E.T., Giesendorf B.A., and Swinkels D.W. Rapid genotyping of single nucleotide polymorphisms using novel minor groove binding DNA oligonucleotides (MGB probes). Hum Mutat 19 (2002) 554-559
12. Devlin B., and Risch N. A comparison of linkage disequilibrium measures for fine-scale mapping. Genomics 29 (1995) 311-322
13. Stephens M., Smith N.J., and Donnelly P. A new statistical method for haplotype reconstruction from population data. Am J Hum Genet 68 (2001) 978-989
14. Stephens M., and Donnelly P. A comparison of bayesian methods for haplotype reconstruction from population genotype data. Am J Hum Genet 73 (2003) 1162-1169
15. Wallenstein S., Hodge S.E., and Weston A. Logistic regression model for analyzing extended haplotype data. Genet Epidemiol 15 (1998) 173-181