Tissue microarray analysis reveals strong clinical evidence for a close association between loss of annexin A1 expression and nodal metastasis in gastric cancer

Clinical and Experimental Metastasis

Volumn 25, Issue 7, 2008, Pages 695-702

  Yu, Guanzhen ^a,b   Wang, Jiejun ^a   Chen, Ying ^b   Wang, Xi ^a   Pan, Jun ^a   Li, Qiang ^c   Xie, Keping ^c  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b SECOND MILITARY MEDICAL UNIVERSITY   (China)

^c UNIVERSITY OF TEXAS   (United States)

Author keywords

Annexin A1; Gastric cancer; Metastasis; Survival analysis; Tissue microarray

Indexed keywords

BIOLOGICAL MARKER; LIPOCORTIN 1;

ADULT; ARTICLE; CANCER GROWTH; CANCER PATIENT; CANCER STAGING; CANCER SURVIVAL; CELL DIFFERENTIATION; FEMALE; HISTOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; PROTEIN EXPRESSION; STOMACH CANCER; SURVIVAL RATE; TISSUE MICROARRAY;

ADULT; AGED; ANNEXIN A1; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; NEOPLASM STAGING; STOMACH NEOPLASMS; TISSUE ARRAY ANALYSIS;

EID: 53949122896     PISSN: 02620898     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10585-008-9178-y     Document Type: Article

References (32)

1. DM Roder 2002 The epidemiology of gastric cancer Gastric Cancer 5 Suppl 1 5 11 10.1007/s10120-002-0203-6
2. AG Wang SY Yoon JH Oh 2006 Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags Biochem Biophys Res Commun 345 1022 1032 10.1016/j.bbrc.2006.04.175
3. T Yokota S Ishiyama T Saito 2004 Lymph node metastasis as a significant prognostic factor in gastric cancer: a multiple logistic regression analysis Scand J Gastroenterol 39 4 380 384 10.1080/00365520310008629
4. N Shiraishi M Inomata N Osawa K Yasuda Y Adachi S Kitano 2000 Early and late recurrence after gastrectomy for gastric carcinoma. Univariate and multivariate analyses Cancer 89 2 255 261 10.1002/1097-0142(20000715)89: 2≤255::AID-CNCR8≥3.0.CO;2-N
5. V Gerke SE Moss 2002 Annexins: from structure to function Physiol Rev 82 2 331 371
6. JM Iglesias RO Morgan NA Jenkins NG Copeland DJ Gilbert MP Fernandez 2002 Comparative genetics and evolution of annexin A13 as the founder gene of vertebrate annexins Mol Biol Evol 19 5 608 618
7. RO Morgan NA Jenkins DJ Gilbert 1999 Novel human and mouse annexin A10 are linked to the genome duplications during early chordate evolution Genomics 60 1 40 49 10.1006/geno.1999.5895
8. DT Ross U Scherf MB Eisen 2000 Systematic variation in gene expression patterns in human cancer cell lines Nat Genet 24 3 227 235 10.1038/73432
9. Y Guan-Zhen C Ying N Can-Rong W Guo-Dong Q Jian-Xin W Jie-Jun 2007 Reduced protein expression of metastasis-related genes (nm23, KISS1, KAI1 and p53) in lymph node and liver metastases of gastric cancer Int J Exp Pathol 88 3 175 183 10.1111/j.1365-2613.2006.00510.x
10. Y Hippo M Yashiro M Ishii 2001 Differential gene expression profiles of scirrhous gastric cancer cells with high metastatic potential to peritoneum or lymph nodes Cancer Res 61 3 889 895
11. W Wu X Tang W Hu R Lotan WK Hong L Mao 2002 Identification and validation of metastasis-associated proteins in head and neck cancer cell lines by two-dimensional electrophoresis and mass spectrometry Clin Exp Metastasis 19 4 319 326 10.1023/A:1015515119300
12. LH Lim S Pervaiz 2007 Annexin 1: the new face of an old molecule FASEB J 21 4 968 975 10.1096/fj.06-7464rev
13. JC Buckingham CD John E Solito 2006 Annexin 1, glucocorticoids, and the neuroendocrine-immune interface Ann N Y Acad Sci 1088 396 409 10.1196/annals.1366.002
14. XF Bai XG Ni P Zhao 2004 Overexpression of annexin 1 in pancreatic cancer and its clinical significance World J Gastroenterol 10 10 1466 1470
15. SH Ahn H Sawada JY Ro GL Nicolson 1997 Differential expression of annexin I in human mammary ductal epithelial cells in normal and benign and malignant breast tissues Clin Exp Metastasis 15 2 151 156 10.1023/A:1018452810915
16. T Masaki M Tokuda M Ohnishi 1996 Enhanced expression of the protein kinase substrate annexin in human hepatocellular carcinoma Hepatology 24 1 72 81
17. MD Johnson J Kamso-Pratt RB Pepinsky WO Whetsell Jr 1989 Lipocortin-1 immunoreactivity in central and peripheral nervous system glial tumors Hum Pathol 20 8 772 776 10.1016/0046-8177(89)90071-3
18. KL Wang TT Wu E Resetkova 2006 Expression of annexin A1 in esophageal and esophagogastric junction adenocarcinomas: association with poor outcome Clin Cancer Res 12 15 4598 4604 10.1158/1078-0432.CCR-06-0483
19. CP Paweletz DK Ornstein MJ Roth 2000 Loss of annexin 1 correlates with early onset of tumorigenesis in esophageal and prostate carcinoma Cancer Res 60 22 6293 6297
20. A Petrella M Festa SF Ercolino 2006 Annexin-1 downregulation in thyroid cancer correlates to the degree of tumor differentiation Cancer Biol Ther 5 6 643 647
21. JP Rodrigo JM Garcia-Pedrero MP Fernandez RO Morgan C Suarez A Herrero 2005 Annexin A1 expression in nasopharyngeal carcinoma correlates with squamous differentiation Am J Rhinol 19 5 483 487
22. D Shen HR Chang Z Chen 2005 Loss of annexin A1 expression in human breast cancer detected by multiple high-throughput analyses Biochem Biophys Res Commun 326 1 218 227 10.1016/j.bbrc.2004.10.214
23. D Shen F Nooraie Y Elshimali 2006 Decreased expression of annexin A1 is correlated with breast cancer development and progression as determined by a tissue microarray analysis Hum Pathol 37 12 1583 1591 10.1016/j.humpath.2006.06. 001
24. RP Takes RJ Baatenburg de Jong K Wijffels 2001 Expression of genetic markers in lymph node metastases compared with their primary tumours in head and neck cancer J Pathol 194 3 298 302 10.1002/1096-9896(200107)194:3≤298::AID- PATH900≥3.0.CO;2-Q
25. JM Garcia Pedrero MP Fernandez RO Morgan 2004 Annexin A1 down-regulation in head and neck cancer is associated with epithelial differentiation status Am J Pathol 164 1 73 79
26. H Saito T Osaki D Murakami 2006 Effect of age on prognosis in patients with gastric cancer ANZ J Surg 76 6 458 461 10.1111/j.1445-2197.2006.03756.x
27. YQ Zhan XW Sun W Li 2005 [Multivariate prognostic analysis in gastric carcinoma patients after radical operation] Ai Zheng 24 5 596 599
28. E Orsenigo M Carlucci M Braga 2005 [Prognostic factors of gastric neoplasms: experience with 1, 074 cases undergoing surgical treatment at a single center] Suppl Tumori 4 3 S86 S87
29. CW Wu MC Hsieh SS Lo 1997 Prognostic indicators for survival after curative resection for patients with carcinoma of the stomach Dig Dis Sci 42 6 1265 1269 10.1023/A:1018814426278
30. T Yokota S Ishiyama T Saito 2002 Is tumor size a prognostic indicator for gastric carcinoma? Anticancer Res 22 6B 3673 3677
31. JC Yao JF Tseng S Worah 2005 Clinicopathologic behavior of gastric adenocarcinoma in Hispanic patients: analysis of a single institution's experience over 15 years J Clin Oncol 23 13 3094 3103 10.1200/JCO.2005.08.987
32. CH Hsiang T Tunoda YE Whang DR Tyson DK Ornstein 2006 The impact of altered annexin I protein levels on apoptosis and signal transduction pathways in prostate cancer cells Prostate 66 13 1413 1424 10.1002/pros.20457