Improved liquid chromatography-Online radioactivity detection for metabolite profiling

Journal of Chromatography A

Volumn 1209, Issue 1-2, 2008, Pages 128-135

  Cuyckens, Filip ^a   Koppen, Valerie ^a   Kembuegler, Rainer ^b   Leclercq, Laurent ^a  

^a JANSSEN RESEARCH AND DEVELOPMENT   (Belgium)

^b Berthold Technologies   (Germany)

Author keywords

Metabolite profiling; Online radioactivity detection; Radio HPLC; UHPLC; UPLC; VHPLC

Indexed keywords

BIOCHEMISTRY; BODY FLUIDS; CHROMATOGRAPHIC ANALYSIS; CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; RADIATION; RADIOACTIVITY; SEPARATION;

METABOLITE PROFILING; ONLINE RADIOACTIVITY DETECTION; RADIO-HPLC; UHPLC; UPLC; VHPLC;

HIGH PRESSURE LIQUID CHROMATOGRAPHY;

CARBON; HYDROGEN;

ARTICLE; CELL VOLUME; CHEMICAL MODIFICATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; IN VIVO STUDY; METABOLITE; PARTICLE SIZE; PRIORITY JOURNAL; RADIATION DETECTION; SCINTILLATION; SENSITIVITY ANALYSIS;

CARBON RADIOISOTOPES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, LIQUID; RADIOMETRY; REPRODUCIBILITY OF RESULTS;

EID: 53949121143     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2008.09.002     Document Type: Article

References (18)

1. Nguyen D.T.-T., Guillarme D., Rudaz S., and Veuthey J.-L. J. Sep. Sci. 29 (2006) 1836
2. Castro-Perez J., Plumb R., Granger J.H., Beattle I., Joncour K., and Wright A. Rapid Commun. Mass Spectrom. 19 (2005) 843
3. Churchwell M.I., Twaddle N.C., Meeker L.R., and Doerge D.R. J. Chromatogr. B 825 (2005) 134
4. Johnson K.A., and Plumb R. J. Pharm. Biomed. Anal. 39 (2005) 805
5. Pedraglio S., Rozio M.G., Misiano P., Reali V., Dondio G., and Bigogno C. J. Pharm. Biomed. Anal. 44 (2007) 665
6. Walles M., Gauvin C., Morin P.-E., Panetta R., and Ducharme J. J. Sep. Sci. 30 (2007) 1191
7. Beattie I., Joncour K., and Lawson K. LC-GC Eur. 24 (2005) 19
8. Dear G.J., Patel N., Kelly P.J., Webber L., and Yung M. J. Chromatogr. B 844 (2006) 96
9. Bruin G.J., Waldmeier F., Boernsen K.O., Pfaar U., Gross G., and Zollinger M. J. Chromatogr. A 1133 (2006) 184
10. Nassar A.E.F., Bjorge S.M., and Lee D.Y. Anal. Chem. 75 (2003) 785
11. Nassar A.E.F., and Lee D.Y. J. Chromatogr. Sci. 45 (2007) 113
12. Xu L., Adams B., Jeliazkova-Mecheva V.V., Trimble L., Kwei G., and Harsch A. Drug Metab. Dispos. 36 (2008) 731
13. Halász I., Endele R., and Asshauer J. J. Chromatogr. 112 (1975) 37
14. Martin M., and Guiochon G. Anal. Chem. 55 (1983) 2302
15. Thompson J.D., Brown J.S., and Carr P.W. Anal. Chem. 73 (2001) 3340
16. Nguyen D.T.-T., Guillarme D., Heinisch S., Barrioulet M.-P., Rocca J.-L., Rudaz S., and Veuthey J.-L. J. Chromatogr. A 1167 (2007) 76
17. Nguyen D.T.-T., Guillarme D., Rudaz S., and Veuthey J.-L. J. Sep. Sci. 31 (2008) 1050
18. Gika H.G., Theodoridis G., Extance J., Edge A.M., and Wilson I.D. J. Chromatogr. B 871 (2008) 279