What patients and their relatives think about testing for BMPR2

Journal of Genetic Counseling

Volumn 17, Issue 5, 2008, Pages 452-458

  Jones, Diana L ^a   Sandberg, Joanne C ^b   Rosenthal, Mary J ^c   Saunders, Robert C ^a   Hannig, Vickie L ^d   Clayton, Ellen W ^c,d  

^a VANDERBILT UNIVERSITY   (United States)

^b HIGH POINT UNIVERSITY   (United States)

^c VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^d VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Ethics; Genetic predisposition testing; Pulmonary hypertension

Indexed keywords

BONE MORPHOGENETIC PROTEIN RECEPTOR 2;

ADULT; ARTICLE; CLINICAL GENETICS; CONTROLLED STUDY; DISEASE REGISTRY; FAMILY; FEMALE; GENETIC ANALYSIS; HUMAN; MAJOR CLINICAL STUDY; MALE; PATIENT ATTITUDE; PULMONARY HYPERTENSION; RELATIVE; RISK FACTOR; SELF EVALUATION; STRUCTURED INTERVIEW;

BONE MORPHOGENETIC PROTEIN RECEPTORS, TYPE II; DEMOGRAPHY; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENETIC SCREENING; HUMANS; HYPERTENSION, PULMONARY; MALE; MIDDLE AGED; MUTATION;

EID: 53949120877     PISSN: 10597700     EISSN: 15733599     Source Type: Journal    
DOI: 10.1007/s10897-008-9172-1     Document Type: Article

References (17)

1. E. D. Austin J. E. Loyd 2007 Genetics and mediators in pulmonary arterial hypertension Clinics in Chest Medicine 28 1 43 57, vii-viii DOI 10.1016/j.ccm.2006.11.007
2. S. Barnoy 2007 Genetic testing for late-onset diseases: effect of disease controllability, test predictivity, and gender on the decision to take the test Genetic Testing 11 2 187 192 doi:10.1089/gte.2006.0509
3. M. Cappelli L. Surh L. Humphreys S. Verma D. Logan A. Hunter 1999 Psychological and social determinants of women's decisions to undergo genetic counseling and testing for breast cancer Clinical Genetics 55 6 419 430 doi:10.1034/j.1399-0004.1999.550605.x
4. E. W. Clayton 2003 Ethical, Legal, and Social Implications of Genomic Medicine The New England Journal of Medicine 349 562 569 doi:10.1056/ NEJMra012577
5. S. M. Cox 2003 Stories in decisions: how at-risk individuals decide to request predictive testing for Huntington disease Qualitative Sociology 26 2 257 280 doi:10.1023/A:1022971113683
6. Hannig, V. L., Wheeler, L., Phillips, J. A. I., Vnencak-Jones, C. L., Newman, J. H., Clayton, E. W., et al. (2008). Interest in clinical genetic testing for familial pulmonary arterial hypertension (FPAH). American Journal of Respiratory and Critical Care Medicine, 177 (Abstracts), A921.
7. M. Humbert H. Nunes O. Sitbon F. Parent P. Herve G. Simonneau 2001 Risk factors for pulmonary arterial hypertension Clinics in Chest Medicine 22 3 459 475 doi:10.1016/S0272-5231(05)70284-7
8. Lane, K., & Heitman, E. (2007). Role of patient-specific research data in the clinic. Paper presented at the American Society of Bioethics and Humanities Annual Meeting, Washington, DC.
9. C. Lerman J. Seay A. Balshem J. Audrain 1995 Interest in genetic testing among first-degree relatives of breast cancer patients American Journal of Medical Genetics 57 3 385 392 doi:10.1002/ajmg.1320570304
10. E. A. Lientz E. W. Clayton 2000 Psychosocial implications of primary pulmonary hypertension American Journal of Human Genetics 59 Suppl 2 209
11. Loyd, J. E. (2007). National Registry for Familial Primary Pulmonary Hypertension. Retrieved November 11, 2007, from http://www.mc.vanderbilt.edu/ root/vumc.php?site=vupphstudy.
12. M. McGoon D. Gutterman V. Steen R. Barst D. C. McCrory T. A. Fortin 2004 Screening, early detection, and diagnosis of pulmonary arterial hypertension: ACCP evidence-based clinical practice guidelines Chest 126 Suppl 1 14S 34S doi:10.1378/chest.126.1_suppl.14S
13. H. Morisaki N. Nakanishi S. Kyotani A. Takashima H. Tomoike T. Morisaki 2004 BMPR2 mutations found in Japanese patients with familial and sporadic primary pulmonary hypertension Human Mutation 23 6 632 doi:10.1002/humu.9251
14. J. H. Newman R. C. Trembath J. A. Morse E. Grunig J. E. Loyd S. Adnot 2004 Genetic basis of pulmonary arterial hypertension: current understanding and future directions Journal of the American College of Cardiology 43 Suppl 12 33S 39S doi:10.1016/j.jacc.2004.02.028
15. K. Nordin J. Bjork G. Berglund 2004 Factors influencing intention to obtain a genetic test for a hereditary disease in an affected group and in the general public Preventive Medicine 39 6 1107 1114 doi:10.1016/j.ypmed.2004.04. 021
16. B. Sztrymf A. Yaici B. Girerd M. Humbert 2007 Genes and pulmonary arterial hypertension Respiration 74 2 123 132 doi:10.1159/000098818
17. A. M. Walker D. Langleben J. J. Korelitz S. Rich L. J. Rubin B. L. Strom 2006 Temporal trends and drug exposures in pulmonary hypertension: an American experience American Heart Journal 152 3 521 526 doi:10.1016/j.ahj.2006.02.020