Immunocontraception in wild horses: One inoculation provides two years of infertility

Journal of Wildlife Management

Volumn 71, Issue 2, 2007, Pages 662-667

  Turner Jr , John W ^a   Liu, Irwin K M ^b   Flanagan, Douglas R ^c   Rutberg, Allen T ^d   Kirkpatrick, Jay F ^e  

^a MEDICAL COLLEGE OF OHIO   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c UNIVERSITY OF IOWA   (United States)

^d TUFTS UNIVERSITY   (United States)

^e Science and Conservation Center   (United States)

Author keywords

Adjuvant; Controlled release vaccine contraception; Equus caballus; Field study; Free roaming wild horse; Pregnancy testing; Zona pellucida antigen

Indexed keywords

HORSE; INFERTILITY; PEST CONTROL; VACCINATION; VACCINE; WILD POPULATION;

NEVADA; NORTH AMERICA; UNITED STATES;

EQUIDAE; EQUUS CABALLUS; SUS;

EID: 53949102051     PISSN: 0022541X     EISSN: None     Source Type: Journal    
DOI: 10.2193/2005-779     Document Type: Article

References (27)

1. Berger, J. 1986. Wild horses of the Great Basin: social competition and population size. University of Chicago Press, Chicago, Illinois, USA.
2. Eldridge, J. H., R. M. Gilly, J. K. Staas, Z. Moldozeanu, J. K. Meulbroek, and T. R. Tice. 1989. Biodegradable microcapsules: vaccine delivery systems for oral immunization. Current Topics in Microbiology and Immunology 146:59-66.
3. Fayrer-Hosken, R. A., H. Bertschinger, J. W. Turner, Jr., I. K. M. Liu, and J. F. Kirkpatrick. 1997. Management of African elephant populations by immunocontraception. Wildlife Society Bulletin 25:18-21.
4. Garrott, R. A. 1991. Feral horse fertility control potential and limitations. Wildlife Society Bulletin 19:52-58.
5. Gross, J. E. 2000. Genetic and demographic consequences of removals and contraception on wild horses in the Pryor Mountain Wild Horse Range. Pages 105-120 in F. J. Singer and K. A. Schoenecker, editors. Managers' summary-ecological studies of the Pryor Mountain Wild Horse Range, 1992-1997. U.S. Geological Survey, Midcontinent Ecological Science Center, Fort Collins, Colorado, USA.
6. Henneke, D. R., G. D. Potter, J. L. Kreider, and B. F. Yeates. 1983. Relationship between condition score, physical measurements and body fat percentage in females. Equine Veterinary Journal 15:371-372.
7. Kirkpatrick, J. F. 2005. The wild horse fertility control program. Pages 63-75 in A. T. Rutberg, eds. Humane wildlife solutions. The role of immunocontraception. Humane Society Press, Washington, D.C., USA.
8. Kirkpatrick, J. F., I. K. M. Liu, and J. W. Turner, Jr. 1990. Remotelydelivered immunocontraception in feral horses. Wildlife Society Bulletin 18:326-330.
9. Kirkpatrick, J. F., I. K. M. Liu, J. W. Turner, Jr., R. Naugle, and R. Keiper. 1992. Long-term effects of porcine zonae pellucidae immunocontraception on ovarian function of feral horses (Equus caballus). Journal of Reproduction and Fertility 94:437-444.
10. Kirkpatrick, J. F., S. E. Shideler, B. L. Lasley, and J. W. Turner, Jr. 1991. Pregnancy determination in uncaptured feral horses by means of fecal steroid conjugates. Theriogenology 35:753-759.
11. Lasley, B. L., and J. F. Kirkpatrick. 1991. Monitoring ovarian function in captive and free-ranging wildlife by means of urinary fecal steroids. Journal of Zoo and Wildlife Medicine 22:23-31.
12. Liu, I. K. M., M. Bernoco, and M. Feldman. 1989. Contraception in females heteroimmunized with porcine zona pellucida. Journal of Reproduction and Fertility 85:19-29.
13. Newman, M. J., and M. F. Powell. 1995. Immunological and formulation design considerations for subunit vaccines. Pages 1-28 in M. F. Powell and M. J. Newman, editors. Vaccine design, pharmaceutical biotechnology series. Plenum Press, New York, New York, USA.
14. Sanders, L. M., B. A. Kell, G. I. McRae, and G. W. Whitehead. 1986. Prolonged controlled release of nafelin, a luteinizing hormone-releasing hormone analog, from biodegradable polymeric implants: influence of composition and molecular weight of polymer. Journal of Pharmaceutical Sciences 75:356-360.
15. Tracy, M. A., K. L. Ward, L. Firouzabadian, Y. Wang, N. Dong, R. Quan, and Y. Zhang. 1999. Factors affecting the degradation rate of poly(lactide-co-glycolide) microspheres in vivo and in vitro. Biomaterials 20:1057-1062.
16. Turner, J. W., Jr., and J. F. Kirkpatrick. 1991. New developments in feral horse contraception and their potential application to wildlife. Wildlife Society Bulletin 19:350-359.
17. Turner, J. W., Jr., I. K. M. Liu, D. R. Flanagan, K. S. Bynum, and A. T. Rutberg. 2002. Porcine zona pellucida (PZP) immunocontraception of wild horses (Equus caballus) in Nevada: a 10-year study. Reproduction 60: 177-186.
18. Turner, J. W., Jr., I. K. M. Liu, D. R. Flanagan, A. T. Rutberg, and J. F. Kirkpatrick. 2000. Immunocontraception in feral horses: a singleinoculation vaccine providing one year of infertility. Journal of Wildlife Management 65:235-241.
19. Turner, J. W., Jr., I. K. M. Liu, and J. F. Kirkpatrick. 1992. Remotely delivered immunocontraception in captive white-tailed deer. Journal of Wildlife Management 56:154-157.
20. Turner, J. W., Jr., I. K. M. Liu, and J. F. Kirkpatrick. 1996. Remotely delivered immunocontraception in free-roaming feral burros (Equus Asinus). Journal of Reproduction and Fertility 107:31-35.
21. Turner, J. W., Jr., I. K. M. Liu, A. T. Rutberg, and J. F. Kirkpatrick. 1997. Immunocontraception limits foal production in free-roaming feral horses in Nevada. Journal of Wildlife Management 61:873-880.
22. Turner, J. W., Jr., and M. L. Morrison. 2001. Trends in number and survivorship of a feral horse population: influence of mountain lion predation. Southwestern Naturalist 46:183-190.
23. Turner, J. W., Jr., A. Perkins, and J. F. Kirkpatrick. 1981. Elimination marking behavior in feral horses. Canadian Journal of Zoology 59:1561-1566.
24. Wang, H. T., H. Palmer, R. J. Linhardt, D. R. Flanagan, and E. Schmitt. 1990. Degradation of poly(ester) microspheres. Biomaterials 11:679-685.
25. Wang, H. T., E. Schmitt, D. R. Flanagan, and R. J. Linhardt. 1991. Influence of formulation methods in the in vitro controlled release of protein from poly(ester) microspheres. Journal of Controlled Release 17: 23-32.
26. Wolfe, M. L., L. C. Ellis, and R. MacMullen. 1989. Reproductive rates of feral horses and burros. Journal of Wildlife Management 53:916-924.
27. Zar, J. H. 1984. Biostatistical analysis. Second edition. Prentice-Hall, Englewood Cliffs, New Jersey, USA.