Transcriptional analysis of gtfB, gtfC, and gbpB and their putative response regulators in several isolates of Streptococcus mutans

Oral Microbiology and Immunology

Volumn 23, Issue 6, 2008, Pages 466-473

  Stipp, R N ^a   Goncalves R B ^a   Hofling J F ^a   Smith, D J ^b   Mattos Graner, R O ^a  

^a UNIVERSITY OF CAMPINAS   (Brazil)

^b FORSYTH INSTITUTE   (United States)

Author keywords

Gene expression; Genetic diversity; Glucan binding protein; Glucosyltransferase; Streptococcus mutans; Two component system

Indexed keywords

BACTERIAL PROTEIN; GLUCOSYLTRANSFERASE; GLUCOSYLTRANSFERASE B; GLUCOSYLTRANSFERASE C; PROTEIN GPPB; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL GENE; BACTERIAL VIRULENCE; BACTERIUM ISOLATE; CONTROLLED STUDY; GENE EXPRESSION; GENETIC VARIABILITY; NONHUMAN; PLANKTON; REGULATOR GENE; STREPTOCOCCUS MUTANS; TRANSCRIPTION REGULATION;

BACTERIAL PROTEINS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, BACTERIAL; GENES, BACTERIAL; GENES, REGULATOR; GENOTYPE; GLUCANS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, BACTERIAL; STREPTOCOCCUS MUTANS; TRANSCRIPTION, GENETIC; VIRULENCE FACTORS;

EID: 53949084421     PISSN: 09020055     EISSN: 1399302X     Source Type: Journal    
DOI: 10.1111/j.1399-302X.2008.00451.x     Document Type: Article

References (38)

1. Ajdic D, McShan WM, McLaughlin RE et al. Genome sequence of Streptococcus mutans UA159, a cariogenic dental pathogen. Proc Natl Acad Sci U S A 2002 : 99 : 14434 14439.
2. Banas JA, Vickerman MM. Glucan-binding proteins of the oral streptococci. Crit Rev Oral Biol Med 2003 : 14 : 89 99.
3. Biswas S, Biswas I. Regulation of the glucosyltransferase (gtfBC) operon by CovR in Streptococcus mutans. J Bacteriol 2006 : 188 : 988 998.
4. Chia JS, Lee YY, Huang PT, Chen JY. Identification of stress-responsive genes in Streptococcus mutans by differential display reverse transcription-PCR. Infect Immun 2001 : 69 : 2493 2501.
5. Davey ME, O'Toole GA. Microbial biofilms: from ecology to molecular genetics. Microbiol Mol Biol Rev 2000 : 64 : 847 867.
6. Eleaume H, Jabbouri S. Comparison of two standardization methods in real-time quantitative RT-PCR to follow Staphylococcus aureus genes expression during in vitro growth. J Microbiol Methods 2004 : 59 : 363 370.
7. Fujiwara T, Hoshino T, Ooshima T, Hamada S. Differential and quantitative analyses of mRNA expression of glucosyltransferases from Streptococcus mutans MT8148. J Dent Res 2002 : 81 : 109 113.
8. Fujiwara T, Terao Y, Hoshino T et al. Molecular analyses of glucosyltransferase genes among strains of Streptococcus mutans. FEMS Microbiol Lett 1998 : 161 : 331 336.
9. Fukushima K, Okada T, Ochiai K. Production, characterization, and application of monoclonal antibodies which distinguish three glucosyltransferases from Streptococcus mutans. Infect Immun 1993 : 61 : 323 328.
10. Goodman SD, Gao Q. Characterization of the gtfB and gtfC promoters from Streptococcus mutans GS-5. Plasmid 2000 : 43 : 85 98.
11. Idone V, Brendtro S, Gillespie R et al. Effect of an orphan response regulator on Streptococcus mutans sucrose-dependent adherence and cariogenesis. Infect Immun 2003 : 71 : 4351 4360.
12. Klein MI, Bang S, Florio FM et al. Genetic diversity of competence gene loci in clinical genotypes of Streptococcus mutans. J Clin Microbiol 2006 : 44 : 3015 3020.
13. Levesque CM, Voronejskaia E, Huang YC, Mair RW, Ellen RP, Cvitkovitch DG. Involvement of sortase anchoring of cell wall proteins in biofilm formation by Streptococcus mutans. Infect Immun 2005 : 73 : 3773 3777.
14. Li YH, Lau PC, Tang N, Svensater G, Ellen RP, Cvitkovitch DG. Novel two-component regulatory system involved in biofilm formation and acid resistance in Streptococcus mutans. J Bacteriol 2002 : 184 : 6333 6342.
15. Li YH, Tang N, Aspiras MB et al. A quorum-sensing signaling system essential for genetic competence in Streptococcus mutans is involved in biofilm formation. J Bacteriol 2002 : 184 : 2699 2708.
16. Matsumura M, Izumi T, Matsumoto M, Tsuji M, Fujiwara T, Ooshima T. The role of glucan-binding proteins in the cariogenicity of Streptococcus mutans. Microbiol Immunol 2003 : 47 : 213 215.
17. Mattos-Graner RO, Jin S, King WF, Chen T, Smith DJ, Duncan MJ. Cloning of the Streptococcus mutans gene encoding glucan binding protein B and analysis of genetic diversity and protein production in clinical isolates. Infect Immun 2001 : 69 : 6931 6941.
18. Mattos-Graner RO, Li Y, Caufield PW, Duncan M, Smith DJ. Genotypic diversity of mutans streptococci in Brazilian nursery children suggests horizontal transmission. J Clin Microbiol 2001 : 39 : 2313 2316.
19. Mattos-Graner RO, Napimoga MH, Fukushima K, Duncan MJ, Smith DJ. Comparative analysis of Gtf isozyme production and diversity in isolates of Streptococcus mutans with different biofilm growth phenotypes. J Clin Microbiol 2004 : 42 : 4586 4592.
20. Mattos-Graner RO, Porter KA, Smith DJ, Hosogi Y, Duncan MJ. Functional analysis of glucan binding protein B from Streptococcus mutans. J Bacteriol 2006 : 188 : 3813 3825.
21. Mattos-Graner RO, Smith DJ, King WF, Mayer MP. Water-insoluble glucan synthesis by mutans streptococcal strains correlates with caries incidence in 12- to 30-month-old children. J Dent Res 2000 : 79 : 1371 1377.
22. Munro C, Michalek SM, Macrina FL. Cariogenicity of Streptococcus mutans V403 glucosyltransferase and fructosyltransferase mutants constructed by allelic exchange. Infect Immun 1991 : 59 : 2316 2323.
23. Ozaki I, Mizuta T, Zhao G et al. Involvement of the Ets-1 gene in overexpression of matrilysin in human hepatocellular carcinoma. Cancer Res 2000 : 60 : 6519 6525.
24. Qi F, Chen P, Caufield PW. Functional analyses of the promoters in the lantibiotic mutacin II biosynthetic locus in Streptococcus mutans. Appl Environ Microbiol 1999 : 65 : 652 658.
25. Qi F, Merritt J, Lux R, Shi W. Inactivation of the ciaH Gene in Streptococcus mutans diminishes mutacin production and competence development, alters sucrose-dependent biofilm formation, and reduces stress tolerance. Infect Immun 2004 : 72 : 4895 4899.
26. Schneider R, Travers A, Kutateladze T, Muskhelishvili G. A DNA architectural protein couples cellular physiology and DNA topology in Escherichia coli. Mol Microbiol 1999 : 34 : 953 964.
27. Senadheera MD, Guggenheim B, Spatafora GA et al. A VicRK signal transduction system in Streptococcus mutans affects gtfBCD, gbpB, and ftf expression, biofilm formation, and genetic competence development. J Bacteriol 2005 : 187 : 4064 4076.
28. Shemesh M, Tam A, Feldman M, Steinberg D. Differential expression profiles of Streptococcus mutans ftf, gtf and vicR genes in the presence of dietary carbohydrates at early and late exponential growth phases. Carbohydr Res 2006 : 341 : 2090 2097.
29. Smith DJ. Caries vaccines for the twenty-first century. J Dent Educ 2003 : 67 : 1130 1139.
30. Smorawinska M, Kuramitsu HK. Primer extension analysis of Streptococcus mutans promoter structures. Oral Microbiol Immunol 1995 : 10 : 188 192.
31. Tao L, MacAlister TJ, Tanzer JM. Transformation efficiency of EMS-induced mutants of Streptococcus mutans of altered cell shape. J Dent Res 1993 : 72 : 1032 1039.
32. Taylor BL, Zhulin IB. PAS domains: internal sensors of oxygen, redox potential, and light. Microbiol Mol Biol Rev 1999 : 63 : 479 506.
33. Tsumori H, Kuramitsu H. The role of the Streptococcus mutans glucosyltransferases in the sucrose-dependent attachment to smooth surfaces: essential role of the GtfC enzyme. Oral Microbiol Immunol 1997 : 12 : 274 280.
34. Waterhouse JC, Russell RR. Dispensable genes and foreign DNA in Streptococcus mutans. Microbiology 2006 : 152 : 1777 1788.
35. Wexler DL, Hudson MC, Burne RA. Streptococcus mutans fructosyltransferase (ftf) and glucosyltransferase (gtfBC) operon fusion strains in continuous culture. Infect Immun 1993 : 61 : 1259 1267.
36. Yamashita Y, Bowen WH, Burne RA, Kuramitsu HK. Role of the Streptococcus mutans gtf genes in caries induction in the specific-pathogen-free rat model. Infect Immun 1993 : 61 : 3811 3817.
37. Yamashita Y, Tsukioka Y, Nakano Y, Shibata Y, Koga T. Molecular and genetic analysis of multiple changes in the levels of production of virulence factors in a subcultured variant of Streptococcus mutans. FEMS Microbiol Lett 1996 : 144 : 81 87.
38. Yoshida A, Kuramitsu HK. Streptococcus mutans biofilm formation: utilization of a gtfB promoter-green fluorescent protein (PgtfB::gfp) construct to monitor development. Microbiology 2002 : 148 : 3385 3394.