Willow bark extract (Salicis cortex) for gonarthrosis and coxarthrosis - Results of a cohort study with a control group

Phytomedicine

Volumn 15, Issue 11, 2008, Pages 907-913

  Beer, A M ^a   Wegener, T ^b  

^a RUHR UNIVERSITY BOCHUM   (Germany)

^b NONE   (Germany)

Author keywords

Classic naturopathic methods; Degenerative joint complaints; Phytoactive drugs; Willow bark Salicis cortex Ph. Eur

Indexed keywords

OPTOVIT ACTIFLEX; PLANT EXTRACT; SALICIS CORTEX EXTRACT; UNCLASSIFIED DRUG;

ABSENCE OF SIDE EFFECTS; AGED; ARTHRALGIA; ARTICLE; CHRONIC DISEASE; CLINICAL EXAMINATION; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; FEMALE; HEALTH STATUS; HIP OSTEOARTHRITIS; HUMAN; JOINT STIFFNESS; KNEE OSTEOARTHRITIS; MAJOR CLINICAL STUDY; MALE; MEDICINAL PLANT; MULTICENTER STUDY; PATIENT ASSESSMENT; PRIORITY JOURNAL; SALICIS CORTEX; WILLOW;

SALIX;

AGED; CHRONIC DISEASE; FEMALE; HUMANS; MALE; MIDDLE AGED; OSTEOARTHRITIS, HIP; OSTEOARTHRITIS, KNEE; PLANT BARK; PLANT EXTRACTS; PLANTS, MEDICINAL; SALIX; TREATMENT OUTCOME;

EID: 53849126813     PISSN: 09447113     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.phymed.2008.07.010     Document Type: Article

References (19)

1. Beer, A.-M., Loew, D., 2008. Naturheilverfahren bei Rückenschmerzen: Möglichkeiten und Grenzen von Phytopharmaka. MMW-Fortschr. Med. 41 (150).
2. Bellamy N., Buchanan W.W., Goldsmith C.H., Campbell J., and Stitt L.W. Validation study of WOMAC: a health status instrument for measuring clinically important patient relevant outcomes to antirheumatic drug therapy in patients with osteoarthritis of the hip or knee. J. Rheumatol. 15 (1988) 1833-1840
3. BfArM (Federal Institute for Drugs and Medical Devices), 1998. Empfehlungen zur Planung, Durchführung und Auswertung von Anwendungsbeobachtungen, vol. no. 229, dated 04.12.1998.
4. Biegert C., Wagner I., Lüdtke R., Kötter I., Lohmüller C., Günaydin I., Taxis K., and Heide L. Efficacy and safety of willow bark extract in the treatment of osteoarthritis and rheumatoid arthritis: results of 2 randomized double-blind controlled trials. J. Rheumatol. 31 (2004) 2121-2130
5. Chan F., Wong V., Suen B., Wu J., Ching J., Hung L., Hui A., Leung V., Lee V., and Lai L. Combination of a cyclo-oxygenase-2 inhibitor and a proton-pump inhibitor for prevention of recurrent ulcer bleeding in patients at very high risk: a double-blind, randomised trial. Lancet 369 9573 (2007) 1621-1626
6. Chrubasik S., Eisenberg E., Balan E., Weinberger T., Luzzati R., and Conradt C. Treatment of low back pain exacerbations with willow bark extract: a randomised double-blind study. Am. J. Med. 109 (2000) 9-14
7. ESCOP (European Scientific Cooperative on Phytotherapy). Monographs (2003), Thieme, Stuttgart pp. 445-451
8. Keusgen M., and Allgäuer-Lechner C. Weidenrindenextrakt. Vielstoffgemisch gegen Entzündungen und Schmerzen. Pharm. Ztg. 8 (2007) 16-22
9. Koelz H.R., and Michel B. Nichtsteroidale Antirheumatika. Magenschutztherapie oder COX-2-Hemmer?. Dtsch. Ärztebl. 101 (2004) A3041-A3046
10. Kraft K., Loew D., Schneider B., and Kemper F.H. Planung, Durchführung und Auswertung von Anwendungsbeobachtungen. Empfehlungen der Gesellschaft für Phytotherapie (GPHY). Arzneim-Forsch/Drug Res. 47 (1997) 990-994
11. Krivoy N., Pavlotzky E., Chrubasik S., Eisenberg E., and Brook G. Effect of salicis cortex extract on human platelet aggregation. Planta Med. 67 (2001) 209-212
12. März R.W., and Kemper F. Weidenrindenextrakt-Wirkungen und Wirksamkeit Erkenntnisstand zu Pharmakologie, Toxikologie und Klinik. Wien. Med. Wochenschr. 152 (2002) 354-359
13. Schmid B., Lüdtke R., Selbmann H.-K., Kötter I., Tschirdewahn B., Schaffner W., and Heide L. Wirksamkeit und Verträglichkeit eines standardisierten Weidenrindenextraktes bei Arthrose-Patienten: Randomisierte, Placebo-kontrollierte Doppelblindstudie. Z. Rheumatol. 59 (2000) 314-320
14. Schmid B., Kötter I., and Heide L. Pharmacokinetics of salicin after oral administration of a standardised willow bark extract. Eur. J. Clin. Pharmacol. 57 (2001) 387-391
15. Stucki G., Meier D., Stucki S., Michel B.A., Tyndall A.G., and Dick W. Evaluation einer deutschen Version des WOMAC (Western Ontario and McMaster Universities) Arthrose Index. Z. Rheumatol. 55 (1996) 40-49
16. Ulrich-Merzenich, G., Jobst, D., Hartbrod, F., Zeitler, H., Vetter, H., 2008. Comparison of gene- and protein expression profiles of a standardized willow bark extract with Quercetin and non-steroidal anti-inflammatory drugs in human chondrocytes. Planta Med. 74, SL 41, 916.
17. Wegener T., and Schneider B. Working Party of the German Society of Phytotherapy. Proposals to enhance the quality of observational cohort studies. Phytomedicine 10 (2003) 700-707
18. ®) for chronic back pain and arthralgia, a post-authorisation surveillance study. Congress Phytopharmaka and Phytotherapy 2004, Berlin.
19. ®), a seeding trial. Poster. Gemeinsamer Kongress der Schweizerischen Gesellschaft für Rheumatologie und für Physikalische Medizin und Rehabilitation 2004, Locarno.