ExPlain™: Finding upstream drug targets in disease gene regulatory networks

SAR and QSAR in Environmental Research

Volumn 19, Issue 5-6, 2008, Pages 481-494

  Kel, A ^a,b   Voss, N ^a   Valeev, T ^c   Stegmaier, P ^a   Kel Margoulis, O ^a   Wingender, E ^a,d  

^a BIOBASE GMBH   (Germany)

^b INSTITUTE OF CHEMICAL BIOLOGY AND FUNDAMENTAL MEDICINE   (Russian Federation)

^c BoRainbow Inc   (Russian Federation)

^d UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

Composite elements; Drug targets; Microarray data analysis; Promoter analysis; Signal transduction; Transcription factors

Indexed keywords

ACTIVATION ANALYSIS; BACTERIOPHAGES; BINDING SITES; CHEMICAL ACTIVATION; GENETIC ALGORITHMS; MOLECULES; SEARCH ENGINES; TRANSCRIPTION; TRANSCRIPTION FACTORS;

CELLULAR PROCESS; COMPOSITE ELEMENT; COMPOSITE MODULES; DISEASE GENES; DRUG TARGETS; GENE EXPRESSION DATA; GENE REGULATORY NETWORKS; MICROARRAY DATA ANALYSIS; PROMOTER ANALYSIS; SIGNAL TRANSDUCTION PATHWAYS;

SIGNAL TRANSDUCTION;

TRANSCRIPTION FACTOR;

ARTICLE; CHEMISTRY; DNA MICROARRAY; DRUG DESIGN; ENTERITIS; GENE REGULATORY NETWORK; GENETIC DATABASE; METHODOLOGY; PATHOLOGY; PROMOTER REGION; QUANTITATIVE STRUCTURE ACTIVITY RELATION; SIGNAL TRANSDUCTION;

CHEMISTRY, PHARMACEUTICAL; DATABASES, GENETIC; DRUG DESIGN; GENE REGULATORY NETWORKS; INFLAMMATORY BOWEL DISEASES; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROMOTER REGIONS, GENETIC; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS;

EID: 53849125480     PISSN: 1062936X     EISSN: 1029046X     Source Type: Journal    
DOI: 10.1080/10629360802083806     Document Type: Article

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