Preventive effect of Ganoderma amboinense on acetaminophen-induced acute liver injury

Phytomedicine

Volumn 15, Issue 11, 2008, Pages 946-950

  Hsu, Cheng chin ^a   Lin, Ko yen ^a   Wang, Zhi hong ^a   Lin, Wea lung ^a   Yin, Mei chin ^b  

^a CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^b CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Ganoderma amboinense; Glutathione; Hepatotoxicity; Polyphenols

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CATALASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; MALONALDEHYDE; PARACETAMOL; REACTIVE OXYGEN METABOLITE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BAGG ALBINO MOUSE; CONTROLLED STUDY; DIET; ENZYME ACTIVITY; GANODERMA; GANODERMA AMBOINENSE; IN VIVO STUDY; LIVER INJURY; LIVER PROTECTION; LIVER TOXICITY; MALE; MOUSE; NONHUMAN; POWDER; PRIORITY JOURNAL; PROTEIN DEPLETION;

ACETAMINOPHEN; ALANINE TRANSAMINASE; ANIMALS; ASPARTATE AMINOTRANSFERASES; CATALASE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG-INDUCED LIVER INJURY; FLAVONOIDS; GANODERMA; GLUTATHIONE; GLUTATHIONE PEROXIDASE; LIVER; MALE; MALONDIALDEHYDE; MICE; MICE, INBRED BALB C; POLYPHENOLS; PROTECTIVE AGENTS; REACTIVE OXYGEN SPECIES;

GANODERMA; MUS;

EID: 53849110854     PISSN: 09447113     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.phymed.2008.04.011     Document Type: Article

References (22)

1. Chang U.M., Li C.H., Lin L.I., Huang C.P., Kan L.S., and Lin S.B. Ganoderiol F, a ganoderma triterpene, induces senescence in hepatoma HepG2 cells. Life Sci. 79 (2006) 1129-1139
2. Correia H.S., Batista M.T., and Dinis T.C. The activity of an extract and fraction of Agrimonia eupatoria L. against reactive species. Biofactors 29 (2007) 91-104
3. Gamal A.M., Mostafa A.M., Al-Shabanah O.A., Al-Bekairi A.M., and Nagi M.N. Protective effect of arabic gum against acetaminophen-induced hepatotoxicity in mice. Pharmacol. Res. 48 (2003) 631-635
4. Gupta R., Dubey D.K., Kannan G.M., and Flora S.J.S. Concomitant administration of Moringa oleifera seed powder in the remediation of arsenic-induced oxidative stress in mouse. Cell Biol. Int. 31 (2007) 44-56
5. Hsu C.C., Lin C.C., Liao T.S., and Yin M.C. Protective effect of s-allyl cysteine and s-propyl cysteine on acetaminophen-induced hepatotoxicity in mice. Food Chem. Toxicol. 44 (2006) 393-397
6. Kimura Y., Taniguchi M., and Baba K. Antitumor and antimetastatic effects on liver of triterpenoid fractions of Ganoderma lucidum: mechanism of action and isolation of an active substance. Anticancer Res. 22 (2002) 3309-3318
7. Li C.H., Chen P.Y., Chang U.M., Kan L.S., Fang W.H., Tsai K.S., and Lin S.B. Ganoderic acid X, a lanostanoid triterpene, inhibits topoisomerases and induces apoptosis of cancer cells. Life Sci. 77 (2005) 252-265
8. Lowry O.H., Rosebrough N.J., and Farr A.L. Protein determination with the Folin phenol reagent. J. Biol. Chem. 193 (1951) 265-275
9. Masubuchi Y., Suda C., and Horie T. Involvement of mitochondrial permeability transition in acetaminophen-induced liver injury in mice. J. Hepatol. 42 (2005) 110-116
10. Meister A. Glutathione deficiency produced by inhibition of its synthesis, and its reversal; applications in research and therapy. Pharmacol. Ther. 51 (1991) 155-194
11. Nelson S.D. Molecular mechanisms of hepatotoxicity caused by acetaminophen. Semin. Liver Dis. 10 (1990) 267-278
12. Oz H.S., McClain C.J., Nagasawa H.T., Ray M.B., de Villiers W.J., and Chen T.S. Diverse antioxidants protect against acetaminophen hepatotoxicity. J. Biochem. Mol. Toxicol. 18 (2004) 361-368
13. SAS Institute. StatView Reference (1999), SAS Publishing, Cary, NC
14. Shaio M.S. Natural products of the medicinal fungus Ganoderma lucidum: occurrence, biological activities and pharmacological functions. Chem. Rec. 3 (2003) 172-180
15. Shiao M.S., Lee K.R., Lin L.J., and Wang C.T. Natural products and biological activities of the Chinese medical fungus, Ganoderma lucidum. In: Ho C.T., Osawa T., Huang M.T., and Rosen R.T. (Eds). Food Phytochemicals for Cancer Prevention II: Teas, Spices, and Herbs (1994), American Chemical Society, Washington, DC 342-354
16. Song Z., McClain C.J., and Chen T. S-adenosylmethionine protects against acetaminophen-induced hepatotoxicity in mice. Pharmacology 71 (2004) 199-208
17. Taga M.S., Miller E.E., and Pratt D.E. Chia seeds as a source of natural lipid antioxidants. J. Am. Oil Chem. Soc. 61 (1984) 928-931
18. Thyagarajan A., Jiang J., Hopf A., Adamec J., and Sliva D. Inhibition of oxidative stress-induced invasiveness of cancer cells by Ganoderma lucidum is mediated through the suppression of interleukin-8 secretion. Int. J. Mol. Med. 18 (2006) 657-664
19. Vatassery G.T., Smith W.E., and Quach H.T. Ascorbic acid, glutathione and synthetic antioxidants prevent the oxidation of vitamin E in platelets. Lipids 245 (1989) 1043-1047
20. Yan X., Zou J., and Xie G. Traditional Chinese Medicines: Molecular Structures, Natural Sources, and Applications (1999), Ashgate Publishing Company, USA pp. 722-730
21. Zhishen J., Mengcheng T., and Jianming W. The determination of flavonoid contents in mulberry and their scavenging effects on superoxide radicals. Food Chem. 64 (1999) 555-559
22. Zou Y., Lu Y., and Wei D. Antioxidant activity of a flavonoid-rich extract of Hypericum perforatum L. in vitro. J. Agric. Food Chem. 52 (2004) 5032-5039